Clinical trials: Stomatognathic Disease
Nasopharyngeal Carcinoma
Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
Researchers conduct the clinical trial (gemcitabine combined with cisplatin induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine for locally advanced nasopharyngeal carcinoma) to evaluate the safety…
- Trial name
- NCT04522050
- Testing
- Gemcitabine combined with cisplatin induction chemotherapy, concurrent chemoradiotherapy with gemcitabine
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Dental Plaque
Efficacy of Miswak in Oral Hygiene Maintenance
Miswak has been recommended by world health organization for oral hygiene because of its availability, beneficial effect and affordability.
- Trial name
- NCT04561960
- Testing
- Fluoride toothpaste, Toothpaste Product, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Bruxism
In Vivo Comparison of Two Different Occlusal Splints in Bruxism
According to the international consensus, bruxism is a masticatory muscle activity consisting of grinding and clenching while sleep or wakefullness.
- Trial name
- NCT06482060
- Testing
- Stabilization splint
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Enamel Lesions, Dental Caries
Comparison of Different Methods of Enamel Preparation Before Pit and Fissure Sealants
This study concerns the prevention of dental caries by sealing pits and fissures of permanent molars with a photopolymerizable resin.
- Trial name
- NCT02594020
- Testing
- air abrasion, sono abrasion, dental bur
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Maxillary Deficiency
Comparative Results of Maxillary Deficiency Treatment by Fixed Tongue Appliance and Fixed Facemask in Growing Patients
A new fixed appliance will be used to transfer the tongue force during its physiological activity to advance the nasomaxillary complex; this method will be compared with the traditional method which uses a facemask with a fixed…
- Trial name
- NCT00916084
- Testing
- Fixed Tongue Appliance, Fixed Face Mask
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University
Chronic Periodontitis
Atorvastatin in the Treatment of Mandibular Degree II Furcation Defects
ABSTARCT Background: Atorvastatin is an inhibitor of 3-hydroxy-2-methyl-glutaryl coenzyme A reductase. Lately, it has shown to have anti-inflammatory and bone stimulatory effects.
- Trial name
- NCT02386033
- Testing
- Atorvastatin (ATV)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Bell Palsy
EFFECTİVENESS OF PULSED ULTRASOUND TREATMENT ON PATIENTS WITH BELL'S PALSY
Bell's palsy (idiopathic facial palsy) is the most common peripheral lesion of the cranial nerves and the most common mono-neuropathy.
- Trial name
- NCT04412733
- Testing
- Therapeutic Pulsed Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anti-Infective Agents
Special Drug Use Investigation - Assessment of Efficacy and Safety in Treating Secondary Infection of Chronic Respiratory Disease
The objective of this study is to assess the efficacy and safety of Avelox Tablet 400 mg (hereinafter as "Avelox") in treating secondary infection of chronic respiratory disease.It is a local prospective and observational study…
- Trial name
- NCT01690533
- Testing
- Avelox (Moxifloxacin, BAY12-8039)
- Where
- Japan
- Volunteers
- 497 people
- Sponsor
- Bayer
Medication-related Osteonecrosis of the Jaw, Bisphosphonate-related Osteonecrosis of the Jaw
Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ)
The overall purpose of this project is to answer the following clinical question: Among Medication-Related Osteonecrosis of the Jaw (MRONJ) patients, do those who are treated with the Pentoxifylline and Tocopherol (PENTO) regimen…
- Conditions
- Medication-related Osteonecrosis of the Jaw, Bisphosphonate-related Osteonecrosis of the Jaw, Avascular Necrosis
- Trial name
- NCT03040778
- Testing
- Pentoxifylline, Tocopherol
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Temporomandibular Disorder, Myofascial Pain
CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Orofacial Pain, CBD
- Trial name
- NCT05562635
- Testing
- 5% polymer gel with CBD application, 10% polymer gel with CBD application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Oropharynx Cancer
Staying Connected: a Mobile Health Study With the Noona® and Mobili-T® Systems
Mobile health applications are an attractive technological solution that facilitates access to care for patients conveniently and efficiently.
- Trial name
- NCT05368025
- Testing
- Mobili-T/Noona
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Dental Caries
Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initial Lesions
This study will be conducted to assess the effect of different preventive regimens using herbal toothpaste versus fluoride toothpaste on the management of remineralization and caries risk in high caries risk patients.
- Trial name
- NCT04446390
- Testing
- Himalaya complete care toothpaste, colgate cavity protection
- Where
- 2 sites in Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Behcet's Syndrome
Psychological Symptoms in Patients With Behcet's Disease by SCL90-R
To find the overall psychological profile of patients with Behcet's Disease (BD) and compare it with Non-BD patients.patients were checked for psychological symptoms by Symptom Check List 90 Revised (SCL90-R)
- Trial name
- SCL90-R (NCT00699985)
- Where
- Iran
- Volunteers
- 400 people
- Sponsor
- Tehran University of Medical Sciences
Periapical Diseases
Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis…
- Trial name
- NCT02196740
- Testing
- Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste, creosote
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Lin Jiacheng
Pain, Trigeminal Neuralgia
Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
The purpose of this study is to investigate the effects of transcranial magnetic stimulation on pain perception.
- Conditions
- Pain, Trigeminal Neuralgia, Neuropathic Pain
- Trial name
- NCT00349050
- Testing
- laboratory pain assessment, transcranial magnetic stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Mucositis, Xerostomia
Effectiveness of Photobiomodulation Protocols in Radiation-induced Oral Side Effects in H&N Cancer Patients
Head and neck cancer (HNC) are among the most frequent malignancies in the world. The main treatment modalities for HNC are surgical excision, radiotherapy (RT), and chemotherapy (CT).
- Conditions
- Mucositis, Xerostomia, Hyposalivation
- Trial name
- NCT05242991
- Testing
- Photobiomodulation therapy
- Where
- Brazil
- Volunteers
- 132 people
- Sponsor
- Federal University of Rio Grande do Sul
Edentulous Jaw
Mechanical Complications of Full Arch Monolithic Zirconia Restorations to Restore Completely Edentulous Patients Scanned by Horizontal Scan Bodies; A Case Series
the study is concerned with assessing retrospectively the survival and complication rates of monolithic zirconia implant-supported fixed full arch dental restoration scanned using scan ladder scan body over a follow-up period of…
- Trial name
- NCT07662590
- Testing
- scan ladder
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion, Maxillary Expansion
Treatment of Unilateral Posterior Cross Bite in Children
Rapid maxillary expansion and quad-helix are two well established appliances in dentistry used for posterior cross bite treatment.
- Conditions
- Malocclusion, Maxillary Expansion, Pain Children
- Trial name
- NCT04458506
- Testing
- Maxillary expansion
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Malocclusion
Validation of AI-Based Cephalometric Analysis in Orthodontics
This study is designed to evaluate whether artificial intelligence can analyze cephalometric images in orthodontics as a reliable tool for diagnosis and treatment planning.
- Trial name
- AI-CEPH (NCT07315152)
- Testing
- Artificial Intelligence-Driven Cephalometric Analysis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Nasopharyngeal Carcinoma
The Value of Concurrent Chemoradiotherapy for Stage II Nasopharyngeal Carcinoma
The purpose of this study is to verify the role of adding cisplatin chemotherapy to the intensity-modulated radiotherapy (IMRT) for stage II nasopharyngeal carcinoma.
- Trial name
- NCT01187238
- Testing
- cisplatin
- Where
- 3 sites in China
- Volunteers
- 84 people
- Sponsor
- Chinese Academy of Medical Sciences
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