Clinical trials: Stomach Diseases
Gastro Intestinal Bleeding, Polyps
Nexpowder to Prevent Delayed Bleeding After Endoscopic Resection
Safety and effectiveness of a new hemostatic system to prevent delayed bleeding after endoscopic resection in a selected high-risk population (NEXPOWDER- ENDOHS).
- Trial name
- NEX-ENDOHS (NCT06096948)
- Testing
- NEXPOWDER-ENDOHS
- Where
- 12 sites in Belgium, Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Gastric Cancer
Image-guided Minimally Invasive Robotic Surgery Using Preoperative CT Scan for Gastric Cancer Patients
The purpose of this study is to assess the feasibility of image-guided surgery in patients with early stage gastric cancer using Robotic Surgery with Tile-pro program.
- Trial name
- NCT01338948
- Testing
- preoperative 3D-CT reconstruction
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Yonsei University
Gastro-Intestinal Disorder
Can the SurgInfoBot Improve the Consent Process for Endoscopy? A Randomised Controlled Trial
Human-computer interactions or 'Chatbots' have been utilized in a variety of healthcare settings, including the promotion of positive healthcare behaviors, the deliverance of psychological therapy, and the performance of…
- Trial name
- NCT05159921
- Testing
- Access to an automated conversational agent (SurgInfoBot)
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tallaght University Hospital
Gastric Cancer
Expression of S100A2 and Trefoil Factor Family Members in Epstein-Barr Virus Related Gastric Cancer
The investigators hypothesize that aberrant hypermethylation of tumour suppressor genes is an important mechanism for Epstein-Barr Virus (EBV) - related gastric carcinogenesis, the promoter hypermethylation status and the…
- Trial name
- NCT01100814
- Where
- Singapore
- Sponsor
- National University Hospital, Singapore
Gastric Cancer
Donafenib Monotherapy for Previously Treated Metastatic Gastric Cancer
This open-label, one-center, noncomparative, two-stage phase 1B trial assessed the donafenib in advanced gastric cancer.
- Trial name
- NCT02489214
- Testing
- donafenib tosilate tablets
- Where
- 2 sites in China
- Volunteers
- 13 people
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Breast Cancer, Metastatic Breast Cancer
89Zr-DFO*-Trastuzumab PET in Patients With Gastric or Breast Cancer - a Pilot Study
The goal of this clinical trial is to test a new PET tracer in patients with HER2-positive breast or gastric cancer. This tracer is made of radioactively labeled trastuzumab, and can show where HER2 is present in the body using a…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, HER2-positive Breast Cancer, Gastric Cancer
- Trial name
- HER Image (NCT05955833)
- Testing
- 89Zr-DFO*-trastuzumab PET scan
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Amsterdam UMC, location VUmc
High Risk Population of Gastric Cancer
Application of OE in Diagnosis of EGC
The main purpose of this study is to evaluate application value of OE mode 2 in the diagnosis of early gastric cancer The Secondary purpose is to evaluate application value of OE mode 1 in differentiating the diagnosis of…
- Trial name
- NCT04720521
- Testing
- OE+white light
- Where
- China
- Volunteers
- 2,454 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Gastric Cancer
The Number of Mesogastria Containing Metastatic Lymph Nodes Predicts Gastric Cancer Prognosis
To investigate the impact of the number of mesogastria containing metastatic lymph nodes on the prognosis of gastric cancer.
- Trial name
- NCT06697821
- Testing
- D2＋CME
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Jichao Qin
Stomach Neoplasms
Cisplatin and S-1 With or Without Nimotuzumab in Untreated Advanced Gastric Adenocarcinoma
In this open-label, single-center, small sample size, randomised, parallel-group, controlled study, the investigators aim to assess efficacy and safety of addition of nimotuzumab to CS chemotherapy in patients with previously…
- Trial name
- NCT02370849
- Testing
- nimotuzumab, cisplatin, S-1
- Where
- China
- Volunteers
- 2 people
- Sponsor
- Chinese Academy of Medical Sciences
Stomach Neoplasm
Gastric Cancer' Textbook Oncological Outcome and Tumor Board Performance
The goal of this observational, no-profit, spontaneous, retrospective, monocentric study is to compare surgical and oncologic outcomes in patients affected by gastric cancer before and after the institution of the Tumor Board, a…
- Trial name
- GaC-TOP (NCT06923449)
- Testing
- Multidisciplinary Tumor Board
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gastric Carcinoma
Apatinib Versus Placebo as a Third Line Treatment in Patients With Advanced or Metastatic Gastric Cancer
Apatinib is a tyrosin-inhibitor agent targeting at vascular endothelial growth factor receptor (VEGFR), and it's anti-angiogenesis effect has been viewed in preclinical tests.
- Trial name
- NCT00970138
- Testing
- apatinib tablet
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Fudan University
Stomach Cancer, Gastric Cancer
Adjuvant Chemoradiation Therapy for Gastric or Gastroesophageal Junction Adenocarcinoma
The main purpose of this trial is to determine how well patients with gastric or gastroesophageal junction adenocarcinoma respond to chemotherapy with epirubicin, cisplatin and 5-fluorouracil followed by continuous infusion…
- Conditions
- Stomach Cancer, Gastric Cancer, Gastro-esophageal Junction Cancer
- Trial name
- NCT00215514
- Testing
- Epirubicin, Cisplatin, 5-Fluorouracil (5-FU)
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Dana-Farber Cancer Institute
Gastritis
Clinical Trial to Compare Rebamipide/Nizatidine Combination Therapy With Nizatidine Monotherapy in Patients With Gastritis
The purpose of this study is to compare the Efficacy and Safety of Rebamipide/Nizatidine Combination Therapy with Nizatidine Monotherapy in Patients with Gastritis
- Trial name
- NCT05072938
- Testing
- Mucotra SR Tablet 150mg, Axid Capsule 150mg
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Gastric Cancer
A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis
This study is a single-center, prospective, phase II clinical trial aimed at assessing the impact of HIPEC combined with systemic chemotherapy and immune checkpoint inhibitors on the R0 resection rate in patients with peritoneal…
- Trial name
- NCT06685887
- Testing
- HIPEC, SOX, Immune Checkpoint Inhibitors
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Advanced Solid Tumors, Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Study of INCA 0186 in Subjects With Advanced Solid Tumors
This is an open-label, nonrandomized, multicenter, dose escalation, and dose expansion first-in human (FIH) Phase 1 study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy of INCA00186 when…
- Conditions
- Advanced Solid Tumors, Squamous Cell Carcinoma of the Head and Neck (SCCHN), Gastrointestinal (GI) Malignancies
- Trial name
- NCT04989387
- Testing
- INCA00186, Retifanlimab, INCB106385
- Where
- 32 sites in United States, Austria and 4 more
- Volunteers
- 57 people
- Sponsor
- Incyte Corporation
Gastrointestinal Cancer, Pancreatic Cancer
Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies
The primary objective of this prospective observational study is to characterize the gut and oral microbiome as well as the whole blood transcriptome in gastrointestinal cancer patients and correlate these findings with cancer…
- Conditions
- Gastrointestinal Cancer, Pancreatic Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT05462314
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Viome
Overweight, Obesity
A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become Pregnant
The purpose of this clinical study is to find out if UBT251 is safe and effective to be taken together with medicines, like birth control tablets, and emptying of the stomach in women not able to become pregnant living with…
- Trial name
- NCT07710729
- Testing
- UBT251, Oral contraceptive, Acetaminophen
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Postoperative Complications
Sleeve Gastrectomy as a Standard Bariatric Procedure
This study compared differences in weight loss, comorbidity resolution and complications and reoperations between a recently established sleeve gastrectomy (SG) and prior laparoscopic Rox-en-Y gastric bypass (RYGB).
- Trial name
- NCT05336331
- Testing
- SG or a RYGB
- Where
- Sweden
- Volunteers
- 1,015 people
- Sponsor
- Umeå University
High Blood Glucose
Brown Seaweeds Effect on Glucose Tolerance and Appetite Response
The project is a randomized, 3-way, blinded crossover trial in which 20 healthy, fasted participants consume meals with 30 g of a linear corn starch and 5 g of one of the seaweeds, Laminara digitata or Undaria pinnatifida or a…
- Trial name
- NCT02608372
- Testing
- LD, UP, CTR
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Gastric Cancer
S-1-induced Lacrimal Drainage Obstruction
S-1 is an effective drug in gastric cancer (GC) for palliative chemotherapy in Eastern and Western patients. Recently, S-1 has been also reported to be an effective adjuvant therapy for GC patients who received D2 surgery in…
- Trial name
- NCT01486472
- Testing
- S-1
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Bundang Hospital
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