Clinical trials: Spondylosis
Low Back Pain, Spondylolisthesis
Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain
this study aims to evaluate balance using the biodex balance system among patients with spondylosis, spondylolisthesis, and lumber disc prolapse.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis Lumbar, Balance Assessment
- Trial name
- Biodex (NCT07242976)
- Testing
- Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spondylosis Lumbar
Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine Osteoarthritis
Chronic low back pain due to lumbar spine osteoarthritis is a common and disabling condition. Many patients do not get enough relief from standard treatments.
- Trial name
- NCT06874959
- Testing
- Battlefield Acupuncture (BFA), Electroacupuncture, Paracetamol 500 mg (as-needed)
- Where
- 2 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- Bui Pham Minh Man
Cervical Stenosis, Myelopathy
Assessing Microbiome in Primary Anterior Cervical Fusion Patients
Patients who are about to undergo cervical fusion surgery at Hospital for Special Surgery (HSS) are being asked to take part in this research study.
- Conditions
- Cervical Stenosis, Myelopathy, Cervical Spondylosis With Myelopathy, Degenerative Disc Disease
- Trial name
- NCT07877766
- Testing
- Primary Anterior Cervical Discectomy Procedures
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Lumbar Spondylosis, Fusion of Spine
To Brace or Not to Brace for Single Level Lumbar Fusion Pilot
The use of a lumbar brace following single-level lumbar fusion for degenerative spondylosis (non-traumatic) is variable between surgeons. Some surgeons prefer to prescribe a brace and others do not.
- Trial name
- BRACE Pilot (NCT03439228)
- Testing
- Lumbar brace
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Hamilton Health Sciences Corporation
Spinal Stenosis Cervical, Radiculopathy, Cervical Region
Hard Cervical Collar Use Following Posterior Cervical Fusion
Postoperative immobilization with a hard cervical collar following posterior cervical fusion remains common practice despite limited evidence demonstrating improved clinical outcomes.
- Conditions
- Spinal Stenosis Cervical, Radiculopathy, Cervical Region, Posterior Cervical Fusion, Spondylosis, Cervical
- Trial name
- NCT07789288
- Testing
- Hard Cervical Collar
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Georgetown University
Cervical Spondylosis
Effectiveness of Pressure Biofeedback-Assisted Deep Cervical Flexor Training With and Without Scapular Stabilization Exercises on Pain, Range of Motion and Neck Disability in Cervical Spondylosis
This randomized controlled trial will evaluate the effectiveness of pressure biofeedback-assisted deep cervical flexor training with and without scapular stabilization exercises in patients with cervical spondylosis.
- Trial name
- NCT07814833
- Testing
- Pressure Biofeedback-Assisted Deep Cervical Flexor Training, Scapular Stabilization Exercises, Standard Physiotherapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Cervical Radicular Pain, Spondylosis, Cervical
Patient Reported Recovery of Muscle Strength After Surgery for Cervical Radiculopathy, Impact of Duration and Severity on Recovery.
DCR surgery is generally recommended for patients with severe or progressive limb paresis. The incidence of motor weakness reported to be up to 70%, with a varying recovery rate up to 90%, and the prospects of recovery is most…
- Conditions
- Cervical Radicular Pain, Spondylosis, Cervical, Cervical Disc Herniation, Cervical Spine Disc Disease
- Trial name
- NCT07825545
- Testing
- Anterior cervical discetomi and fusion/posterior decompression
- Where
- Norway
- Volunteers
- 2,000 people
- Sponsor
- University Hospital of North Norway
Lumbar Spondylosis
RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar Spondylosis
Spondylosis is an anatomical defect of the small facet joints between the spinal vertebrae often due to load bearing and mechanical wear. It is a major contributor to lower back pain.
- Trial name
- NCT06477094
- Testing
- Stratus Nimbus Electrosurgical RF Multi-Tined Expandable Electrode, Stryker Venom Radiofrequency Cannula
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Arkansas
Cervical Spondylosis, Neck Pain
Comparative Effects of Gong's Mobilization and Maitland Mobilization in Patients With Cervical Spondylosis
Cervical spondylosis is a degenerative condition of the cervical spine that may cause neck pain, reduced cervical range of motion, muscle weakness, and functional disability.
