Clinical trials: Sterility
Covid19
Ultraviolet Germicidal Irradiation on the New Silicone Half-Piece Elastometric Respirators
Since the innovation of our new half- elastometric half-piece respirator, this type of FFR has been used widely in our country. Decontamination methods including ultraviolet C (UVC) germicidal irradiation and 70% alcohol have…
- Trial name
- NCT04749121
- Testing
- UVC Irradiation, Fit test, Tensile strength
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Infertility
The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site
The bioavailability study is intended to evaluate the pharmacokinetic (PK) characteristics and the bioavailability of the two formulations in humans before and after the change of production site, in order to assess the possible…
- Trial name
- NCT06095206
- Testing
- GenSci094
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Infertility
IVF Treatment in Women With Immature Oocytes in Previous Cycle
In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge.
- Trial name
- NCT02368964
- Testing
- GnRH agonist 0.2 mg + hCG 250 mcg, high dose hCG 500 mcg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Female
The Effectiveness and Safety of the Prolonged Down-regulation Protocol for Controlled Ovarian Hyperstimulation
Since the first "tube baby", Louise Brown, was born in the United Kingdom in 1978, many infertile couples have been benefitted from in vitro fertilization and embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03809221
- Testing
- Triptorelin acetate
- Volunteers
- 1,892 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Infertility
Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) Response to Low Dose Clomiphene Citrate in Normally Menstruating Fertile Women
The goal of the study is to quantitatively evaluate pituitary hormone response, follicle stimulating hormone (FSH) and luteinizing hormone (LH), to low doses of clomiphene citrate in normally fertile women.
- Trial name
- NCT01340521
- Testing
- Clomiphene Citrate
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Varicocele, Infertility, Male
Assessment of Seminal Levels of Cystatin C and Endoglin in Infertile Men With Varicocele
Varicocele is a major contributor in male infertility. The improvement of sperm parameters after varicocelectomy supports this contribution.
- Trial name
- NCT04856579
- Testing
- Varicocelectomy
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Benha University
Infertility, Female
Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility
Randomized, controlled, double-blind, three-arm clinical trial in which 75 women will be randomized to treatment with metformin, 75 women to treatment with placebo and 50 women to the observation group.
- Trial name
- METIN (NCT06012682)
- Testing
- Metformin Hydrochloride
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Infertility
Co-incubation of Oocytes With Sperm: Defining the Optimal Incubation Time
The current pilot study aims to evaluate the fertilization rates between sibling oocytes subjected to short incubation (2h) versus overnight incubation (16-20h).
- Trial name
- NCT04627545
- Testing
- 2h exposure to sperm for IVF, overnight exposure to sperm for IVF
- Where
- United Arab Emirates
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Infertility, Aneuploidy
Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection
This is a prospective randomised study of the evaluation of the clinical IVF results after time lapse assisted embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.
- Conditions
- Infertility, Aneuploidy, Chromosome Abnormality
- Trial name
- NCT05545995
- Testing
- embryo selection
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Postmenopausal, Non-lactating
Food Effects on the Relative Bioavailability of Different Dosages of Risedronate
Randomized, open-label, multi-center, 4-treatment, 4-period crossover study. The study will consist of a screening visit, study center admission (preceding Treatment Periods 1, 2, 3, and 4), 4 treatment periods (4 days each), 3…
- Conditions
- Postmenopausal, Non-lactating, Surgically Sterile
- Trial name
- NCT00717145
- Testing
- risedronate
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Healthy
Relation Between Emotional Stress and Infertility
Infertile couples who come for evaluation and treatment in IVF unit could be under psychological stress. Many authors in the past suggested that stress itself is one of the factors that directly influence fecundability rate.
- Trial name
- SFT (NCT02822872)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Infertility
Oocyte Cryopreservation Comparing Fresh and Vitrified Sibling Oocytes
Vitrification is a method to cryopreserve biological specimens that are sensitive to chilling injury such as oocytes and embryos, and it has been employed with increased survival rate and live births (Hong et al., 1999; Kuleshova…
- Trial name
- NCT00986687
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- UConn Health
Endometriosis, Pelvic Pain
Machine Learning for Early Diagnosis of Endometriosis(MLEndo)
The project aims to create a large prospective data bank using the Lucy medical mobile application and collect and analyze patient profiles and structured clinical data with artificial intelligence.
- Conditions
- Endometriosis, Pelvic Pain, Infertility, Female
- Trial name
- MLEndo (NCT06147687)
- Testing
- Self reported data collection
- Where
- 2 sites in Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Infertility, Male
NT-NOA - Novel Treatment of Some Men With Non-Obstructive Azoospermia
This clinical interventional study aims to assess whether treatment with denosumab in combination with letrozole can improve sperm production in infertile men with non-obstructive azoospermia selected by serum anti-mullerian…
- Trial name
- NT-NOA (NCT06706414)
- Testing
- Denosumab (Prolia), Letrozole (Aromatase Inhibitors)
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Martin Blomberg Jensen
Endometriosis Ovaries, Infertility, Female
Assessment of Telomerase Activity in Endometrial Tissue and Serum in Endometriosis Patients
The goal of the study was the detection of telomerase activity in eutopic, ectopic endometrial tissue and in peripheral blood and finding the correlation between the telomerase activity and clinic findings.
- Trial name
- NCT02984774
- Testing
- Cystectomy, Endometrial sampling, Peripheric blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Male Infertility With Severe Oligo-terato-asteno-spermia
Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.
Some animal studies revealed that the pomegranate juice may improve sperm quality in terms of concentration, motility and morphology, as well as in fertilization rate. Minor data is available regarding the influence on male sperm.
- Trial name
- Pomegranate (NCT01918163)
- Testing
- Pomegranate pills
- Where
- Israel
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility Due to Nonimplantation
Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial
To evaluate the effect ofempiricintralipidinfusion therapy on pregnancy outcomes in patient withunexplained recurrentimplantation failure (RIF) undergoIntracytoplasmic sperm injection (ICSI).
- Trial name
- NCT03374163
- Testing
- intralipid 20%
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Infertility
Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes
The purpose of this study is to determine if cryopreservation at the blastocyst stage followed by embryo thaw and transfer is as effective as cryopreservation of bipronuclear oocytes followed by post-thaw extended culture (PTEC)…
- Trial name
- NCT01247987
- Testing
- Blastocyst cryopreservation, Bipronuclear oocyte cryopreservation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
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