Clinical trials: Stage I Breast Cancer AJCC v7
Radiation Toxicity, Recurrent Breast Cancer
Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy
This phase II trial is studying how well alkaline water works in reducing skin toxicity in women with breast cancer undergoing radiation therapy.
- Conditions
- Radiation Toxicity, Recurrent Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01487954
- Testing
- alkaline water, distilled water, external beam radiation therapy (EBRT)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Obesity
Weight Loss Counseling for African American Women Who Are Breast Cancer Survivors
RATIONALE: A culturally sensitive weight loss program for obese African American breast cancer survivors may be more effective than a standard weight loss program in helping women lose weight.
- Conditions
- Breast Cancer, Obesity, Weight Changes
- Trial name
- NCT00872677
- Testing
- Diet, Spiritual counseling
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
De-escalation Therapy in Stage I ER-Positive Breast Cancer: A Non-Inferiority Trial
This study is a prospective, randomized, open-label, non-inferiority Phase III clinical trial, planning to enroll 2,934 patients, with a 1:1 allocation to either the conventional endocrine therapy group or the de-escalation…
- Trial name
- DESCENT (NCT07153757)
- Testing
- Endocrine Therapy of Physician's Choice
- Where
- China
- Volunteers
- 2,934 people
- Sponsor
- Fudan University
Breast Cancer
Clinical Trial of Trametes Versicolor in Women With Breast Cancer
RATIONALE: Coriolus versicolor mushroom extract may slow the growth of cancer cells and may be an effective treatment for breast cancer.
- Trial name
- NCT00680667
- Testing
- Coriolus versicolor extract
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Breast Cancer, Contralateral Breast Cancer
Magnetic Resonance Imaging in Women Recently Diagnosed With Unilateral Breast Cancer
RATIONALE: Diagnostic procedures such as magnetic resonance imaging (MRI) may improve the ability to detect cancer in the unaffected breast of women recently diagnosed with unilateral breast cancer.
- Trial name
- ACRIN-6667 (NCT00058058)
- Testing
- MRI
- Where
- 21 sites in United States, Canada and 1 more
- Volunteers
- 1,007 people
- Sponsor
- American College of Radiology Imaging Network
Breast Cancer
Octreotide, Tamoxifen, and Chemotherapy in Treating Women With Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more tumor cells.
- Trial name
- NCT00002967
- Testing
- cyclophosphamide, doxorubicin hydrochloride, octreotide pamoate
- Where
- 108 sites in United States, Canada
- Sponsor
- NSABP Foundation Inc
Chemotherapy-Related Nausea and/or Vomiting, Early Stage Breast Carcinoma
Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
This pilot study seeks to understand how changes in the bacteria composition (microbiome) of the gut may be associated with the occurrence of fatigue and chemotherapy-induced nausea (CIN) in women undergoing chemotherapy for…
- Conditions
- Chemotherapy-Related Nausea and/or Vomiting, Early Stage Breast Carcinoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT05417867
- Testing
- Biospecimen Collection, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
Breast Cancer
Partial Breast Radiation Therapy in Treating Women Undergoing Breast-Conserving Therapy for Early Stage Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Trial name
- NCT00527293
- Testing
- adjuvant therapy, 3-dimensional conformal radiation therapy, brachytherapy
- Where
- 4 sites in United States
- Volunteers
- 29 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Evaluation of Patients With Breast Cancer Using DCE-MRI, MRS, and Proteomics
RATIONALE: Diagnostic procedures, such as dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI), magnetic resonance spectroscopy (MRS), and tissue proteomics, may help doctors find and diagnose breast cancer and plan the…
- Trial name
- NCT00656604
- Testing
- proteomic profiling, lumpectomy or mastectomy, dynamic contrast-enhanced magnetic resonance imaging
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Stage I Breast Cancer, Stage II Breast Cancer
Acupuncture Pilot Study for Cancer-related Cognitive Function
This study is being done to explore whether acupuncture can improve cognitive difficulties in patients diagnosed with cancer.
- Conditions
- Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer, Stage I Colorectal Cancer
- Trial name
- NCT04007770
- Testing
- Acupuncture, 16 week waiting period + optional Acupuncture
- Where
- 6 sites in United States
- Volunteers
- 48 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Surgery With or Without Lymph Node Removal in Treating Older Women With Stage I or Stage IIA Breast Cancer
RATIONALE: Removing axillary lymph nodes may be effective in stopping the spread of breast cancer cells. It is not yet known if surgery to remove breast cancer is more effective with or without lymph node removal.
- Trial name
- 10-93 (NCT00002528)
- Testing
- tamoxifen citrate, conventional surgery, radiation therapy
- Where
- 21 sites in Australia, Hungary and 7 more
- Volunteers
- 473 people
- Sponsor
- ETOP IBCSG Partners Foundation
Breast Cancer
Radiation Therapy in Treating Women With Stage I or Stage II Breast Cancer
RATIONALE: Radiation therapy may kill any tumor cells remaining after surgery. PURPOSE: Phase I/II trial to study the effectiveness of brachytherapy in treating women who have stage I or stage II breast cancer.
- Trial name
- NCT00002873
- Testing
- brachytherapy
- Where
- 232 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Breast Cancer, Fatigue
Expressive Writing in Improving Quality of Life in Patients With Breast Cancer and Lymphedema
RATIONALE: Expressive writing may help relieve symptoms and improve quality of life in breast cancer survivors with chronic lymphedema.
- Conditions
- Breast Cancer, Fatigue, Lymphedema
- Trial name
- NCT00679185
- Testing
- expressive writing
- Where
- 3 sites in United States
- Volunteers
- 107 people
- Sponsor
- Vanderbilt University
Breast Cancer, Lung Cancer
Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors
RATIONALE: Amifostine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. PURPOSE: This phase II trial is studying how well amifostine works in reducing pain, numbness, tingling…
- Conditions
- Breast Cancer, Lung Cancer, Neurotoxicity, Ovarian Cancer
- Trial name
- NCT00078845
- Testing
- Amifostine
- Where
- 15 sites in United States
- Volunteers
- 24 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Ductal Breast Carcinoma in Situ
Bilingual Breast Cancer Educational Intervention for Hispanic Women With Stage I, Stage II, or Stage III Breast Cancer and Their Families or Caregivers
RATIONALE: Studying quality-of-life in patients having cancer treatment may identify the intermediate- and long-term effects of treatment on patients with cancer PURPOSE: This randomized clinical trial is studying how well an…
- Conditions
- Breast Cancer, Ductal Breast Carcinoma in Situ, Stage I Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT01043003
- Testing
- educational intervention, quality-of-life assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Cancer Survivor, Stage 0 Breast Cancer AJCC v6 and v7
Kindness Interventions in Enhancing Well-Being in Breast Cancer Survivors
Emerging evidence suggests that both extending kindness towards others and self-kindness practices may have beneficial effects on well-being.
- Conditions
- Cancer Survivor, Stage 0 Breast Cancer AJCC v6 and v7, Stage I Breast Cancer AJCC v7, Stage IA Breast Cancer AJCC v7
- Trial name
- NCT03319342
- Testing
- Behavioral Intervention, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 133 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer
Improving Communication With Patients With Breast Cancer
RATIONALE: An education program based on patients' health communication needs may improve patients' overall healthcare experience and sense of control.
- Trial name
- NCT00276822
- Testing
- communication intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma
Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer
This phase II trial studies how well hypofractionated radiation therapy works in treating patients with stage 0-IIB breast cancer.
- Conditions
- Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma, Stage 0 Breast Cancer, Stage I Breast Cancer
- Trial name
- NOVEMBER (NCT03345420)
- Testing
- Hypofractionated Radiation Therapy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Utah
Breast Cancer
Letrozole or Tamoxifen in Treating Postmenopausal Women With Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by reducing the production of estrogen.
- Trial name
- BIG 1-98 (NCT00004205)
- Testing
- letrozole, tamoxifen citrate
- Where
- 3 sites in Denmark, France and 1 more
- Volunteers
- 8,028 people
- Sponsor
- ETOP IBCSG Partners Foundation
Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
Nipple Aspirate Fluid in Detecting Breast Cancer
This trial studies nipple aspirate fluid in detecting breast cancer. Nipple aspirate fluid may better detect breast cancer earlier than current methods used for screening such as mammograms and breast examinations.
- Conditions
- Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8
- Trial name
- NCT03715959
- Testing
- Aspiration of Breast, Biospecimen Collection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center