Clinical trials: Stress Testing
Ischemia, Myocardial
Quantitative Stress Echocardiography to Diagnose Myocardial Ischaemia
Patients with chest pain on exertion need a reliable non-invasive test to identify if they have inducible myocardial ischaemia. This would reduce the use of diagnostic coronary arteriography, avoid its risks and costs, and guide…
- Trial name
- DEVISE (NCT03659526)
- Testing
- Deformation imaging
- Where
- 4 sites in Belgium, Sweden and 1 more
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University Hospital of Wales
Pregnancy, Maternal Anxiety
Music Listening During NST Monitoring
This study evaluated whether listening to music during routine non-stress test (NST) monitoring affects fetal parameters and maternal psychological outcomes.
- Conditions
- Pregnancy, Maternal Anxiety, Fetal Well-Being
- Trial name
- NCT07414641
- Testing
- Music Listening During NST
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Diabetes Mellitus
Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
To compare effect of acarbose versus glibenclamide treatment on mean amplitude of glyclemic excursion and oxidative stress in diabetes individuals who failed to control their glucose by metformin therapy alone
- Trial name
- NCT00417729
- Testing
- Acarbose
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Taichung Veterans General Hospital
Hypertrophic Cardiomyopathy
Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
The primary objective of this study was to evaluate the effect of eleclazine (GS-6615) on exercise capacity as measured by Peak oxygen uptake (VO2) achieved during cardiopulmonary exercise testing (CPET), in participants with…
- Trial name
- LIBERTY-HCM (NCT02291237)
- Testing
- Eleclazine
- Where
- 46 sites in United States, Australia and 6 more
- Volunteers
- 172 people
- Sponsor
- Gilead Sciences
Endothenial Dysfunction, Iron Status
Inflamation, Gut Leakage, Iron Status After 6000m Ergometer Test in Elite Rowers.
The influence of a 6000m ergometer test on the markers of gut injury, endotoxemia, iron status, stress and inflammation in elite rowers.
- Conditions
- Endothenial Dysfunction, Iron Status, Oxidative Stress
- Trial name
- 6000m (NCT06890741)
- Testing
- exercise test
- Where
- Poland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Body Composition, Exercise Test
Identification of Sports Talents in Boxers
This study aims to identify sporting talents by profiling a group of young boxers residing in the State of Mexico using unsupervised machine learning methods.
- Conditions
- Body Composition, Exercise Test, Psychological Well-Being
- Trial name
- NCT06269848
- Where
- Mexico
- Volunteers
- 178 people
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
COPD (Chronic Obstructive Pulmonary Disease)
Comparative Efficacy of Once-daily LAMA/LABA Combinations Versus Tiotropium on Constant-work-rate Cycle Endurance in COPD
This study is designed to directly compare the effects of widely available long-acting bronchodilator therapies in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- COMPETE (NCT07541378)
- Testing
- Tiotropium, Olodaterol, Umeclidinium
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Bialystok
Stress, Physiological, Stress, Psychological
A Comparison of Acute Psychobiological Responses to Laboratory Stress Tests
The Mannheim Multicomponent Stress Test (MMST) is a validated laboratory stress test that combines cognitive, emotional, acoustic and motivational stress components.
