Clinical trials: Stress, Systemic
Child, Only, Essential Hypertension
Juvenile Essential Arterial Hypertension and Vascular Function
The main goal of this study is to investigate the association of the juvenile essential arterial hypertension with systemic micro- and macrovascular reactivity and cerebral vascular function, and to examine the potential impact…
- Trial name
- NCT05109013
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Endothelial Dysfunction
The Association Between Food Timing and Composition on Gastrointestinal Injury, Stress Hormone and Gastrointestinal Complains.
The study aimed to check the influence of timing and composition of diet on markers of gut injury, endotoxemia and stress.
- Trial name
- NCT06403241
- Testing
- 2000 meter ergometer test
- Where
- Poland
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Oxidative Stress, Endothelial Dysfunction
Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3
The purpose of the study is to see how two classes of blood pressure medications,angiotensin-converting enzyme inhibitors (Ace inhibitors) and angiotensin receptor blockers (ARBs), differ in their long term effects on certain…
- Trial name
- NCT00878969
- Testing
- valsartan (ARB), ramipril (ACE inhibitor)
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder
Prevention of Mental Health Problems in People Exposed to a Recent Highly Stressful Event.
This project evaluates the effectiveness of three intervention models for the prevention of mental health problems in people who have suffered a recent highly stressful event, through an experimental design, with a control group…
- Conditions
- Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT04314115
- Testing
- Mindfulness, Systemic therapy, Cognitive behavioral therapy and positive psychology
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas, Chile
Stress, Psychological, Mental Health Wellness
Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families
The purpose of this study is to evaluate a new, community-based, group intervention called FIESTA (Familias Inmigrantes Empoderándose contra eStrés Tomando Acción) to understand how well it helps Latinx immigrant families deal…
- Trial name
- NCT05991739
- Testing
- Familias Inmigrantes Empoderándose contra eStrés Tomando Acción (FIESTA)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Glucose, High Blood, Inflammatory Response
Foodprint 1.0: Physiological Acute Responses After Consumption of Confectionary Products
The composition of a food or a meal consumed plays an important role in the rate of postprandial endocrine and metabolic response, especially if high in fats, sugars and total energy content and a reduction in its entity is…
- Conditions
- Glucose, High Blood, Inflammatory Response, Oxidative Stress, Endotoxemia
- Trial name
- FP1 (NCT03972878)
- Testing
- control snack, control cream, cream version 1
- Where
- Italy
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Parma
Discrimination, Racial, Stress Physiology
Oklahoma Study of Native American Pain Risk III: Stress and Resilience
The goal of this observational study is to learn about the relationship between environmental structural racism and discrimination and chronic pain risk in Native American adults. The main questions it aims to answer are: 1.
- Conditions
- Discrimination, Racial, Stress Physiology, Pain
- Trial name
- OK-SNAPIII (NCT05723081)
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Sepsis, Oxidative Stress
Sepsis and Thiol-Disulfide Balance in Emergency Department
The aim of this study was to determine the effectiveness of thiol-disulfide homeostasis in predicting diagnosis and mortality in sepsis patients, and to compare it with other inflammatory markers.
- Trial name
- NCT07134868
- Testing
- Thiol- Disulfide Blood Sample Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Hepatic Fatty Acid Metabolism, Systemic Insulin Resistance
The Metabolic Effects of a High Fructose Versus a High Glucose Diet in Overweight Men
Dietary consumption of fructose has increased by nearly 50% since 1960. A high fructose diet (HFrD) results in greater visceral adiposity and systemic insulin resistance than a high glucose diet.
- Conditions
- Hepatic Fatty Acid Metabolism, Systemic Insulin Resistance, Oxidative Stress, Cardiovascular Status
- Trial name
- NCT01050140
- Testing
- high sugar diet
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Depression, Systemic Lupus Erythematosus
Intervention to Improve Quality of Life in African American Lupus Patients
The goal of the proposed project is to enhance the Principal Investigator's research ability to conduct behavioral interventions for people with lupus.
- Trial name
- IQAN (NCT01837875)
- Testing
- Chronic Disease Self-Management Program (CDSMP), Mail-delivered arthritis kit, Support group
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Alcohol Dependence
The Impact of Heavy Alcohol Use on Saliva and Oral Health
Background: People with alcohol use disorder (AUD) have a higher rate of dental and gum disease. Poor oral health can increase the risk of other diseases, such as diabetes and stroke.
- Trial name
- NCT06684483
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stress Resilience, Systemic Inflammation
Oral Supplementation With 1 mg of KGA-10 Daily (a Novel Environmentally-derived Mycolicibacterium) for Stress, Sleep, and Inflammation
The goal of this clinical trial is to learn if a novel strain of heat-killed Mycolicibacterium that is being considered by the International Code of Nomenclature of Prokaryotes (ICNP) as candidate species and type strain…
- Conditions
- Stress Resilience, Systemic Inflammation, General Wellbeing, Sleep Quality
- Trial name
- NCT07604038
- Testing
- Mycolicibacterium petrae KGA-10 (heat-killed)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Kioga Inc.
Subclinical Cardiovascular Impairments, Obstructive Sleep Apnea Syndrome
Cardiovascular Impairments and Obstructive Sleep Apnea Syndrome
Which are the anthropometric parameters and/or of severity of the syndrome of apnea of sleep (SAS) which make it possible to anticipate occurred of vascular anomalies, anatomical and/or functional precociously found among…
- Trial name
- INFRASAS (NCT01089257)
- Where
- 3 sites in France
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cardiometabolic Risk, Abdominal Obesity
Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention
The aim of the study is to evaluate the synergistic effects of daily consumption of food products fortified with bioactive components (fibres, polyphenols, omega-3, Slow Digestible Starch) for 9 weeks, compared to the daily…
- Trial name
- SINFONI (NCT04190706)
- Testing
- bioactive components fortified food products intake (biscuits and cookies), control food products intake (biscuits and cookies)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Analgesic Effects, Systemic Stress Response
Bilateral Ultrasound Guided Pectoralis Nerve Block Induces Hemodynamic Stability With Reducing Systemic Stress Response for Off-pump Coronary Artery Bypass Graft
Opioids used in attenuation of the neuroendocrine stress response in patients undergoing off-pump coronary artery bypass graft (OPCAB) it produces predictable satisfactory analgesia and sedation but with side effects such as…
- Conditions
- Analgesic Effects, Systemic Stress Response, Hemodynamic Stability
- Trial name
- NCT03734848
- Testing
- Bilateral Ultrasound Guided Pectoralis Nerve Block.
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Chronic Stress, Systemic Inflammation
Assessing the Feasibility of Multi-modal Biosensing for Monitoring Mobility and Cognition in Older Adults
Current health devices often overlook older users, who may face both health challenges and technology barriers. We are investigating the feasibility of wearable sensors to track posture, heart rate, and breathing, alongside a…
- Conditions
- Chronic Stress, Systemic Inflammation, Mobility and Independence
- Trial name
- NCT07217951
- Testing
- Eutectogel Sensors and Microneedle Patches
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tufts University
LMA Versus Mgso4 in Attenuating Stress Response During Emergence of Supratentorial Tumours Patients
A Comparative Study Between Laryngeal Mask Airway and Magensium Sulphate in Attenuating Systemic Stress Response During Emergence of Patients Undergoing Supratentorial Tumours.
To evaluate the efficacy of replacement of ETT with LMA and administration of Magnesium sulphate at the end of the surgery in attenuating systemic stress response during emergence of patients undergoing supratentorial tumours
- Trial name
- NCT03406403
- Testing
- Laryngeal mask airway, Magensium sulphate, Control group (closure of anesthetics)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lung Function, Heart Rate Variability
Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers
Introduction: Non-mechanized sugar cane harvesting preceded by burning, an important and prevalent professional activity of agribusiness segment of the Brazilian economy, exposes workers and people of neighboring towns to high…
- Conditions
- Lung Function, Heart Rate Variability, Oxidative Stress, Systemic Inflammatory Response
- Trial name
- NCT01371188
- Where
- Brazil
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Hypoxemia
Effects of Acute Intermittent Hypoxia on Brain Function Imaging and Systemic Inflammation
Effects of acute intermittent hypoxia on brain function imaging and systemic inflammation Patients with obstructive sleep apnea (OSAS) may have neurological cognitive impairment. The reason is not clear.
- Trial name
- NCT03453697
- Testing
- acute intermittent hypoxia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Corneal Endothelial Cell Loss, Ozone Therapy
Effect of Systemic Ozone Therapy on Corneal Endothelium
This study evaluates the safety of systemic ozone therapy on the corneal endothelium, a vital non-renewable tissue that maintains corneal transparency.
- Trial name
- OZON-CORNEA (NCT07718100)
- Testing
- Systemic Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University