Clinical trials: Stiffness
Healty, Sedantary Activity
The Effect of Different Exercise Approaches on Passive Mechanical Properties of Hamstring and Quadriceps Muscles, Strength and Jumping Performance
The mechanical characteristics play a crucial role in sustaining daily life activities and facilitating participation in sport activities and exercises demanding a diverse range of motion.
- Conditions
- Healty, Sedantary Activity, Young, Female
- Trial name
- NCT06808919
- Testing
- Whole Body Vibration Exercise, Aerobic Exercise, Strengthening Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uludag University
Cardiovascular Risk Factor, Cardiovascular Diseases
VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study
Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Atherosclerosis of Artery
- Trial name
- NCT04303546
- Testing
- arterial stiffness measurements
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Liver Cell Damage
Elastography in Liver Cell Failure
1. evaluation of degree of spleen stiffness in liver cell failure patient by elastography. 2. correlation of degree of spleen stiffness and patient outcome
- Trial name
- NCT06089785
- Testing
- elastography
- Where
- Egypt
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Omnia Saad Desoky Mohamed
Health
Application of Elbow Manipulation in Archers
The aim of this study was to: (i) assess the impact of maximal muscle strength and stiffness on EMG and Myoton parameters for selected upper limb muscles; and (ii) assess how manipulation of the initial 2-s tension phase, in…
- Trial name
- Manual Therapy (NCT06826300)
- Testing
- Manual therapy
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Asymptomatic Condition
Effect of Osteopathic Technique on Maximum Mouth Opening Width, Masseter Muscle Tone and Stiffness
The purpose of this study is to assess the effect of compression and decompression thecnique on the temporomandibular joint on maximum mouth opening width, masseter muscle tone and stiffness in asymptomatic adults, compared with…
- Trial name
- NCT07670832
- Testing
- Osteopathic Intervention Techniques
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Respiratory Inflammation, Systemic Inflammation
Woodsmoke Exposure and Cardiovascular Function
Air pollution is linked to respiratory and cardiovascular disease. Wood smoke is a common air in many parts of the world and previous studies indicate that wood smoke induce oxidative stress in the respiratory tract.
- Trial name
- NCT01488500
- Testing
- Bronchoscopy
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Spinal Cord Injury
A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences
The general population is aging, today 12% of the United States population is older than 65 and it is estimated that by 2020 the number of people in the United States older than 65 will outnumber children younger than 5.
- Trial name
- NCT03023163
- Testing
- Longitudinal
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Delayed Onset Muscle Soreness (DOMS), Healthy
Posterior Chain Responses to Gastrocnemius DOMS
The goal of this clinical trial is to learn how delayed onset muscle soreness (DOMS) in the calf muscle (gastrocnemius) affects the muscles of the posterior chain and physical performance in healthy young adults.
- Trial name
- NCT07324395
- Testing
- Gastrocnemius DOMS Induction Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ebru Aloğlu Çiftçi
Pudendal Neuralgia- Physiotherapy
Exercise Program in Women With Pudendal Neuralgia
This randomized controlled trial compares a 6-month physiotherapy exercise program versus no structured exercise intervention in women with pudendal neuralgia.
- Trial name
- ELASTIN (NCT07446556)
- Testing
- Pelvic Floor Relaxation Protocol
- Where
- Slovakia
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Comenius University
Vascular Dilation, Arterial Stiffness
Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females
Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males.
- Trial name
- NCT05221905
- Testing
- BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Induced Vaginal Delivery
Can Cervical Stiffness Predict Successful Vaginal Delivery After Induction of Labour?
The purpose of this study is to determine if a new antenatal test of cervical stiffness can be used to predict which patients will have a successful vaginal delivery following an induction of labour.
- Trial name
- CASPAR (NCT05981469)
- Testing
- Cervical Stiffness Assessmenr, Bishop's Score Assessment
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Aging
The Effect of Time-restricted Feeding on Physiological Function in Middle-aged and Older Adults
The purpose of this study is to assess the safety and efficacy of time-restricted feeding (eating within an 8-hour window) for improving physiological function (vascular, motor, cognitive and metabolic function) in healthy…
- Trial name
- NCT02970188
- Testing
- Time Restricted Feeding
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Liver Fibrosis
Development of Predictive Indicators of Homogeneous Propagation of Ultrasound and Elastic Waves During VCTE Examination
This is an European, prospective, interventional, and multicenter exploratory clinical investigation that will take place in 6 French sites and 200 patients will be included (adults and children).
- Trial name
- NCT04747457
- Testing
- Research FibroScan
- Where
- 6 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Echosens
Cystic Fibrosis
Longitudinal Assessment of Exercise Capacity and Vascular Function in Patients With CF
This project is an attempt to understand how Orkambi treatment affects exercise capacity and the function of the arteries in CF patients who are homozygous F508del.
- Trial name
- NCT03338595
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Augusta University
Elevated Blood Pressure, Hypertension
The Effects of Pumpkin Seed Oil Supplementation on Cardiovascular Function in Postmenopausal Women.
Postmenopausal women have a higher prevalence of cardiovascular (CV) disease than age-match men. Growing evidence from rat studies have demonstrated CV-protective effects of pumpkin seed oil (PSO).
- Trial name
- NCT03716960
- Testing
- Pumpkin Seed Oil
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Marymount University
Postmenopausal Disorder, Autonomic Imbalance
Inspiratory Muscle Training X CardioBreath App Effects On Vagal Modulation And Pulse Wave Velocity
Existing data points to relevant beneficial effects of respiratory exercises on cardiovascular health, with special regards to decreases on arterial pressure and improves on autonomic and vascular profiles, though mechanistics of…
- Conditions
- Postmenopausal Disorder, Autonomic Imbalance, Vascular Stiffness
- Trial name
- CardioBreath (NCT03672760)
- Testing
- CardioBreathApp, IMT PowerBreath
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Ageing, Aerobic Exercise
Acute Exercise Effects on Arterial Stiffness and Cardiovagal Modulation in Adults
Background and Gap: The physiological importance of large artery distensibility in cardiovascular function is well-established. Stiffening of central arteries leads to elevated systolic blood pressure (SBP), increased left…
- Conditions
- Ageing, Aerobic Exercise, Resistance Exercise, Combined Exercise
- Trial name
- PUMPING ARTERY (NCT06616428)
- Testing
- Bike group fitness class, Pump Power, Global Training
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Aging, Vascular Stiffness
Restoring Glycocalyx Thickness in Older Adults to Improve Vascular Function
The glycocalyx serves as the interface between flowing blood and endothelial cells, the single cell layer that lines blood vessels, and is crucial for normal blood vessel function.
- Conditions
- Aging, Vascular Stiffness, Endothelial Dysfunction
- Trial name
- RESTORE (NCT06071728)
- Testing
- Endocalyx Pro (Microvascular Health Solutions, US Patent Number: 9943572)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Pregnant Women, First Pregnancy
Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnant Women
Pregnancy causes the development of biomechanical adaptations in the musculoskeletal system, especially in the lumbopelvic region.
- Trial name
- NCT05335330
- Testing
- Evaluation of biomechanics and viscoelastic properties of Thoracolumbar fascia
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey