Clinical trials: Spontaneous Intracerebral Hemorrhage
Intracerebral Hemorrhage
Efficacy and Safety of Factor VIIa on Rebleeding After Surgery for Spontaneous Intracerebral Hemorrhage (ICH)
Although the role of surgical treatment is still controversial, surgical evacuation of intracerebral hematoma is a frequent practice. Rebleeding is a frequent complication in patients submitted to hematoma evacuation.
- Trial name
- PRE-SICH (NCT00128050)
- Testing
- rFactor VIIa (Eptacog alfa, NovoNordisk), rFVIIa, Sodiun chloride 0.9%
- Where
- 3 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Spontaneous Intracranial Hemorrhage, Spontaneous Intraparenchymal Cerebral Hemorrhage
The Influencing Factors and Prediction Model of Poor Prognosis of Spontaneous Intraparenchymal Hemorrhage
This study was designed to explore the influencing factors of spontaneous intraparenchymal hemorrhage's prognosis and develop predictive models for poor prognosis by establishing a cohort of spontaneous intraparenchymal…
- Conditions
- Spontaneous Intracranial Hemorrhage, Spontaneous Intraparenchymal Cerebral Hemorrhage, Spontaneous Cerebellar Haemorrhage
- Trial name
- NCT03899350
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tang-Du Hospital
Cerebral Hemorrhage
Multimodal Monitoring in Patients With Spontaneous Intracerebral Hemorrhage
Spontaneous intracerebral bleeding also known as spontaneous intracerebral hemorrhage (sICH) constitute 10-15 % of all apoplexies.
- Trial name
- NCT02326571
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Christian Kærsmose Friberg
Intracerebral Hemorrhage
Statins in Patients With Spontaneous Intracerebral Hemorrhage
The relation between improvement in results of treating spontaneous intracerebral hemorrhage (SICH) and the application of statins has been subject to numerous analyses, and yet still remains debatable.
- Trial name
- NCT06094244
- Testing
- Atorvastatin, Rosuvastatin, No drugs
- Where
- Poland
- Volunteers
- 153 people
- Sponsor
- Pomeranian Medical University Szczecin
Intracerebral Hemorrhage, Critically Ill
Early Multimodal Neuromonitoring For Spontaneous Intracerebral Hemorrhage (ICH)
The investigators intend to assess the predictive value of early (first 48 hours) multimodal neuromonitoring parameters concerning late survival in critically ill intracerebral hemorrhage (ICH) patients.
- Conditions
- Intracerebral Hemorrhage, Critically Ill, Intracranial Pressure, Cerebral Perfusion Pressure
- Trial name
- NCT05501613
- Testing
- Multimodal Neuromonitoring
- Where
- Portugal
- Volunteers
- 65 people
- Sponsor
- Universidade do Porto
Intracerebral Hemorrhage Lobar
Neuronavigation-assisted Stereotactic Minimally Invasive Puncture With Tenecteplase for Acute Lobar Intracerebral Hemorrhage
Introduction: Minimally invasive puncture surgery with thrombolysis is effective for hypertensive intracerebral hemorrhage, but its effect on neurological recovery remains uncertain.
- Trial name
- NALICE-TNK (NCT07471256)
- Testing
- Neuronavigation-assisted Stereotactic Minimally Invasive Puncture Combined with Tenecteplase, Standard medical treatment
- Where
- China
- Volunteers
- 636 people
- Sponsor
- Beijing Tiantan Hospital
Spontaneous Intracerebral Hemorrhage
Risk Stratification and Minimally Invasive Surgery in Acute ICH Patients
The study consists of 2 parts: the first part is to conduct a multicenter retrospective analysis of more than 1000 acute ICH patients treated by conservative observation from 33 centers in China to create a predictive model of…
- Trial name
- Risa-MIS-ICH (NCT03862729)
- Testing
- Minimally invasive surgery, conventional treatment
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Intra Cerebral Hemorrhage, Hypertension
Proper Timing of Control of Hypertension and Outcome in Acute Spontaneous Intracerebral Hemorrhage.
The ideal management of blood pressure in BP after acute intracerebral haemorrhage is still debated and whether a higher intensive reduction of blood pressure after acute intracerebral haemorrhage may be better or not is still…
- Trial name
- NCT04167644
- Testing
- Modified Rankin Scale (mRS)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University Hospital
Hypertensive Intracerebral Hemorrhage
Modified Stereotactic Aspiration and Thrombolysis of Intracerebral Hemorrhage:a Multi-center Controlled Study
The purpose of this study is to evaluate the superiority of effect of the modified micro-invasive aspiration and drainage and conservative medical therapy in the treatment of ICH spontaneously hypertensive scientifically.
- Trial name
- MSATIH (NCT00940745)
- Testing
- Stereotactic Aspiration and Thrombolysis, conservative treatment
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Intracerebral Hemorrhage
A Study to Evaluate the Safety, Tolerability and the Effects of Ixodes Ricinus-Contact Phase Inhibitor (Ir-CPI) in Adult Patients With Spontaneous Intracerebral Haemorrhage
The purpose of the study is to provide a first assessment of safety, tolerability and efficacy of Ir-CPI, administered on top of standard-of-care, on secondary brain injury in patients with spontaneous intracerebral haemorrhage.
- Trial name
- BIRCH (NCT05970224)
- Testing
- Ir-CPI
- Where
- 8 sites in Belgium
- Volunteers
- 23 people
- Sponsor
- Bioxodes S.A.
Cerebral Hemorrhage
REstart or STop Antithrombotic Randomised Trial in France
RESTART- fr is a randomised controlled trial for adults surviving spontaneous intracerebral haemorrhage who had taken an antithrombotic drug (i.e.
- Trial name
- RESTART-Fr (NCT02966119)
- Testing
- Clopidogrel or Aspirin and/or Dypyridamole
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Lille
Intracerebral Hemorrhage
REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.
Intracerebral hemorrhage (ICH) remains the most devastating subtype of stroke, with a case fatality rate of approximately 40% at one months post-onset, imposing a particularly heavy medical and economic burden on low- and…
- Trial name
- READY-ICH (NCT07695220)
- Testing
- Remifentanil and Dexmedetomidine, Guideline standard care
- Volunteers
- 1,116 people
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Intracerebral Hemorrhagic Stroke
Indian Trial of Tranexamic Acid in Spontaneous Intracerebral Haemorrhage
This multicenter, pragmatic randomized, open-label clinical trial aims to assess whether Tranexamic Acid improves outcomes in adult patients with spontaneous intracerebral haemorrhage.
- Trial name
- NCT05836831
- Testing
- Tranexamic acid injection
- Where
- 48 sites in India
- Volunteers
- 3,400 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Early Systolic Blood Pressure Control Rate, Hematoma Growth
Analgesia-first Minimal Sedation for Spontaneous Intracerebral Hemorrhage Early Antihypertensive Treatment
This study evaluates safety and efficacy of analgesia-first minimal sedation as an early antihypertensive treatment for spontaneous intracerebral hemorrhage.
- Conditions
- Early Systolic Blood Pressure Control Rate, Hematoma Growth, Blood Pressure Variability, Healthcare Worker Satisfaction
- Trial name
- ASSICHH (NCT03207100)
- Testing
- Analgesia-first minimal sedation, Antihypertensive treatment
- Where
- 17 sites in China
- Volunteers
- 338 people
- Sponsor
- Hong Yang
Intracerebral Hemorrhage, Hemorrhagic Stroke
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
- Trial name
- CR-4-Health (NCT07882784)
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 300 people
- Sponsor
- University Medical Centre Maribor
Hemorrhage, Intracranial, Outcome Measure
Clinical Characteristics and Outcome of Patients With Hemorrhagic Stroke Admitted in Neurology Department in a Tertiary Hospital
The main aim of this study is to know about the clinical profile of patients who are diagnosed as hemorrhagic stroke as well as the factors that affect good and bad outcomes of those patients after 3 months.
- Trial name
- NCT06824311
- Where
- Nepal
- Volunteers
- 197 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Intracerebral Hemorrhage
Multicentre Registry of Patients With Spontaneous Acute Intracerebral Hemorrhage in Catalonia (HIC-CAT).
A population-based registry in Catalonia of patients with acute spontaneous Intracerebral Hemorrhage, to investigate whether type of center and time from onset to admission is associated with functional outcome and mortality.
- Trial name
- HIC-CAT (NCT03956485)
- Testing
- Type of center
- Where
- 26 sites in Spain
- Volunteers
- 2,500 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Intracerebral Hemorrhage, Cerebral Hemorrhage
MIECH: The Minimally Invasive Endoscopic Surgery With the Axonpen System for Spontaneous Intracerebral Hemorrhage
The primary objective of this trial is to provide preliminary safety data of minimally invasive endoscopic surgery using the Axonpen™ system for spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Intracerebral Hemorrhage, Cerebral Hemorrhage, Intracranial Hemorrhage, Basal Ganglia Hemorrhage
- Trial name
- NCT04839770
- Testing
- Axonpen system
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Clearmind Biomedical Inc.
Intracranial Hemorrhages
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Spontaneous Intracerebral Hemorrhage
The purpose of this study is to determine whether treatment with remote ischemic conditioning is of sufficient promise to improve outcome before conducting a larger clinical trial to examine its effectiveness as a treatment for…
- Trial name
- SERIC-sICH (NCT03484936)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 530 people
- Sponsor
- Yi Yang
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment
Background: Despite the capability of emergency surgery to reduce the mortality of severe spontaneous intracranial hemorrhage (SSICH) patients, the effect and safety of surgical treatment for severe spontaneous intracranial…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05766865
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital