Clinical trials: Spondylolysis
Pneumothorax, Intestinal Obstruction
The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance
This study tests whether an artificial intelligence (AI) tool helps radiologists read X-rays more accurately. Radiologists read X-rays to find diseases such as pneumonia, bone fractures, and abdominal problems.
- Conditions
- Pneumothorax, Intestinal Obstruction, Spondylolysis, Renal Calculus
- Trial name
- NCT07870928
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Spondylolysis Lumbar
A Pilot Study on the Safety of Active Conservative Management of Low Grade Lumbar Stress Reactions in Adolescent Soccer Players
Introduction: The Background Prevalence: Low back pain (LBP) is very common in young athletes, and lumbar spondylolysis (an overuse injury of bones in the low back) is the leading cause.
- Trial name
- ActiveBack (NCT07430072)
- Testing
- Active rehabilitation protocol
- Where
- 3 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Western Norway University of Applied Sciences
Spondylolysis, Symptomatic Spondylolysis
Bone Stimulator for Spondylolysis
This prospective study aims to investigate the effectiveness of bone stimulator therapy as adjunct treatment of spondylolysis in athletic populations.
- Conditions
- Spondylolysis, Symptomatic Spondylolysis, Athletes
- Trial name
- NCT06666608
- Testing
- Bone Stimulator, Standard of Care Spondylolysis Treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The Methodist Hospital Research Institute
Chronic Low-back Pain, Degenerative Disc Disease
Postmarket Clinical Follow-Up Study on Arcadius XP L® Interbody Fusion Device
The purpose of this study is to collect clinical and radiological mid-term (min. 1 year) data on the ArcadiusXP L® lumbar stand-alone cage in a post-market clinical follow-up study (PMCF) limited to 60 patients.
- Conditions
- Chronic Low-back Pain, Degenerative Disc Disease, Spondylolysis Lumbar, Postdiscectomy Syndrome
- Trial name
- ARREST (NCT05944081)
- Testing
- ArcadiusXP L® Interbody Fusion System
- Where
- 3 sites in Germany
- Sponsor
- Aesculap AG
Spondylolysis
Association Of Serum Vitamin D Level With Isthmic Spondylolysis
The aim of this study is to compare vitamin D level between young adults with isthmic spondylolysis and a matched healthy control group.
- Trial name
- NCT06284967
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Assiut University
Low Back Pain, Stress Fracture
Treatment of Spondylolysisin Pediatric Patients.
A clinical trial comparing healing of unilateral or bilateral spondylolysis in children treated with a Boston thoracolumbar orthosis (brace) or with a soft spinal brace (Porostrap lumbar support) for four months.
- Trial name
- NCT03675152
- Testing
- Soft spinal brace, thoracolumbar orthosis, Excersice restriction
- Where
- 2 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Degenerative Disc Disease, Osteochondrosis
MySpine MC Versus MySpine Standard
This research project compares the clinical performance of the cortical bone trajectory CBT insertion technique with the current clinical Gold standard, the Pedicle screw insertion technique.
- Conditions
- Degenerative Disc Disease, Osteochondrosis, Spondylolysis Lumbar
- Trial name
- MC vs STD (NCT05846477)
- Testing
- MySpine
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Medacta International SA
Spondylolysis, Spondylolisthesis
Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis
This is a retrospective chart review with a short follow-up phone questionnaire for our patients who have been treated by Nationwide Children's Hospital physical therapy and sports medicine for a spondylolysis or…
- Conditions
- Spondylolysis, Spondylolisthesis, Low Back Pain
- Trial name
- NCT02332200
- Testing
- Physical Therapy
- Where
- 4 sites in United States
- Volunteers
- 196 people
- Sponsor
- Nationwide Children's Hospital
Spondylolysis
Effects of Low-intensity Pulsed Ultrasound on Pain and Functional Disability in Patients With Lumbar Spondylolysis
Low-intensity pulsed ultrasound (LIPUS) is effective in accelerating the healing of fractures, reduction in costs to the state, reduction in the numbers of those patients who progress from out-patient care to long term care who…
- Trial name
- NCT04814979
- Testing
- Low-intensity pulsed ultrasound (LIPUS), Routine physical therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Lahore
Low Back Pain, Lumbosacral Radiculopathy
A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief
The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of…
- Conditions
- Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation
- Trial name
- NCT03514277
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Low Back Pain, Spondylolysis
Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain
The goal of the proposed research is to test the feasibility of a functional progression program to reduce cost and possible radiation exposure for adolescent athletes with low back pain.
- Conditions
- Low Back Pain, Spondylolysis, Spondylolisthesis
- Trial name
- NCT02861456
- Testing
- Standard Model of Care, Alternative Model of Care
- Where
- 4 sites in United States
- Volunteers
- 16 people
- Sponsor
- Nationwide Children's Hospital
Lumbar Degenerative Disc Disease, Spinal Stenosis
Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease
The purpose of this study is to compare the effect and safety of NuCel to DBX on patients undergoing posteriolateral lumbar spinal fusions for degenerative disc disease.
- Conditions
- Lumbar Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Spondylosis
- Trial name
- NCT02070484
- Testing
- NuCel, Demineralized Bone Matrix
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- OhioHealth
Spine; Arthrosis, Spondylolysis
Immune Effect of Dexmedetomidine in Patients Undergoing to Spinal Fusion
Alpha-agonist in anesthesia display immunomodulatory effect in addition to antiadrenergic control. This effect of the immune system can be a key to a better perioperative safety and quality.
- Conditions
- Spine; Arthrosis, Spondylolysis, Spondylolysis, Multiple Sites in Spine, Spondylolisthesis
- Trial name
- eMUNODEX (NCT02854904)
- Testing
- Dexmedetomidine intervention
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Sarah Network of Rehabilitation Hospitals
Spondylolisthesis, Spondylolysis
The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or Spondylolisthesis
Purpose: To determine the effectiveness of an augmented Pilates program, when combined to a multimodal strengthening program, for patients under the age of 21, who have spondylolysis and/or spondylolisthesis.
- Conditions
- Spondylolisthesis, Spondylolysis, Children
- Trial name
- NCT01711203
- Testing
- Motor Control, General Strengthening
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Megan Donaldson PT, PhD, FAAOMPT
Spondylolysis
Direct Repair Surgery for Spondylolysis of Lumbar in Young Population
Lumbar spondylolysis is a relatively common condition that causes severe and perennial back pain in young populations. Conservative treatment of this condition may be futile, and may eventually require surgical treatment such as…
- Trial name
- NCT02129374
- Testing
- Direct repair of pars defect
- Where
- South Korea
- Volunteers
- 163 people
- Sponsor
- Seoul National University Hospital