Clinical trials: Streamline or Workflow, Resulting in Reduced or Time
Low Back Pain
A 12-week Pilates Programme for Low Back Pain: Perceived and Actual Outcomes
Pilates has emerged as a prominent exercise therapy gaining recognition among healthcare professionals for its potential benefits in managing low back pain (LBP).
- Trial name
- NCT06395493
- Testing
- Pilates Group, Exercise Group, Control Group
- Volunteers
- 90 people
- Sponsor
- University of Malta
Laser Tattoo Removal
Clinical Evaluation of Tattoo Removal Using a Novel Dual-Wavelength, Dual-Pulse Duration Laser
A single-center prospective, open-label, uncontrolled study in 10 male or female subjects, age 18 to 65 years, who desire laser removal of a tattoo which contains all black ink.
- Trial name
- NCT02431104
- Testing
- 532-nm KTP/1064-nm Nd:YAG Dual-Pulse Duration Laser
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cutera Inc.
Aortic Valve Stenosis
Evaluation of an Intervention to Reduce the Time to Treatment for TAVI Patients
Aortic stenosis (AS) is the most frequent valvulopathy in Western countries. The prevalence of AS is constantly increasing due to the aging of the population.
- Trial name
- TREAT (NCT05237804)
- Testing
- Patient component, Organisational component
- Where
- 2 sites in France
- Volunteers
- 828 people
- Sponsor
- University Hospital, Rouen
Patient Safety
Non-COVID Patient-safety Incidents Reported by Primary Care Professionals in Time of Lockdown: Protocol for a Cross-sectional Descriptive Study
The COVID-19 epidemic is causing a global health crisis. In France, it has imposed a major reorganization of the healthcare system. This emergency reorganization is unprecedented. It involved first, second and third line care.
- Trial name
- PSI-RECORd-XP (NCT04348552)
- Testing
- Primary care professionals reports of potential patient safety incidents, non-COVID-19 related
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Healthy
Efficacy of Ginsana in Improving Half-time Hemoglobin Re-oxygenation in Healthy People
Study to assess the efficacy of ginsana in improving half-time hemoglobin re-oxygenation in healthy, recreational sportspeople and to assess the safety of the product
- Trial name
- NCT02182882
- Testing
- GINSANA
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Postoperative Mortality and Morbidity
Circadian, Weekly and Seasonal Variability of Postoperative Mortality and Morbidity (Zirkadianest)
Mortality is subject to cyclic variability: circadian, weekly, and seasonal. This has been shown for different populations, different diseases and in different countries, but not for surgical patients.
- Trial name
- NCT01903382
- Where
- Germany
- Volunteers
- 247,506 people
- Sponsor
- Charite University, Berlin, Germany
Endoscopy, Colonoscopy
Cecal Intubation Time in Colonoscopy: Prospective Clinical Trial
During colonoscopy, body mass index, waist circumference and waist / hip ratio is the relationship between the cecal intubation difficulty aims to define.
- Trial name
- NCT03002662
- Testing
- colonoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Pulmonary Disease, Chronic Obstructive
Characterisation of 24-hour FEV1-time Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease
The study is intended to characterize the lung function profile of BI1744 in COPD patients where patients will perform pulmonary function tests at regular intervals for 24 hours at the end of a 6 week treatment period.
- Trial name
- NCT00932646
- Testing
- BI 1744 (Olodaterol) Low Dose, BI 1744 (Olodaterol) Medium Dose, Foradil
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Boehringer Ingelheim
Hypotension
Long Time Interval Analysis for Non Invasive Measurement of Cardiac Output
A group of engineers at Michigan State developed a novel waveform analysis technique ("Long Time Interval Analysis" [LTIA]) that attempts to estimate cardiac output non-invasively.
- Trial name
- NCT02473588
- Testing
- Retia Medical Long Time Interval Analysis
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Type 1 Diabetic Nephropathy
The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the most frequent microvascular complications of diabetes mellitus, affecting 25 to 40% of patients with type 1 diabetes (T1DM).
- Trial name
- NCT06115460
- Testing
- oral sitagliptin supplementation
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Pregnancy Related
Endometrial Leucocytes Around the Time of Embryo Implantation in Women Undergoing in IVF-ET
Uterine natural killer (uNK) cells have been implicated to play a role in female reproductive performance. Serval studies showed an increased uNK cell density in the endometrium of women with reproductive failure.
- Trial name
- NCT04079959
- Testing
- endometrial biopsy
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
Type2Diabetes
TRE in Type 2 Diabetes (See Food Study 3)
Hyperglycemia in patients with Type 2 Diabetes Mellitus is initially treated with metformin coupled with intentional caloric restriction, which is difficult to sustain due to multiple barriers, including acquiring the necessary…
- Trial name
- SFS3 (NCT05290246)
- Testing
- Time restricted eating, Caloric reduction
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Advanced Cancer
A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
The purpose of this study is to test the effectiveness and safety of various nivolumab combinations compared to nivolumab and ipilimumab in participants with advanced kidney cancer
- Trial name
- FRACTION-RCC (NCT02996110)
- Testing
- Nivolumab, Ipilimumab, Relatlimab
- Where
- 32 sites in United States, Australia and 4 more
- Volunteers
- 182 people
- Sponsor
- Bristol-Myers Squibb
Diabetes Mellitus, Type 2, Circadian Rhythm
Circadian Rhythm and Metabolic Effects of Exercise
Physical exercise is efficacious in controlling blood glucose levels in individuals with Type 2 diabetes. An individual's exercise capacity and ability to utilize glucose as an energy source oscillates throughout the day.
- Conditions
- Diabetes Mellitus, Type 2, Circadian Rhythm, Glycemic Control
- Trial name
- HITMet (NCT05115682)
- Testing
- High-intensity Intermittent Exercise
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Aerosol Therapy, Asthma
Evaluation of Time-Sensitive Nebulization Mode Converter
This study utilizes a randomized crossover design to evaluate and compare the clinical and technical efficacy of different nebulization modes for aerosol drug delivery.
- Trial name
- NCT07633223
- Testing
- Cross-over Nebulization Modes Comparison System
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Metabolic Syndrome
Effects of Restricted-time and Psychochrononutritional Feeding in People With Metabolic Syndrome
Metabolic syndrome is a cluster of risk factors, including abdominal obesity, high blood pressure, high triglycerides, and insulin resistance, that increase the risk of developing type 2 diabetes and cardiovascular disease.
- Trial name
- PSICRONUT (NCT07389603)
- Testing
- Time restricted eating, Psychochrononutritional intervention
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- University of Guadalajara
Carcinoma Breast Stage I, HER2 Positive Breast Cancer
Pre Operative Trastuzumab in Operable Breast Cancer
Background Information and Rationale: Trastuzumab is a humanized monoclonal antibody that acts extracellularly on the erbB-2 receptor.Trastuzumab is a recombinant humanized IgG1 monoclonal antibody against the human epidermal…
- Trial name
- NCT01785420
- Testing
- Trastuzumab
- Where
- India
- Volunteers
- 1,100 people
- Sponsor
- Dr Rajendra A. Badwe
Bimaxillary Protrusion
Evaluation of Treatment Duration of En-masse Versus Two Steps Retraction in Patients Having Maxillary Protrusion
Brief summary: there's a scarcity in literature concerning time needed to retract anterior segment following premolars extraction.
- Trial name
- NCT04921579
- Testing
- En masse retraction, Two-Step retraction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Sepsis
The Influences of Early Mobilization on Myokines, Body Composition and Outcomes in ICU Septic Patients
the investigators' preliminary data revealed that early physical therapy in patients with sepsis in ICU could promote recovery of function (liver and kidney) and decrease the length of stay in hospitalization.
- Trial name
- NCT06061224
- Testing
- early mobilization (physical therapy)
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia
Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study
Esophageal atresia (EA) is one of the most common gastrointestinal congenital anomalies that affects 1 in 2500 to 1 in 4000 live births.
- Conditions
- Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
- Trial name
- BITES (NCT07100379)
- Testing
- Endoscopic Balloon Dilation
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital