Clinical trials: Stress Disorder, Post-Traumatic
Substance Use Disorder, Posttraumatic Stress Disorder
Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults
The purpose of the study is to determine the safety and efficacy of an integrated treatment for substance abuse and posttraumatic stress disorder for young adults.
- Trial name
- NCT02667119
- Testing
- Prolonged Exposure with Contingency Management, Standard Care
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- UConn Health
Acute Stress Disorder, Post Traumatic Stress Disorder PTSD
Assessment of the Preventive Effect of Defusing on Traumatic Kindling
The exposure to a potential traumatic event (PTE) is common in the general population. This exposure may lead to psychiatric disorders such as acute stress disorder (ASD) and post-traumatic stress disorder (PTSD).
- Trial name
- PREDEKIT (NCT07850193)
- Testing
- Defusing, Psychological First Aid (PFA)
- Where
- 4 sites in France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Posttraumatic Stress Disorder
Comparing Virtual Reality Therapy to Usual Treatment for PTSD
Combat related Posttraumatic Stress Disorder (PTSD) is the most common chronic psychiatric disorder in the veteran population. Unfortunately, outcome studies of VA PTSD programs have failed to show efficacy.
- Trial name
- NCT00167804
- Testing
- Virtual Reality Exposure
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Post Traumatic Stress Disorder, Adjustment Disorder
Psychological First Aid With Children in a High Risk Group - a Repeated Single Case Design
The purpose of this pilot-study is to evaluate a cognitive behavioral method "Psychological First Aid" used with a group of children (11-16 years) in high risk of developing psychological problems.
- Trial name
- NCT01612104
- Testing
- Psychological First Aid
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- NORCE Norwegian Research Centre AS
Alcohol Abuse, Post-Traumatic Stress Disorder
Pilot Evaluation of the VetChange Mobile App for Veterans With PTSD Who Engage in Problem Drinking
Concept: Alcohol misuse is common among Veterans with PTSD. It has been proposed that this high comorbidity is the result of "self-medication," with alcohol being used to alleviate common PTSD symptoms (e.g., hyperarousal, sleep…
- Trial name
- NCT03208738
- Testing
- VetChange, web-based drinking assessment and feedback tool (AFT)
- Volunteers
- 280 people
- Sponsor
- Eric Kuhn
Traumatic Brain Injury, Posttraumatic Stress Disorder
Telephone Delivery of Cognitively Augmented Behavioral Activation (CABA)
Traumatic brain injury (TBI) is highly prevalent and frequently comorbid among Veterans and Service Members. Many of these individuals sustain more than one TBI over the course of their military careers, often with little…
- Trial name
- Tele-CABA (NCT04200976)
- Testing
- Tele-CABA, Usual Care
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Portland VA Medical Center
Posttraumatic Stress Disorder, Combat Disorders
An Open-Trial of Web-Prolonged Exposure (Web-PE) Among Active-Duty Military
It is urgent to make evidence-based treatments (EBTs) for military personnel readily accessible in order to meet the growing demand for effective and efficient treatment for posttraumatic stress disorder (PTSD) in a timely…
- Trial name
- NCT03337750
- Testing
- Web-PE Therapy
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Pennsylvania
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Postintensive Care Syndrome, Family Members
Family Support Intervention in Intensive Care Units
Background: Family members of critically ill patients face considerable uncertainty and distress during their close other's intensive care unit (ICU) stay, with about 20-60% of family members experiencing post-traumatic distress…
- Conditions
- Postintensive Care Syndrome, Family Members, Quality of Life, Depression, Anxiety
- Trial name
- FICUS (NCT05280691)
- Testing
- Family Support Intervention (FSI)
- Where
- 12 sites in Switzerland
- Volunteers
- 885 people
- Sponsor
- Rahel Naef
Post-traumatic Stress Disorder
Effectiveness of a Brief Intensive Trauma Treatment for Adolescents With (s)PTSD: a Multi-center RCT
The primary objective of this study is to examine the effectiveness of a Brief Intensive Trauma Treatment (BITT) for adolescents with (s)PTSD.
- Trial name
- NCT06143982
- Testing
- Brief Intensive Trauma Treatment
- Where
- 3 sites in Bonaire, Saint Eustatius and Saba , Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cesarean Section, Delivery; Trauma
Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study
Some patients who undergo cesarean section under spinal or epidural anesthesia can experience severe pain. Some patients who experience this kind of pain can experience symptoms of post-traumatic stress disorder (PTSD) after…
- Trial name
- EAGLET-CS (NCT07334418)
- Testing
- General anesthetic, Intravenous anesthetic
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Pennsylvania
PTSD, Alcohol Use Disorders
Integrative Risk Reduction and Treatment for Teen Substance Use Problems and PTSD
Adolescents receiving RRFT and their caregivers will report significantly fewer substance use problems (quantity of use, frequency of use, and abuse symptoms) during treatment and follow-up than control adolescents who receive…
- Conditions
- PTSD, Alcohol Use Disorders, Substance Use Disorders
- Trial name
- RRFT (NCT01751035)
- Testing
- Risk Reduction through Family Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
Intensive Care Pediatric
Experiences Reported by Siblings of Children Hospitalized in the PICU
The care for a child in pediatric intensive care is recognized as a traumatic experience for the patient and their entourage. The needs and feelings of parents are relatively well supported in the literature.
- Trial name
- SIBCARE (NCT06664333)
- Testing
- Semi-structured interviews
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PTSD
IPT-A for Adolescents With PTSD Symptoms
In the present study, the investigators propose to 1) adapt Interpersonal Psychotherapy for Adolescents (IPT-A) as an intervention for adolescents who report elevated symptoms of posttraumatic stress disorder (PTSD) and/or meet…
- Trial name
- NCT03795818
- Testing
- Interpersonal Psychotherapy for Adolescents
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- New York State Psychiatric Institute
Psychological Stress, Anxiety
Mindfulness Training in U.S. Army Cohorts
This project aims to contextualize delivery of mindfulness training to U.S. Army personnel, evaluate its effectiveness on measures of executive functions and psychological well-being, and determine best practices for its delivery.
- Conditions
- Psychological Stress, Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT03310112
- Testing
- 4-week MBAT, 2-week MBAT
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Posttraumatic Stress Disorder, Depression
Efficacy of Narrative Exposure Therapy (NET) in Treating Women After Human Trafficking or Forced Prostitution
The purpose of this study is to perform an evaluation of a trauma-focused short-term intervention (Narrative Exposure Therapy; Schauer, M., Neuner, F.
- Conditions
- Posttraumatic Stress Disorder, Depression, Dissociation
- Trial name
- NCT00717548
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Konstanz
Post-traumatic Stress Disorder (PTSD)
Discontinuing Psychotropic Medication Before Psychotherapy for PTSD
Post-traumatic stress disorder (PTSD) is commonly treated with trauma-focused psychotherapy, including prolonged exposure therapy and eye movement desensitization and reprocessing (EMDR).
- Trial name
- NCT07802158
- Volunteers
- 100 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Anxiety
Transcranial Alternating Current Stimulation (tACS) for the Treatment of Anxiety in Veterans: An Open-Label Pilot Study
Transcranial alternating current stimulation (tACS) in a wearable brain stimulation device that delivers a low intensity, pulsed, alternating current via scalp electrodes.
- Trial name
- NCT07288008
- Testing
- Transcranial alternating current stimulator
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Birmingham VA Health Care System
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