- Trial name
- NCT06066320
- Testing
- MMST, TSST
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Heart Failure, Vitamin D Deficiency
Vitamin D3 Supplementation for Heart Failure Patients
The purpose of this study is to determine if treatment with vitamin D3 of 10,000 International Units (IU) daily in vitamin D deficient patients for 6 months will improve B type natriuretic peptide (BNP), a marker of heart…
- Conditions
- Heart Failure, Vitamin D Deficiency, Cardiomyopathy, Congestive Heart Failure
- Trial name
- NCT01636570
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Heidi Moretti, MS, RD
Coronary Artery Disease (CAD)
A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT)
The purpose of this study is to demonstrate that the strength of agreement between single photon emission computed tomography (SPECT) imaging with regadenoson following inadequate exercise stress testing and SPECT imaging with…
- Trial name
- EXERRT (NCT01618669)
- Testing
- Regadenoson, Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI)
- Where
- 69 sites in United States, Argentina and 2 more
- Volunteers
- 1,147 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Heart Transplantation
Imminently Effect of Interval Training With High Intensity (HIT) After Heart Transplantation
High intensity Interval training (HIT) has repeatedly been documented to have superior positive effects on oxygen uptake and general physical health compared to continuous moderate exercise in healthy individuals and patients…
- Trial name
- NCT02602834
- Testing
- interval training, moderate exercise
- Where
- Norway
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Single-ventricle, Congenital Heart Disease
Correlation Between 3D Echocardiography and Cardiopulmonary Exercise Testing in Patients With Single Ventricle
Congenital heart disease (CHD) is the leading cause of birth defects, with an incidence of 0.8%. Among CHD, univentricular heart disease or "single ventricle" is rare and complex.
- Trial name
- VU3D (NCT05118152)
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Mucopolysaccharidoses
Assessment of Factors That Affected Respiratory Parameters in Mucopolysaccharidoses Patients
Respiratory system affects in mucopolysaccharidosis (MPS) disease. Respiratory system symptoms are seen in almost every MPS patients and respiratory failure is one of the most common causes of death in this population.
- Trial name
- NCT04491747
- Testing
- functional capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Stem Cell Transplantation
Physical Functions in Allogeneic-HSCT Candidates
Physical inactivity and impairments in physical functions have been observed in patients due to hematological malignancy itself and treatments of chemotherapy, radiotherapy, corticosteroids.
- Trial name
- NCT03915249
- Volunteers
- 49 people
- Sponsor
- Gazi University
Pulmonary Disease, Chronic Obstructive
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
More patients with chronic obstructive pulmonary disease (COPD) die from cardiovascular disease than direct pulmonary complications.
- Trial name
- NCT01398943
- Testing
- Tetrahydrobiopterin (BH4), Antioxidant Cocktail
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Augusta University
Cardiovascular Diseases, Coronary Disease
Coronary Artery Calcium, Exercise Tests, and CHD Outcome
To investigate coronary artery calcium (CAC), detected by electron beam computed tomography (EBCT), as a predictor of coronary heart disease (CHD) mortality and morbidity, stroke, and all-cause mortality in a historical cohort…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Disorders, Heart Diseases
- Trial name
- NCT00005562
- Sponsor
- The Cooper Institute
Physiological Stress
Exercise and Stress Management Post Autologous and Allogeneic Transplant (BMT CTN 0902)
This is a Phase III, randomized, unblinded, multicenter, prospective comparative study. The purpose of this study is to test whether exercise or stress management training delivered to autologous and allogeneic hematopoietic cell…
- Trial name
- NCT01278927
- Testing
- Exercise, Stress Management, Exercise and Stress Management
- Where
- 19 sites in United States
- Volunteers
- 711 people
- Sponsor
- Medical College of Wisconsin
Posttraumatic Stress Disorder
Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial
This study will consist of a single session of MDMA-assisted therapy with a full dose of MDMA for people who took part in a study of MDMA-assisted therapy in people with posttraumatic stress disorder (PTSD) whose PTSD symptoms…
- Trial name
- NCT01458327
- Testing
- Midomafetamine, Therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Resilient Pharmaceuticals
Chest Pain, Coronary Artery Disease
Study of Value of Cardiac PET Scans With or Without CT Angiography and/or Measurement of Coronary Flow Reserve
How does PET myocardial perfusion imaging involving CT angiography and measurement of coronary flow reserve affect patient care.
- Trial name
- NCT00669968
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Kettering Health Network
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Breathlessness Perceptions Within Respiratory Diseases
Breathlessness is a complex symptom that results in poor quality of life, increased hospitalisations and increased mortality. Breathlessness is influenced by physiological, psychological and functional factors but these are…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Interstitial Lung Disease (ILD), Bronchiectasis
- Trial name
- BiRD (NCT07648082)
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester