Clinical trials: Steroid
Allergic Asthma
Study to Evaluate the Safety and Efficacy TPI ASM8 in Subjects With Asthma
The researchers propose to study the airways of asthmatics given TPI ASM8 for 14 days, and examine the protective effects on allergen-induced bronchoconstriction, hyperresponsiveness and airway inflammation.
- Trial name
- NCT00550797
- Testing
- TPI ASM8
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Syntara
Diabetes Mellitus, Type 1
Islet Transplantation for Patients With Type 1 Diabetes
This protocol will test whether Type 1 diabetes (T1DM) can be reversed in patients with stable renal allografts by islet transplantation.
- Trial name
- NCT00073281
- Testing
- Islet transplantation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hepatitis
Severe Hepatitis Intervention With Emapalumab for Liver Disease
The goal of this study is to see whether a medicine called emapalumab, a monoclonal antibody, is safe and works well for patients aged 1 year and older who have indeterminate severe hepatitis with T-cell activation and have not…
- Trial name
- SHIELD (NCT07744919)
- Testing
- Emapalumab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Healthcare of Atlanta
Alopecia Areata
Excimer Light and Topical Steroid in Treatment of Alopecia Areata
Alopecia areata is a polygenic autoimmune disease causing hair loss, particularly during the anagen phase of hair growth This condition has a lifetime risk of about 2.1% of the world population and the cumulative incidence seems…
- Trial name
- NCT04793945
- Testing
- topical steroid and 308nm-Excimer light therapy
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acute Graft-Versus-Host Disease
A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease.
This is an single-arm, Phase II multi-center study. The purpose of this study is to assess the efficacy and safety of Jaktinib in subjects with Grades II to IV steroid-refractory acute graft-versus-host disease.
- Trial name
- NCT04971551
- Testing
- Jaktinib Hydrochloride Tablets
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Nephrotic Syndrome
Adrenocorticotropic Hormone (ACTH) for Frequently Relapsing and Steroid Dependent Nephrotic Syndrome
In childhood nephrotic syndrome, the kidneys leak protein, causing body swelling and a variety of possible complications such as infection, blood clots, and kidney failure.
- Trial name
- NCT02132195
- Testing
- ACTH
- Where
- 16 sites in United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Treatment of Chronic Obstructive Pulmonary Disease
De-implementing Inhaled Steroids to Improve Care and Safety in COPD
This Quality Enhancement Research Initiative (QuERI) project is designed to determine efficacy and acceptance of an intervention method to provide primary care providers with patient-tailored electronic consults and corresponding…
- Trial name
- DISCUSS COPD (NCT02896257)
- Testing
- Guideline treatment recommendations
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- VA Office of Research and Development
Adenotonsillectomy, Analgesia
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity
The goal of this study is determine if an oral systemic course of steroids is a safe and effective option in lowering pain and complications following adenotonsillectomy in various pediatric age groups.
- Conditions
- Adenotonsillectomy, Analgesia, Surgery
- Trial name
- NCT04879823
- Testing
- Dexamethasone, Ibuprofen, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 222 people
- Sponsor
- David Chi, MD
Cervical Radiculopathy
Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
The main objective of this study is to determine whether interventional treatment (i.e. epidural steroids), conservative therapy, or the combination, is superior for cervical radiculopathy.
- Trial name
- NCT01144923
- Testing
- Gabapentin and/or Nortriptyline, Physical therapy, Epidural Steroid Injections (ESI), Combination treatment
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Johns Hopkins University
Renal Transplantation
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
This study intends to determine whether steroid withdrawal or calcineurin inhibitor withdrawal is superior for graft function and graft survival.
- Trial name
- CISTCERT (NCT00903188)
- Testing
- cyclosporine, Everolimus
- Where
- 5 sites in Belgium
- Volunteers
- 152 people
- Sponsor
- University Hospital, Antwerp
Steroid Anlgesia in Cancer Pain
Oral Prednisolone Effect on Cancer WHO Stepladder Analgesia Protocol
Introduction; World Health Organization (WHO) analgesic ladder; Step I recommends non-opioid analgesics for mild pain. Step II specifies the use of weak opioids for moderate pain.
- Trial name
- NCT04162379
- Testing
- Oral tablet
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Mansoura University
Congenital Adrenal Hyperplasia
Development of Healthcare Transition for Patients With Congenital Adrenal Hyperplasia
The purpose of this study is to implement and evaluate the feasibility and acceptability of a structured healthcare transition program for adolescents and young adults with congenital adrenal hyperplasia (CAH).
- Trial name
- NCT07611786
- Testing
- exposure to healthcare transition protocol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
AIHA - Warm Autoimmune Hemolytic Anemia
Ibrutinib in Steroid Refractory Autoimmune Hemolytic Anemia
This is an open-labeled, single arm, Phase II, two staged study of combination of ibrutinib and rituximab in patients with autoimmune cytopenia and underlying CLL.
- Trial name
- ISRAEL (NCT03827603)
- Testing
- Ibrutinib
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Eugene Nikitin
Cardiovascular Diseases, Heart Diseases
Trial of Pulse Steroid Therapy in Kawasaki Disease--Pediatric Heart Network
The primary endpoint is coronary artery diameter, normalized for body surface area, 5 weeks after randomization. Secondary endpoints include duration of fever, CRP levels, and adverse events.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Infection, Coronary Aneurysm
- Trial name
- NCT00132080
- Testing
- Steroids
- Volunteers
- 199 people
- Sponsor
- Carelon Research
Nephrotic Syndrome in Children
Study of Adrenocorticotropic Hormone on Children With Frequent Relapse or Steroid-dependent Nephrotic Syndrome: a Prospective, Multicenter, Randomized，Open-label Clinical Trial.
Primary nephrotic syndrome accounts for approximately 90% of the total number of nephrotic syndrome in childhood and it is the most common glomerular disease in children.
- Trial name
- NCT06079788
- Testing
- Adrenocorticotrophic Hormone, Steroid
- Where
- 8 sites in China
- Volunteers
- 140 people
- Sponsor
- Mao Jianhua
Steroid-Induced Diabetes, Steroid Induced Hyperglycemia
The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes
TITLE: How GLP-1 Analogues prevent steroid-induced diabetes (The GAPSID Study) DESIGN: A double-blind study evaluating how GLP-1 analogues, compared with metformin, prevent hyperglycaemia in response to a 7-day course of…
- Trial name
- NCT06318442
- Testing
- Semaglutide Oral Product, Metformin Oral Tablet
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pancreas-Kidney Transplantation
Simultaneous Pancreas-kidney Transplantation With Campath Protocol
The purpose of this study is to determine and compare the efficacy of Campath-1H/Tacrolimus versus ATG/Tacrolimus/MMF therapy in conjunction with initial short-term steroids in Type 1-diabetic patients undergoing simultaneous…
- Trial name
- NCT00316810
- Testing
- Alemtuzumab, Rabbit Anti-Human Thymocyte Globulin
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Dr. Claudia Bösmüller
Chronic Pain
A Single Arm, Open-label First In Human Study for Assessing the Safety and Performance of the EpiFinder in Subjects With Clinical Indication for Lumbar Epidural Steroids Injection (ESI)
The EpiFinder device, which is the investigational device in this study, is intended for use in epidural procedures, between a luer syringe and an epidural needle, to give the treating physician a clear indication that the needle…
- Trial name
- NCT04047927
- Testing
- EpiFinder
- Where
- 2 sites in Israel
- Volunteers
- 15 people
- Sponsor
- Omeq Medical
Healthy Volunteers, Doping in Sports
Effect of Tea Consumption on Steroid Profile in Healthy Volunteers
Open label phase I clinical trial in healthy volunteers designed to assess changes on steroid profile after green tea consumption.
- Trial name
- NCT02779361
- Testing
- Green tea
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Sinusitis, Nasal Polyps
Comparison of Nasal Steroids After FESS in CRSwNP
The purpose of this study is to compare intranasal fluticasone spray with budesonide nasal saline rinses in both the upright and head forward positions in patients who have had functional endoscopic sinus surgery (FESS) for…
- Trial name
- NCT02194062
- Testing
- fluticasone nasal spray, Budesonide head upright, Budesonide head forward
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Yale University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.