Clinical trials: Stiffness of Knee
Knee Osteoarthritis, Pain, Joint
Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis
The aim of this clinical trial study is to compare the efficacy of Hyaluronic injection in patients with symptomatic knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Pain, Joint, Stiffness of Knee, Not Elsewhere Classified, Quality of Life
- Trial name
- NCT06279507
- Testing
- Sodium Hyaluronate, Normal Saline, Triamcinolone Acetonide 10mg/mL
- Where
- Thailand
- Volunteers
- 176 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Degenerative Osteoarthritis, Rheumatoid Arthritis
Orthopilot Elite Post-Market Clinical Follow-Up
Prospective, multicenter, observational, comparative clinical trial on the equivalence of two different OrthoPilot® navigation system generations applied for computer-assisted total knee arthroplasty
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Posttraumatic Arthropathy, Instability, Joint
- Trial name
- NCT03817632
- Testing
- Computer assisted primary total knee replacement with OrthoPilot FS101 navigation system and Software 5.1, Computer assisted primary total knee replacement with OrthoPilot Elite navigation system and Software 6.0
- Where
- 3 sites in Germany
- Volunteers
- 217 people
- Sponsor
- Aesculap AG
Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome
Hamstring Strengthening in Hypermobile Conditions
The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
- Conditions
- Hypermobile EDS (hEDS), Hypermobile Ehlers-Danlos Syndrome, Hypermobile Spectrum Disorder, Hypermobility Type Ehlers-Danlos Syndrome
- Trial name
- NCT07626957
- Testing
- Progressive resistance exercise with an emphasis on eccentric hamstring loading.
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Osteoarthritis, Osteoarthritis, Knee
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
The purpose of this study is to evaluate the efficacy of hydrolyzed collagen in osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT05070871
- Testing
- Hydrolyzed Collagen, CalGo
- Where
- 3 sites in Norway
- Volunteers
- 98 people
- Sponsor
- Hofseth Biocare ASA
Knee Replacement Arthroplasty, Fibrosis
Knee Stiffness in Fibrosis Diathesis
At the standard follow-up moment one year after primary TKA for gonarthrosis, all patients will be checked for signs of fibrosis diathesis.
- Conditions
- Knee Replacement Arthroplasty, Fibrosis, Dupuytren's Disease
- Trial name
- NCT02294890
- Testing
- Total knee arthroplasty
- Volunteers
- 60 people
- Sponsor
- University Hospital Pellenberg
Knee Osteoarthritis
The Effect of "Laying on of Hands" in Older Women With Knee Osteoarthritis
Osteoarthritis (OA) is the most common form of chronic degenerative joint disease, as well as the main cause of pain and disability in older persons worldwide.
- Trial name
- NCT02917356
- Testing
- Spiritual laying on of hands (SP), Non-spiritual Laying on of Hands, Control group
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Federal University of Juiz de Fora
Knee Discomfort
Hold-relax and Muscle Energy Techniques in Patients With Post-traumatic Knee Stiffness
The study was conducted to compare the effects of hold-relax and muscle energy technique on pain, range of motion an lower extremity function in patients with post-traumatic knee stiffness.
- Trial name
- NCT07438561
- Testing
- Hold-Relax Technique, Muscle Energy Technique, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee, Quality of Life
Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study
The study hypothesized that it is feasible and safe to use Hatha yoga in older women with knee osteoarthritis (OA), and practicing Hatha yoga regularly will help reduce pain and stiffness, enhance physical function, and improve…
- Conditions
- Osteoarthritis, Knee, Quality of Life, Poor Quality Sleep, Physical Impairment
- Trial name
- NCT01832155
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
Does Joint Immobilization Following Revision Total Knee Arthroplasty Improve Range of Motion Following Surgery?
The goal of this study is to evaluate if knee immobilization for 10 days following revision total knee arthroplasty (rTKA) improves knee joint range of motion at 3 months postoperatively compared to standard of care postoperative…
- Trial name
- NCT07552415
- Testing
- Knee immobilizer, No Knee Immobilizer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Fractures, Stiffness of Knee, Not Elsewhere Classified
Clinical Results After Judet Quadricepsplasty for Post-traumatic Knee Stiffness
The Post-traumatic Extension Contracture of the Knee (PECK) is a common complication following knee traumas. It is characterized by a restricted Range of Motion (ROM), pain, and discomfort in the affected knee.
- Trial name
- NCT06251765
- Testing
- Clinical scores, Range of Motion
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Amputation, Transtibial Amputation - Unilateral
Influence of Prosthetic Foot Stiffness on Transtibial Osseointegrated Bone-Anchored Limb Outcomes
A clinical trial utilizing cross-over study design in which individuals with transtibial amputation using either a bone-anchored limb or standard socket prosthesis will perform activities of daily living with varying prosthetic…
- Conditions
- Amputation, Transtibial Amputation - Unilateral, Bone Anchored Devices, Osseointegration
- Trial name
- TBAL (NCT07263945)
- Testing
- As-prescribed prosthetic foot stiffness, A prosthetic foot that is two prosthetic foot stiffness categories stiffer than the stiffness of the as-prescribed prosthetic foot, A prosthetic foot that is two prosthetic foot stiffness categories softer than the stiffness of the as-prescribed prosthetic foot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Arthroplasty Complications, Fibrosis
Physiotherapy for Arthrofibrosis Following Knee Replacement.
This research aims to develop an optimal physiotherapy intervention for people with arthrofibrosis (stiffness due to scar tissue) after total knee replacement (TKR). We will develop an optimal intervention by conducting: 1.
- Conditions
- Arthroplasty Complications, Fibrosis, Knee Joint Contracture
- Trial name
- ReSTART (NCT05459259)
- Testing
- Interviews and Delphi Survey
- Where
- United Kingdom
- Volunteers
- 145 people
- Sponsor
- University of Nottingham
Post Operative Pain
Comparative Effects of Hold Relax Technique and Mulligan Mobilization in Post Operative Knee Joint
The aim of this study is to investigate the comparative effects of hold relax technique and mulligan mobilization on pain, ROM and function in post operative knee joint.
- Trial name
- NCT05356663
- Testing
- Mulligan Mobilization, Hold Relax
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Osteoarthritis (Knee / Hip), Sarcopenia
Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty
In elderly patients undergoing arthroplasty surgery, postoperative recovery quality is closely related to preoperative physical reserve. Sarcopenia and reduced muscle quality can increase postoperative complications.
- Conditions
- Osteoarthritis (Knee / Hip), Sarcopenia, Postoperative Recovery
- Trial name
- PRE-QoR (NCT07879209)
- Testing
- Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Degenerative Osteoarthritis, Rheumatoid Arthritis
All Polyethylene Tibia-VEGA Kiel
Obligatory Post-Marketing Clinical Follow-up (PMCF) as part of the post marketing surveillance plan for the product under investigation For this PMCF only CE-marked medical devices will be used within their intended purpose and…
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Post-traumatic; Arthrosis, Other Instability, Knee
- Trial name
- APT-VEGA_KI (NCT02756702)
- Testing
- All-Poly
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Aesculap AG
Arthroplasty, Replacement, Knee
Static Progressive Splinting in the Management of Knee Stiffness Following Total Knee Arthroplasty
The purpose of this study is to determine the feasibility and initial efficacy of static progressive splinting for individuals presenting with knee stiffness following total knee arthroplasty (TKA).
- Trial name
- NCT04837872
- Testing
- Multimodal Physical Therapy (MPT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Joint Health, Mobility
A Clinical Trial to Investigate the Efficacy and Safety of a Plant-based Cetylated Fatty Acids (CFA) on Knee Pain and Stiffness in Healthy Adults With Persistent Knee Pain
The goal of this clinical trial is to investigate the efficacy and safety of plant-derived cetylated fatty acids (CFA) on joint health and mobility in adults with persistent knee pain.
- Conditions
- Joint Health, Mobility, Knee Pain
- Trial name
- NCT07695714
- Testing
- Plant-derived cetylated fatty acids (CFA)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Everwell Health
Degenerative Osteoarthritis, Rheumatoid Arthritis
VEGA Prospective Kiel
Voluntary Post-Marketing Clinical Follow-up (PMCF) as part of the post marketing surveillance plan for the product under investigation.
- Trial name
- NCT02802085
- Testing
- VEGA Knee
- Where
- Germany
- Volunteers
- 84 people
- Sponsor
- Aesculap AG
Pain, Pain, Postoperative
Effects of IASTM With and Without CT on Pain, ROM, and Functional Disability in Post-Operative Knee Stiffness Patients
This single-blinded randomized control study aimed to determine the effects of instrumental soft tissue mobilization technique with and without conservative treatment in post-operative knee stiffness patients.
- Conditions
- Pain, Pain, Postoperative, Pain, Joint, Knee Pain Chronic
- Trial name
- NCT06551922
- Testing
- Instrumental Soft Tissue Mobilization Technique with Conservative Treatment, Conservative Treatment
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Stiffness; Spine, Mobility Limitation
Comparison of Active Isolated Stretching Versus Myofascial Release of Knee Joint in Office Workers
"Office workers often spend long hours sitting, which can lead to stiffness and reduced mobility. By studying these two techniques AIS and MFR, we can determine which one is more effective in helping office workers to improve…
- Trial name
- NCT06352450
- Testing
- Active isolated stretching (AIS), Myofascial release (MFR)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Superior University