Clinical trials: Spondylitis
Arthritis, Spondylitis, Ankylosing
Natural History and Development of Spondyloarthritis
Background: Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal bone growth affecting the joints and spine.
- Trial name
- NCT01422694
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis
2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis
This was an observational, prospective primary data collection study. The duration of observation was 2 years after study enrolment date.
- Conditions
- Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis
- Trial name
- PROMPT (NCT05155098)
- Testing
- secukinumab
- Where
- 10 sites in Thailand
- Volunteers
- 127 people
- Sponsor
- Novartis Pharmaceuticals
Rheumatic Diseases, Lupus Erythematosus, Systemic
Pain Phenotyping of Rheumatic Diseases - An Observational Study
Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and change nerve signals in the brain.
- Conditions
- Rheumatic Diseases, Lupus Erythematosus, Systemic, Lupus Vasculitis, Central Nervous System, Arthritis
- Trial name
- NCT07829497
- Testing
- Bedside quantitative sensory testing
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Ankylosing Spondylitis
Nurse-Led Exercise Program for Older Adults With Ankylosing Spondylitis
This study evaluated whether a nurse-led tailored exercise program improves spinal mobility, functional ability, pain, and health literacy in adults aged 60 years or older with ankylosing spondylitis.
- Trial name
- NCT07891507
- Testing
- Nurse-Led Tailored Exercise Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Cervical Spondylitis
Reciprocal Inhibition vs PNF for Cervical Spondylitis
Cervical spondylitis is a common cause of chronic neck pain and limited function. Physiotherapists often use two manual techniques: Reciprocal Inhibition (RI) and Passive Proprioceptive Neuromuscular Facilitation (PNF)…
- Trial name
- RI-PNF-CS (NCT07637812)
- Testing
- Reciprocal Inhibition Technique, Passive PNF Stretching
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Faisalabad
Ankylosing Spondylitis
A Phase III Study to Evaluate the Efficacy and Safety of AK111 in Subjects With Active Ankylosing Spondylitis
This is a randomized, double-blind, placebo-controlled, multi-center phase III clinical study to evaluate the efficacy and safety of AK111 in the treatment of subjects with active ankylosing spondylitis.
- Trial name
- NCT06378697
- Testing
- AK111
- Where
- 60 sites in China
- Volunteers
- 510 people
- Sponsor
- Akeso
Ankylosing Spondylitis (AS)
Posture Exercises in Ankylosing Spondylitis
This study will evaluate the effects of posture-focused exercises on spinal alignment in patients with ankylosing spondylitis. Participants will be randomly assigned to one of two groups.
- Trial name
- AS-POSTURE (NCT07879157)
- Testing
- Standard Breathing Exercise Program, Posture-Focused Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Mustafa Akça
Ankylosing Spondylitis
A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis
This study employs a randomized controlled trial methodology to systematically evaluate the efficacy and safety of a modified acupotomy technique in the treatment of ankylosing spondylitis.
- Trial name
- UGA-AS RCT (NCT07578220)
- Testing
- Ultrasound-guided acupotomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
Frequency and Complications of Major Orthopedic Procedures in Medicare Beneficiaries
Background: Orthopedic procedures are common in the United States. These include joint replacement and spine surgeries. Researchers want to study data about these procedures over time.
- Trial name
- NCT02281747
- Where
- United States
- Volunteers
- 521,292 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Axial Spondyloarthritis, Ankylosing Spondylitis
Surface Topography and Radiographic Spinal Damage in Radiographic Axial Spondyloarthritis
Radiographic axial spondyloarthritis (r-axSpA) causes progressive structural damage of the spine, conventionally quantified on lateral cervical and lumbar radiographs using the modified Stoke Ankylosing Spondylitis Spine Score…
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Spondylarthritis
- Trial name
- NCT07855393
- Testing
- DIERS Formetric 4D surface topography
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Ankara Etlik City Hospital
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Axial Spondyloarthritis, Ankylosing Spondylitis (AS)
Effects of Pulmonary Rehabilitation Exercises in Patients With Axial Spondyloarthritis
This prospective, randomized, single-blind controlled study evaluates the effects of pulmonary rehabilitation exercises in patients with axial spondyloarthritis. Participants were randomized into two groups.
- Trial name
- NCT07847879
- Testing
- Pulmonary Rehabilitation Program, Conventional Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Ankylosing Spondylitis
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis
The purpose of the study is to demonstrate the efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared to placebo in the treatment of subjects with active ankylosing spondylitis (AS).
- Trial name
- BE MOBILE 2 (NCT03928743)
- Testing
- Bimekizumab
- Where
- 83 sites in United States, Belgium and 12 more
- Volunteers
- 332 people
- Sponsor
- UCB Biopharma SRL
Ankylosing Spondylitis
Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS)
The purpose of this study is to determine if Jaktinib is safe and effective in participants with active ankylosing spondylitis.
- Trial name
- NCT05861128
- Testing
- Jaktinib
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Ankylosing Spondylitis
Efficacy and Safety Study of Jaktinib in Subjects With Active Ankylosing Spondylitis(AS)
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, efficacy and safety study of Jaktinib in subjects with active Ankylosing Spondylitis(AS).
- Trial name
- NCT05861102
- Testing
- Jaktinib
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Axial Spondyloarthritis and Ankylosing Spondylitis
Effects of Land- and Water-Based Exercise in Axial Spondyloarthritis
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by pain, morning stiffness, restricted spinal mobility, and systemic manifestations.
- Trial name
- NCT07833033
- Testing
- Land-Based Combined Exercise Program, Aquatic Combined Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Ankylosing Spondylitis
Lacticaseibacillus Rhamnosus GG Supplementation in Active Ankylosing Spondylitis
The goal of this clinical trial was to learn whether Lacticaseibacillus rhamnosus GG supplementation improves disease activity, physical function, and inflammatory markers in adults with active ankylosing spondylitis.
- Trial name
- NCT07834788
- Testing
- Lacticaseibacillus rhamnosus GG
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Acibadem University
Ankylosing Spondylitis
Wet Cupping Therapy in Ankylosing Spondylitis
This study evaluates the efficacy of wet cupping therapy in patients with ankylosing spondylitis.Wet cupping therapy will be applied to half of the patients plus routine pharmaceutical treatment while the other half will receive…
- Trial name
- NCT05792358
- Testing
- wet cupping therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Ankylosing Spondylitis, Axial Spondyloarthritis
Taekwondo for Axial Spondyloarthritis
The goal of this clinical trial is to learn if Taekwondo training works to help adults with ankylosing spondylitis and axial spondyloarthritis. It will also learn about the safety of Taekwondo training for these adults.
- Trial name
- NCT06823726
- Testing
- 12-week Taekwondo training
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Wonju Severance Christian Hospital
Osteo Arthritis Shoulders, Osteonecrosis
Exactech Shoulder Post Market Clinical Follow-up Study
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time.
- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
- Trial name
- NCT05603728
- Where
- 40 sites in United States, Canada and 4 more
- Volunteers
- 20,000 people
- Sponsor
- Exactech