Clinical trials: Stress Fracture
Stress Reaction, Opioid Use
Effect of Fentanyl on Main Opioid Receptor (OPRM1) on Human Granulosa Cells.
Opioids is known that produce not only analgesia but also hyperalgesia through activation of central glutaminergic system-GABA. At the same time, recently it was found that the main opioid receptor (OPRM1) is present on human…
- Trial name
- NCT03248076
- Testing
- Fentanyl Citrate
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Papanicolaou Hospital
Cesarean Section
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a safer method than general.
- Trial name
- NCT03067896
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Normal Subjects
Acute Effects of Artificial Sweeteners or Sugar on Hemodynamic and Metabolic Stress Responses
This exploratory study aims at investigating the acute effects of artificially sweetened and sugar beverage consumption (as compared to water consumption) on acute hemodynamic and metabolic stress response.
- Trial name
- EduStress (NCT02973334)
- Testing
- Ingestion of artificially-sweetened beverages, Ingestion of sugar-sweetened beverages, Ingestion of water
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Tibial Stress Fracture
Effects of Footstrike Transition on Tibial Stress Fracture Risk
Biomechanical literature suggests that runners who utilize a mid or forefoot strike pattern may suffer from a reduced incidence of chronic injuries compared to a rearfoot strike.
- Trial name
- NCT05786079
- Testing
- Footstrike modification, Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Renal Transplant Donor of Left Kidney
Quadratus Lumborum Block Versus Epidural for Laparoscopic Nephrectomy Kidney Donor
This study aimed to compare Quadratus Lumborum Block to Epidural on Stress Response and Perioperative Cellular Immunological Function of Laparoscopic Nephrectomy Kidney Donor
- Trial name
- NCT03520205
- Testing
- Quadratus Lumborum Block, Continuous Epidural
- Where
- Indonesia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Stress Reaction, Sexuality
Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women
This project will test the ability of brief self-compassion training to attenuate physiological and subjective responses to induced stress among sexual minority women, transgender people, and nonbinary people.
- Conditions
- Stress Reaction, Sexuality, Compassion
- Trial name
- NCT05949060
- Testing
- Compassion Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Stress, Acute Stress Reaction
Impact of Repeated Virtual Reality Training on Markers of Stress
The purpose of this study is to examine whether repeated exposure to an active shooter or target practice virtual reality (VR) scenario alters physiological and psychological stress responses over time.
- Conditions
- Stress, Acute Stress Reaction, Virtual Reality, Active Shooter
- Trial name
- NCT07770880
- Testing
- Active Shooter, Target Practice
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Texas State University
Stress Reaction
Validity for Stress Reduction of Virtual Reality Intervention
The purpose of this study is to verify the effect of virtual reality (VR) intervention on stress reduction for workers. After inducing stress by the Socially Evaluated Cold Pressure Test (SECPT), Investigators should explore…
- Trial name
- NCT07415239
- Testing
- virtual reality intervention, control intervention
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lateral Ligament Repair, Talar Cartilage Lesion
Microfracture Technique for Talar Articular Cartilage Lesions With or Without Lateral Ligament Repairment
To study the clinical efficacy of microfracture combined with lateral ligament repairment for cartilage lesions of talus through the comparison between microfracture with and without lateral ligament repairment.
- Conditions
- Lateral Ligament Repair, Talar Cartilage Lesion, Microfracture
- Trial name
- NCT03064399
- Testing
- without lateral ligament repairment, lateral ligament repairment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Stress Response, Mood State
Post-biotic Intervention for Acute Stress Management
The study aims to evaluate the sub-chronic effects of colonic delivery of a post-biotic on stress response, mood state, sleep, and cognition in healthy young subjects with elevated self-reported stress levels.
- Conditions
- Stress Response, Mood State, Sleep, Cognition
- Trial name
- PIAS (NCT06097182)
- Testing
- Post-biotic (Colonic-Delivery capsule), Post-biotic (Regular Administration capsule)
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Sleep Deprivation, Military Activity
Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?
This study aims to examine the effectiveness of ammonia inhalants in countering the effects of total sleep deprivation on cognitive and physical performance tests relevant to military personnel.
- Conditions
- Sleep Deprivation, Military Activity, Sleep, Cognitive Change
- Trial name
- NCT05868798
- Testing
- Ammonia Inhalant
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jan Malecek
Stress Reaction, Stress Related Disorder
Research on the Effects of Combined Neurostimulation Protocols on Stress
The study examines the effects of the combined use of two different non-invasive brain stimulation (NIBS) techniques targeting the DLPFC on stress reactivity and recovery.
- Conditions
- Stress Reaction, Stress Related Disorder, Major Depressive Disorder
- Trial name
- NCT03722095
- Testing
- active tDCS, iTBS
- Where
- Belgium
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Ghent
Acute Stress Reaction, Cognitive Performance
Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction
The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.
- Trial name
- ASR (NCT06390267)
- Testing
- Sparrow Hawk (Active)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Spark Biomedical, Inc.
Stress, Stress, Psychological
Stress & Resilience Study
Goal 1: The investigators will quantify lifetime stress burden and examine mechanisms linking Adverse Childhood Experiences (ACEs) and health.
- Conditions
- Stress, Stress, Psychological, Stress, Physiological, Stress, Emotional
- Trial name
- CALSTAR (NCT06063174)
- Testing
- Education Program, Think Well Program, Be Well Program
- Where
- United States
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Motivation, Drug Effect
How Stress Alters Opioid Drug Effects
The main objective of the study is to test the hypothesis that opioid drug effects vary as a function of pre-drug affective state.
- Conditions
- Motivation, Drug Effect, Stress Reaction, Misuse, Opioid
- Trial name
- OPIOIDREWARD (NCT06485817)
- Testing
- Oxycodone, Stress State Induction, Control State Induction
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Stress Reaction, Sleep Disturbance
Functional Assessment of Ashwagandaha Root Extract During Weight Loss
Patients who are involved in a clinical protocol driven 12 week medical weight loss intervention will be randomized to receive either a placebo or 600 mg of an ashwagandha root extract.
- Conditions
- Stress Reaction, Sleep Disturbance, Craving, Obesity
- Trial name
- NCT03112824
- Testing
- Ashwagandha Root Extract Capsule
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Appetite and General Nutritional Disorders, Sedentary Lifestyle
Metabolic Response to Playing Video Games: Two Arm Trial
Previous studies have shown that subjects who play video games are prone to consume larger quantities of food than subjects who are simply resting.
- Trial name
- NCT02075827
- Testing
- Competitive video game, Little Big Planet
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College, London
Defect of Articular Cartilage, Osteoarthritis
Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using…
- Conditions
- Defect of Articular Cartilage, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539030
- Testing
- Microfracture, CartiFill
- Where
- 12 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Military Operational Stress Reaction, Malnutrition (Calorie)
Effects of Protein Supplementation on Lean Body Mass Recovery From Extreme Military Training
The purpose of this study is to evaluate the physiological consequences of extreme military training and determine whether protein supplementation enhances recovery by promoting gains in lean body mass.
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT02057094
- Testing
- Protein, High-Protein, and Control
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine