Clinical trials: Stable Chronic Angina
Stable Angina, Coronary Artery Disease
CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
The "DATASET-PRECISE", a 3-arm parallel randomized study, aims to provide new insights in risk stratification of patients with suspected CAD in the Greek population.
- Conditions
- Stable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery Calcification
- Trial name
- DATASET (NCT04424121)
- Testing
- CCTA
- Where
- 3 sites in Greece
- Volunteers
- 900 people
- Sponsor
- Aristotle University Of Thessaloniki
Acute Myocardial Infarction, Percutaneous Coronary Intervention
Enhancing Cardiac Rehabilitation Through Behavioral Nudges
Adherence to cardiac rehabilitation is poor, and worse for minorities, women, and those with lower levels of education. Patients less likely to be referred to and complete cardiac rehab are at highest risk of adverse outcomes and…
- Conditions
- Acute Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Disease, Valvular Disease
- Trial name
- NCT03834155
- Testing
- Hospital-based CR + Movn Application, Choice of Hospital or home-based CR + Movn Application, Hospital-based CR + Movn Application + Nudge
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Denver Health and Hospital Authority
Chronic Stable Angina Pectoris
Acute Episodes in Chronic Stable Angina: Assessment of the Use of the Coronary Vasodilator Propatyl Nitrate.
This is an open, self-paired study of 200 patients with heart failure who have a diagnosis of chronic stable angina pectoris, who will be treated for 30 days with propatyl nitrate (10mg) .
- Trial name
- NCT02315976
- Testing
- Propatyl Nitrate
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
The purpose of the BRIDGE study is to learn whether supplementing traditional center-based cardiac rehabilitation (CBCR) with a mobile health technology intervention can help patients monitor their health, stay engaged in healthy…
- Conditions
- Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft Surgery (CABG), Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BRIDGE (NCT07741396)
- Testing
- CBCR, BRIDGE mHealth intervention
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Stable Angina, Unstable Angina
Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registry
A multi-center, prospective, consecutive enrolled, observational registry. The population being studied includes all patients undergoing treatment of "de novo" lesions in native coronary vessels, saphenous vein graft and/or…
- Conditions
- Stable Angina, Unstable Angina, ACS - Acute Coronary Syndrome, STEMI
- Trial name
- eCOBRA (NCT03103620)
- Testing
- COBRA PzF Coronary Stent System
- Where
- 18 sites in France
- Volunteers
- 1,027 people
- Sponsor
- CeloNova BioSciences, Inc.
Stable Angina, Coronary Artery Disease
Development and Validation of a Fast, Semi-Automated Hybrid Imaging Platform to Assess Coronary Atherosclerotic Plaque Morphology, Endothelial Shear Stress and Arterial Inflammation: A Proof of Principle Study (VALID-PET-CT)
Imaging the inside of coronary arteries (intravascular imaging) offers great insight into the assessment and treatment of coronary artery disease.
- Trial name
- VALID-PET-CT (NCT04205110)
- Testing
- PET-CT
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Barts & The London NHS Trust
Angina, Stable, Angina, Unstable
Atherosclerotic Lesion Proteomics by Harvesting Angioplasty Balloons (ALPHA).
The purpose of the study is to identify proteins, metabolites and signal pathways related directly to symptomatic atherosclerosis and to disease progression.
- Conditions
- Angina, Stable, Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), ST-segment Elevation Myocardial Infarction (STEMI)
- Trial name
- NCT05319366
- Where
- 2 sites in Denmark
- Volunteers
- 225 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Grey-zone Fractional Flow Reserve, Intermediate Coronary Lesions
A Trial in Stable Intermediate Coronary Lesions and Grey-zone FFR Values
In this randomised controlled trial of patients with stable angina and documented intermediate coronary disease with indeterminate or "grey-zone" Fractional Flow Reserve (FFR) we will randomise patients to either optimal medical…
- Conditions
- Grey-zone Fractional Flow Reserve, Intermediate Coronary Lesions, Stable Angina, Coronary Physiology
- Trial name
- GzFFR (NCT02425969)
- Testing
- PCI, Optimal Medical Therapy
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Golden Jubilee National Hospital
Stable Angina, Unstable Angina
Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions
This randomized trial will assess the efficacy of Drug Coated Balloon (DCB) compared to Bare Metal Stent (BMS) using Fractional Flow Reserve (FFR) guidance for de novo coronary artery lesions in patients unable to tolerate dual…
- Trial name
- NCT02456402
- Testing
- Drug Coated Balloon, Bare Metal Stent
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ulsan University Hospital
Stable Angina
Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation
Treatments for stable angina includes drug therapy such as calcium-channel blocker, beta blocker, and ACEI/ARB. To obtain good prognosis in patients with coronary artery disease,preventing or correcting the progression of…
- Trial name
- NCT01162902
- Testing
- Diltiazem treated group, Bisoprolol treated group, Candesartan treated group
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Chronic Stable Angina, PTCA
Myocardial Damage and Music Study
MYDA-MUSIC study is a randomized, double blind (operator and analyst) study performed in San Filippo Neri Hospital, Roma, Italy and in Di Venere Hospital, Bari, Italy. The planned study duration is 12 months.
- Trial name
- MYDA-MUSIC (NCT03507361)
- Testing
- HRV-BASED MUSIC
- Where
- Italy
- Volunteers
- 443 people
- Sponsor
- San Filippo Neri General Hospital
Myocardial Infarction, Acute Coronary Syndrome
HeartHome: A Nurse-Driven, Home-Based Cardiac Rehabilitation Program
The purpose of this implementation trial is to execute a nurse-led, home-based cardiac rehabilitation (HBCR) program, evaluate the program's impact on patient outcomes over 6 months; and compare outcomes of HeartHome (HH)…
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Trial name
- NCT04131816
- Testing
- HeartHome
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of North Carolina, Chapel Hill
Stable Angina Pectoris
Prevalence and Prognostic Value of Unrecognized Myocardial Injury in Stable Coronary Artery Disease (PUMI)
This study includes patients with stable coronary artery disease without previously known myocardial infarction, and investigates the prevalence of clinically unrecognized myocardial damage and its prognostic implication.
- Trial name
- PUMI (NCT01257282)
- Where
- 6 sites in Sweden
- Volunteers
- 275 people
- Sponsor
- Uppsala University
Adrenergic Beta-Antagonists, Stable Angina Pectoris
A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)
The present study aims to enhance the adherence of beta-blockers by Patient Support Tool through a smart phone application and a wristband, subsequently reduce the risk of angina attacks in patients with stable angina pectoris.
- Conditions
- Adrenergic Beta-Antagonists, Stable Angina Pectoris, Medication Adherence, Mobile Applications
- Trial name
- NCT03794713
- Testing
- Patient support tool
- Volunteers
- 432 people
- Sponsor
- Shenyang Northern Hospital
Angina Pectoris, Acute Myocardial Infarction
Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome
Previous trials have demonstrated that the use of physiological assessment of stenosis severity using fractional flow reserve (FFR) is superior to angiographic assessment in percutaneous coronary intervention (PCI) and improves…
- Trial name
- iFR Swedeheart (NCT02166736)
- Testing
- iFR, FFR
- Where
- 14 sites in Denmark, Iceland and 1 more
- Volunteers
- 2,037 people
- Sponsor
- Uppsala University
Stable Angina
Stable Angina Observational Registry
The purpose of this study is to describe the clinical profile and current status of the diagnosis and management of stable angina in India by non-interventional consulting physicians (CP) through a large multicenter observational…
- Trial name
- STAR (NCT01552109)
- Where
- India
- Volunteers
- 2,079 people
- Sponsor
- Medtronic Vascular
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
Stable Angina, Positive ETT
Diagnostic Value of HS-CRP in Stable Angina.
The aim of this study was to assess the amount of additive value of HS-CRP levels to a positive exercise tolerance test (ETT) in predicting coronary artery disease (CAD) using coronary angiography as the gold standard.
- Trial name
- NCT00719992
- Testing
- coronary angiography
- Where
- Iran
- Volunteers
- 97 people
- Sponsor
- Shiraz University of Medical Sciences