Clinical trials: Stress Disorder, Post-Traumatic
Opioid-use Disorder, Addiction
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses
Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental…
- Conditions
- Opioid-use Disorder, Addiction, Depression, Post-traumatic Stress Disorder
- Trial name
- CLARO (NCT04559893)
- Testing
- Collaborative Care
- Where
- 16 sites in United States
- Volunteers
- 729 people
- Sponsor
- RAND
Post Traumatic Stress Disorder
eTMS for Veterans and First Responders With PTSD
A battery of physiological and behavioral data will be collected before and after application of eTMS. Participants will be veterans or first responders diagnosed with PTSD.
- Trial name
- NCT06294106
- Testing
- Electroencephalogram personalized Transcranial Magnetic Stimulation (eTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Polytechnic Institute and State University
Insomnia, Post Traumatic Stress Disorder
Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-CBTi Study)
The COVID-19 pandemic has resulted in increased workload and concerns about personal and family safety for frontline healthcare workers (HCWs), which can lead to decreased well-being and worsening mental health.
- Conditions
- Insomnia, Post Traumatic Stress Disorder, Anxiety Disorders, Depression
- Trial name
- HCW-CBTi (NCT05816304)
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia (dCBTi)
- Where
- 2 sites in Canada
- Volunteers
- 366 people
- Sponsor
- University Health Network, Toronto
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Post-Traumatic Stress Disorders, Anxiety
fMRI in Posttraumatic Stress Disorder (PTSD) During Working Memory Updating
Neuropsychological studies investigating trauma-exposed and posttraumatic stress disorder (PTSD) subjects have generally underlined the significantly poorer performance of tasks that require attention, concentration, and verbal…
- Conditions
- Post-Traumatic Stress Disorders, Anxiety, Amnesia, Dissociative
- Trial name
- METRAPI (NCT00288314)
- Testing
- Magnetic Resonance Imaging, Functional
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Posttraumatic Stress Disorder
A Pilot Exercise Study for PTSD in Women Veterans
The overall aim of this pilot feasibility study is to determine if 12-week moderate intensity exercise can safely alleviate posttraumatic symptoms in premenopausal women veterans. Specific aims of the study are to; 1.
- Trial name
- NCT01892033
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- North Texas Veterans Healthcare System
Post-Traumatic Stress Disorder
Treating People With Post-Traumatic Stress Disorder With Cognitive Behavioral Therapy for Insomnia
This study will test the effectiveness of cognitive behavioral therapy for insomnia in treating sleep disturbances in people with post-traumatic stress disorder.
- Trial name
- NCT00881647
- Testing
- Cognitive Behavioral Treatment for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Efficacy of Internet-delivered Trauma-focused CBT for Young People With PTSD
The goal of this clinical trial is to compare therapist-guided internet delivered trauma-focused cognitive behavior therapy (CBT) to an active control condition comprising therapist-guided internet delivered cognitive behavioral…
- Trial name
- NCT06185244
- Testing
- Therapist-supported internet-delivered trauma-focused CBT, 12 weeks of therapist-supported internet-delivered psychoeducation and stress management/relaxation for both the youth and the care giver.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
Stress Disorders, Post-Traumatic, Depression
Veteran Health Study
The purpose of The Veteran Health Study (CSP #569) is to better understand the mental and physical health of veterans as they get older.
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Diabetes, Cardiovascular Disease
- Trial name
- NCT01175629
- Where
- United States
- Volunteers
- 7,568 people
- Sponsor
- US Department of Veterans Affairs
Posttraumatic Stress Disorder, Depression
A Randomized Controlled Clinical Trial With Orphans and Widows Who Experienced the Rwandan Genocide
In the framework of the epidemiological study, local psychologists are trained in Butare in carrying out diagnostic interviews with orphans and widows who experienced the Rwandan genocide.
- Conditions
- Posttraumatic Stress Disorder, Depression, Prolonged Grief Disorder
- Trial name
- NCT00553956
- Testing
- Narrative Exposure Therapy/Interpersonal Psychotherapy
- Where
- Rwanda
- Volunteers
- 150 people
- Sponsor
- University of Konstanz
Mental Health, Psychological Trauma
Pathway-Matched Resilience-Oriented Therapy in Rwanda
This pragmatic, pathway-stratified, cluster-randomized waitlist-controlled trial evaluated Resilience-Oriented Therapy (RoT), a culturally adapted group-based psychosocial intervention for post-genocide Rwanda.
- Conditions
- Mental Health, Psychological Trauma, Stress Disorders, Post-Traumatic, Depression
- Trial name
- RoT-CRT (NCT07621731)
- Testing
- Resilience-Oriented Therapy - Emotion-Regulation Variant, Resilience-Oriented Therapy - Identity-Development Variant, Resilience-Oriented Therapy - Behavioural Self-Management Variant
- Where
- 5 sites in Rwanda
- Volunteers
- 427 people
- Sponsor
- Alexandros Lordos, PhD
Opioid Use Disorder, Intimate Partner Violence (IPV)
Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery
Using a hybrid type 1 effectiveness-implementation approach, this study aims to evaluate the impact of a novel stepped care model ("PCT+2HOPE") versus treatment as usual (TAU) on increasing retention in community-based medication…
- Conditions
- Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
- Trial name
- STRONGER (NCT07115030)
- Testing
- PCT+2HOPE
- Where
- 3 sites in United States
- Volunteers
- 532 people
- Sponsor
- Yale University
PTSD
Peer-Delivered Whole Health Coaching for Veterans With PTSD
The investigators are evaluating a service called peer-delivered Whole Health Coaching to understand how it can help Veterans with PTSD.
- Trial name
- NCT03364192
- Testing
- Whole Health Coaching
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Insomnia
CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
This study is a prospective two-arm, single blind randomized controlled trial design to compare the clinical effectiveness of telemedicine-delivered, 6-session, standardized cognitive behavioral therapy for insomnia (CBT-I) and…
- Conditions
- Traumatic Brain Injury, Insomnia, Depression, Post-traumatic Stress
- Trial name
- NCT05663034
- Testing
- Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- 5 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Neuropathic Pain, PTSD
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants.
- Trial name
- NCT06414356
- Testing
- Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Margaux M. Salas, PhD
Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder
Back on My Feet: Emotional Recovery From Fall Injury
We will compare two programs that are designed to help older adults who have had fall injuries manage anxiety and improve their level of functioning.
- Conditions
- Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder, Fear of Falling
- Trial name
- NCT01998945
- Testing
- Exposure-based Cognitive Behavioral Therapy, Relaxation Training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
PTSD, Suicidal Ideation
Experiential Avoidance in Combat Veterans With and Without Posttraumatic Stress Disorder
This study plans to examine if symptoms of PTSD affect how Veterans who have served in combat think and react to certain information, and whether or not this has an influence on suicidal thoughts.
- Trial name
- NCT01652430
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Stress Disorders, Post-Traumatic, Depression
Managing Sleep Symptoms and Modifying Mechanisms of Traumatic Stress
The primary purpose of this study is to test whether and how cognitive-behavioral therapy for insomnia (CBTi), a well-supported and highly effective insomnia treatment, may directly improve Posttraumatic Stress Disorder (PTSD)…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Sleep
- Trial name
- NCT01743339
- Testing
- Cognitive Behavioral Therapy, Control
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Rochester
Acute Stress Reaction
Promoting Improved Functioning Among People Experiencing Stressful Situations
The iCOVER intervention was developed to rapidly restore functioning in individuals experiencing an Acute Stress Reaction (ASR). iCOVER is undergoing widespread adoption but has not been tested for efficacy.
- Trial name
- iCOVER (NCT06482567)
- Testing
- iCOVER, Physical Presence with Reassurance
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders
Body Therapy for War Veterans With Post Traumatic Stress Disorder (PTSD)
The present study is a randomized, controlled trial that compares a certain type of body therapy, called ManuVision, to treatment as usual (TAU) in war veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Behavioral Symptoms, Depression
- Trial name
- NCT03777800
- Testing
- Body therapy, Treatment as usual
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- University of Southern Denmark
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