Clinical trials: Spinal Nerve Root Disorder Nos
Cervical Radiculopathy
Manual Cervical Traction and Natural Apophyseal Glides for Cervical Radiculopathy Patients
Cervical Radiculopathy is a clinical disorder of nerve root, and often is due to compressive or inflammatory pathology. There are number of different procedures which have been suggested for decreasing pain and disability in…
- Trial name
- NCT04915222
- Testing
- Natural apophyseal glides, Cervical manual traction
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Lumbosacral Radicular Pain, Sciatic Radiculopathy
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to sterile saline
- Conditions
- Lumbosacral Radicular Pain, Sciatic Radiculopathy, Sciatic Leg Pain, Sciatica
- Trial name
- NCT07264270
- Testing
- C-1101
- Where
- 6 sites in United States, Australia
- Volunteers
- 24 people
- Sponsor
- Consano Bio
Cervical Pain
Ultrasound-guided Versus Combined Ultrasound and Fluoroscopy-guided Cervical Selective Nerve Root Block for Lower Cervical Radiculopathy: Non-inferiority Randomized Controlled Study
Cervical radiculopathy is a pain and/or sensorimotor deficit syndrome that is defined as being caused by compression of a cervical nerve root .The compression can occur as a result of disc herniation, spondylosis, instability…
- Trial name
- NCT05521373
- Testing
- ultrasound cervical selective nerve root block, ultrasound and fluoroscopy-guided cervical selective nerve root block
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cervical Disc Herniation, Intervertebral Disc Displacement
Gelified Radiopaque Ethanol (Absolute Gel) in Cervical Disc Herniation: an Observational Study in Routine Clinical Practice (GENESIS)
GENESIS is a single-centre, observational, non-interventional, no-profit, investigator-initiated study conducted at Ospedale di Vimercate, ASST Brianza (Italy).
- Conditions
- Cervical Disc Herniation, Intervertebral Disc Displacement, Neck Pain, Chronic Pain
- Trial name
- GENESIS (NCT07832929)
- Testing
- Absolute Gel (radiopaque gelified ethanol)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aurel Mengri
Cervical Radiculopathy
To Investigate the Effect of Modified Cawthorne-cooksey Exercises on Cervical Proprioception and Functional Outcomes in Patients With Cervical Radiculopathy. Fifty Four Patients With Cervical Radiculopathy From Both Sexes Will be Selected Randomly and Allocated Into Two Equal Groups.
To investigate the effect of cawthorne-cooksey exercises on cervical proprioception and functional outcomes in patients with cervical radiculopathy
- Trial name
- Cawthorne (NCT07323992)
- Testing
- Cawthorne-Cooksey exercises, Therapeutic Ultrasound
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- German International University
Cervical Radiculopathy
Effects of Laser Guided Cervical Proprioceptive Exercises in Patients With Cervical Radiculopathy
Cervical radiculopathy is a peripheral nervous system condition characterized by pathology of the cervical nerve root. Laser guided proprioceptive exercises shows positive impact in improving Joint sense error.
- Trial name
- NCT06397196
- Testing
- Laser guided proprioceptive exercises, Routine Physical therapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Lumbar Radiculopathy
Low Level LASER Therapy With and Without Proprioceptive Stimulation Among Discogenic Lumbar Radiculopathy Patients
The aim of this study is to evaluate the effects of low level laser therapy with and without proprioceptive stimulation on somatosensation, pain and gait parameters in patients with discogenic lumbar radiculopathy.
- Trial name
- NCT05953727
- Testing
- Low level laser therapy with proprioceptive stimulation, Low level laser therapy without proprioceptive stimulation
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Cervical Disc Herniation, Pain, Neuropathic
Effect of the Cervical Interlaminar Epidural Steroid Injection on Quality of Life, Pain and Disability
To evaluate the effect of cervical interlaminar epidural steroid injections on the neuropathic pain, quality of life and disability patients with cervical radiculopathy.
- Trial name
- NCT04235478
- Testing
- Combination Product: triamcinolone and saline
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Marmara University
Neuropathic Pain, Nociceptive Pain
PET/MRI in the Diagnosis of Chronic Pain
Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain.
- Conditions
- Neuropathic Pain, Nociceptive Pain, Mixed Pain (Nociceptive and Neuropathic), Spinal Pain
- Trial name
- NCT03556137
- Testing
- [18F]FTC-146
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lumbar Disc Disease
Intra-operatory Neurophysiological Monitoring Changes as a Predictive Clinical Outcome Measure in Lumbar Radiculopathy.
The purpose of this study is to determine the relation among: (1) changes in voltage and amplitude of trans-operatory records obtained through the use of Intra-operative Neurophysiological Monitoring (IONM), and (2) clinical…
- Trial name
- NCT02185508
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- American British Cowdray Medical Center
Cervical Radiculopathy
Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach
Do cervical epidural steroid injections done by transforaminal catheter targeted approach improve pain and function in patients with cervical radicular pain?
- Trial name
- NCT03382821
- Testing
- Transforaminal ESI with dexamethasone, Transforaminal catheter-targeted ESI with triamcinolone, Dexamethasone Sodium Phosphate 10 MG/ML
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Utah
Cervical Spondylosis, Cervical Spondylotic Myelopathy
Pregabalin and Radicular Pain Study (PARPS)
This study is designed to investigate the effectiveness of pregabalin (Lyrica) on nerve pain caused by degenerative neck problems. Pregabalin is a new drug registered for use in nerve pain worldwide
- Conditions
- Cervical Spondylosis, Cervical Spondylotic Myelopathy, Cervical Spondylotic Radiculopathy
- Trial name
- PARPS (NCT01061697)
- Testing
- Pregabalin
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Lumbar Degenerative Disc Disease
TRIUMPH Lumbar Artificial Disc IDE: A Pilot Study
The purpose of this investigation is to evaluate the safety and effectiveness of the TRIUMPH® Lumbar Artificial Disc for the treatment of patients who are suffering from Degenerative Disc Disease (DDD) at one level from L1 to S1.
- Trial name
- NCT01198470
- Testing
- TRIUMPH® Lumbar Artificial Disc
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Globus Medical Inc
Lumbosacral Radiculopathy, McKenzie Derangement Syndrome
Effect of Combined Lumbar Traction and Repetitive Back Extension Exercise on H-reflex in Lumbosacral Radiculopathy
The aim of the study is to investigate the effect of performing combined lumbar traction and repeated back extension exercise (McKenzie) on soleus H-reflex, pain, and disability in patients with lumbosacral radiculopathy.
- Trial name
- NCT06216288
- Testing
- Repeated back extension exercise (McKenzie), Mechanical traction
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Spinal Stenosis
Acupuncture for Lumbar Spinal Stenosis
Acupuncture is widely used to manage chronic low back pain. Mounting evidence suggests the beneficial effects of acupuncture for mitigating chronic low back pain with acceptable minor adverse events.
- Trial name
- NCT01987622
- Testing
- Acupuncture, Usual care
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Lumbar Radiculopathy
Comparative Effects Of High Intensity Spinal Decompression Exercises And Eldoa In Patients Of Lumbar Radiculopathy
To compare the effects of high intensity spinal decompression exercises and Eldoa on pain, ROM and Disability in patients of lumbar radiculopathy.
- Trial name
- NCT06087107
- Testing
- High Intensity Spinal Decompression Exercises, Eldoa
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation
STA363 in the Treatment of Lumbar Disc Herniation
The goal of this clinical trial is to establish safety and tolerability of STA363 injected into a herniated intervertebral disc in patients with sciatica due to disc herniation. The main questions the trial aims to answer are: 1.
- Trial name
- NCT06022263
- Testing
- Lactic Acid
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Stayble Therapeutics
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Lumbar Radiculopathy
Effect of Routine Physical Therapy With and Without Core Stability Exercises in Patients With Lumbar Radiculopathy
The goal of this Randomized controlled trial was to examine the effect of routine physical therapy with and without core stability exercises in patients with lumbar radiculopathy.
- Trial name
- NCT05741138
- Testing
- Core strengthening, Conventional treatment
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Sehat Medical Complex