- Conditions
- Cervical Spondylosis, Neck Pain, Manipulation
- Trial name
- GONG-MAIT (NCT07808372)
- Testing
- Gong's Mobilization, Maitland Cervical Mobilization
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Faisalabad
Spondylosis, Spondylolisthesis
Comparison of Radiographic Fusion Rate and Clinical Outcome of ALIF and XLIF Performed With Either Recombinant Human Bone Morphogenetic Protein-2 or ViviGen®
The aim of this study is to prospectively investigate the potential for bony fusion of ViviGen® bone graft substitute in comparison to rhBMP-2 in monosegmental ALIF procedure L5/S1 and in monosegmental XLIF procedure L4/5
- Conditions
- Spondylosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- NCT05238740
- Testing
- ViviGen®, rhBMP-2
- Where
- Switzerland
- Volunteers
- 168 people
- Sponsor
- Lindenhofgruppe AG
Chronic Pain, PERIPHERAL NEUROPATHY
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
- Conditions
- Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain
- Trial name
- NCT07639060
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Pain, Back, Spinal Stenosis
PREventing Pain After Surgery
The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis
- Trial name
- PREPS (NCT05306665)
- Testing
- ACT intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Brigham and Women's Hospital
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Chronic Low Back Pain (CLBP), Lumbar Spondylosis
Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain.
Chronic low back pain (CLBP) due to lumbar spondylosis is a leading cause of disability, significantly impacting the quality of life in middle-aged and elderly populations.
- Trial name
- NCT07530042
- Testing
- Electroacupuncture, Auricular Acupressure
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Cervical Spondylosis, Neck Pain
High-Frequency Electroacupuncture at Cervical Huatuo Jiaji Points Combined With Electromagnetic Field Therapy for Cervical Spondylotic Radiculopathy
Cervical spondylotic radiculopathy (CSR) is one of the most common manifestations of cervical spondylosis and is characterized by neck pain radiating to the upper extremities, sensory disturbances, restricted cervical range of…
- Conditions
- Cervical Spondylosis, Neck Pain, Cervical Spondylotic Radiculopathy
- Trial name
- NCT07712354
- Testing
- High-Frequency Electroacupuncture at Cervical Huatuo Jiaji (EX-B2), Pulsed Electromagnetic Field Therapy, Conventional High-Frequency Electroacupuncture
- Where
- Vietnam
- Volunteers
- 104 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Lumbar Spondylosis
Comparative Effectiveness of Two Different Approaches to Radiofrequency Ablation of Lumbar Medial Branch Nerves
The purpose of this voluntary research study is to determine whether the parasagittal approach to lumbar medial branch (LMB) nerve radio frequency ablation (RFA) will have greater efficacy than the traditional approach to lumbar…
- Trial name
- LMB-RFA (NCT06283628)
- Testing
- Radiofrequency ablation of lumbar medial branch nerves.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Milton S. Hershey Medical Center
Cervical Spondylosis, Wind-Cold Syndrome
Efficacy of Three-Needle Dazhui and Electroacupuncture for Cervical Spondylosis With Wind-Cold Syndrome
Cervical spondylosis is a prevalent health issue that significantly impacts quality of life, with Cervical Spondylotic Radiculopathy (CSR) accounting for 60-70% of cases While modern medicine offers various treatments, the…
- Conditions
- Cervical Spondylosis, Wind-Cold Syndrome, Neck Pain, Cervical Spondylotic Radiculopathy
- Trial name
- NCT07640126
- Testing
- Standard Electroacupuncture, Three-Needle Dazhui Technique & Electroacupuncture, Standard Care Drugs
- Where
- Vietnam
- Volunteers
- 74 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Spinal Cord Injuries, Neuropathic Pain
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due to traumatic or non-traumatic (degenerative) spinal cord injury.
- Conditions
- Spinal Cord Injuries, Neuropathic Pain, Degenerative Disc Disease, Spinal Stenosis
- Trial name
- NCT06438471
- Testing
- EC5026 oral tablet
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- EicOsis Human Health Inc.
Grade-II Cervical Spondylosis
Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical…
- Trial name
- NCT07679373
- Testing
- Group A: Clinical Based Rehabilitation, Group B: Synchronized Telerehabilitation
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences