Clinical trials: Stricture
Aortic Stenosis, Iron-deficiency
Iron Supplementation in TAVI and SAVR Patients With Iron Deficiency
The INERTIA trial is a multicenter double-blinded randomized trial of intravenous iron supplementation in patients with severe aortic stenosis and iron deficiency undergoing TAVI or SAVR.
- Trial name
- INERTIA (NCT04786769)
- Testing
- Ferric carboxymaltose
- Volunteers
- 2,500 people
- Sponsor
- Hospital de Santa Cruz, Portugal
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection
Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Scoliosis Lumbar Region, Lumbar Spondylolisthesis
- Trial name
- NCT04341831
- Testing
- Teicoplanin
- Volunteers
- 120 people
- Sponsor
- Bezmialem Vakif University
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial
Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN)
This is a monocentric randomized prospective trial comparing 2 different endovascular strategies of intracranial arterial angioplasty in case of refractory intracranial arterial vasospastic stenosis : chemical angioplasty…
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Intracranial, Stenosis, Ruptured Cerebral Aneurysm
- Trial name
- SAVEBRAIN (NCT05268445)
- Testing
- Chemical and Mechanical Angioplasty for Refractory Intracranial Arterial Vasospastic Stenosis
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Erasme University Hospital
Coronary Artery Disease, Aortic Valve Stenosis
MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
MiECS is one of the largest multicentre randomised controlled trials on extracorporeal circulation conducted under the auspices of Minimal Invasive Extracorporeal Technologies International Society (MiECTiS).
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Extracorporeal Circulation; Complications
- Trial name
- MiECS (NCT05487612)
- Testing
- Minimal Invasive Extracorporeal Circulation, Conventional cardiopulmonary bypass
- Where
- 13 sites in Canada, Germany and 4 more
- Volunteers
- 1,300 people
- Sponsor
- Aristotle University Of Thessaloniki
Left Bundle-Branch Block, Aortic Valve Stenosis
Clinical Monitoring Strategy Versus Electrophysiology-guided Algorithmic Approach With a New LBBB After TAVI
The primary hypothesis of the proposed study is that an electrophysiology-based algorithmic approach is superior to standard clinical follow-up with 30-day monitoring in reducing the combined endpoint of syncope, hospitalization…
- Trial name
- COME-TAVI (NCT03303612)
- Testing
- Pacemaker implant, Transcutaneous cardiac monitor
- Where
- 10 sites in Canada, France
- Volunteers
- 250 people
- Sponsor
- Montreal Heart Institute
Coronary Stenosis
POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI)
The primary objective of this study is to study the safety and efficacy of the BiOSS LIM C with respect to Patient oriented Composite Endpoint (PoCE) at 12 months in a "real world" left-main bifurcation population and as compared…
- Trial name
- POLBOS-LM (NCT03508219)
- Testing
- BiOSS LIM C
- Where
- 15 sites in France, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- ECRI bv
Aortic Stenosis, Heart Block
Conduction Disease After Transcatheter Aortic Valve Replacement
This is a prospective single center Cardiology department observational study. The study aim is to better understand the predictors of high grade conduction abnormalities associated with TAVR such that a more robust…
- Conditions
- Aortic Stenosis, Heart Block, Aortic Insufficiency
- Trial name
- NCT04489095
- Testing
- Electrophysiology Study
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Henry Ford Health System
Coronary Angioplasty and Stenting, Single de Novo Coronary Artery Stenoses
IVUS Controlled Stenting
Stent placement is now widely accepted to improve the results of angioplasty (an operation to widen the blood vessel) and decreasing the need for further surgery.
- Trial name
- NCT02128412
- Testing
- Oversized stent deployed at low pressure (Multi-Link Bare Metal Stent or Xience Prime Evenolimus Eluting Stent), Stent deployed at high pressure (Multi-Link Bare Metal Stent or Xience Prime Evenolimus Eluting Stent)
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Sydney South West Area Health Service
Oesophageal Cancer
Esophageal Self-expandable Metal Stent for Malignant Strictures: a Safety and Efficacy Study
A single center prospective observational non-randomized clinical study to assess the safety and efficacy of placement of a new esophageal self-expandable metal stent (SEMS) for palliation of patients with malignant dysphagia.
- Trial name
- ENTRANCE (NCT06364553)
- Testing
- Esophageal self-expandable metal stent
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Erasmus Medical Center
Aortic Valve Disease, Aortic Valve Stenosis
Evaluating the Safety and Efficacy of Prosthetic Polymer Heart Valves for the Treatment of Aortic Valve Disease
The purpose of this study is to conduct the initial clinical investigation of the HeartHill Medical's polymer aortic valve, namely PoliaVavle，to collect evidence on the device's safety and performance.
- Conditions
- Aortic Valve Disease, Aortic Valve Stenosis, Aortic Valve Regurgitation
- Trial name
- NCT06518681
- Testing
- PoliaValve (Aortic)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Suzhou Hearthill Medical Technology Co.,LTD
Aortic Valve Stenosis
Cardiovascular Rehabilitation in Patients With Severe Aortic Stenosis Submitted to Valvar Correction
This study will be evaluate the autonomic, endothelial and hemodynamic functions, inspiratory muscle strength, peripheral tissue oxygenation, peripheral and respiratory muscle architecture, and inflammatory profile of severe AS…
- Trial name
- CARE-AS-MOTION (NCT02468219)
- Testing
- cardiovascular rehabilitation program
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Urethral Stricture
A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty
The investigators propose a randomized non-blinded comparison of dorsal vs. ventral approach for buccal mucosa graft urethroplasty in the bulbar urethra. Buccal mucosa graft is a common method of repairing the strictured urethra.
- Trial name
- DvV (NCT02634619)
- Testing
- Ventral buccal mucosa onlay urethroplasty, Dorsal buccal mucosa onlay urethroplasty
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of California, San Francisco
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
The MOTION Study - Treatment of LSS With the MILD Procedure
Prospective, multicenter, randomized controlled clinical study examining functional improvement in lumbar spinal stenosis (LSS) patients with neurogenic claudication who are treated with the MILD procedure plus conventional…
- Trial name
- NCT03610737
- Testing
- MILD Procedure, Conventional Medical Management (CMM)
- Where
- 18 sites in United States
- Volunteers
- 155 people
- Sponsor
- Vertos Medical, Inc.
Carotid Stenosis
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS).
- Trial name
- RICSICAS (NCT07412249)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Shenyang Military Region
Coronary Artery Stenosis
Kidney Damage In Patients With Severe Fall In eGFR
This is a pilot study using a randomized, double blinded, comparison of two iodinated contrast agents used during percutaneous coronary intervention (PCI).
- Trial name
- NCT01136915
- Testing
- Iopamidol 370, Iodixanol 320
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Bracco Diagnostics, Inc
Radiculopathy, Cervical Region
Predictors of Treatment Response to Stellate Ganglion Block in Cervical Radicular Pain
Purpose: Stellate ganglion block (SGB) is a procedure that uses ultrasound to guide a needle near a group of nerves in the neck called the stellate ganglion. A local anesthetic is then injected to block pain signals.
- Trial name
- NCT07476235
- Testing
- Cervical multifidus fatty degeneration, Primary etiology of foraminal stenosis, Steroid use during stellate ganglion block
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Asan Medical Center
Hypertrophic Cardiomyopathy
A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada
This real-world study will describe the demographic and clinical characteristics and mavacamten treatment of adult patients with obstructive hypertrophic cardiomyopathy who participated in the Bristol-Myers Squibb (BMS)-sponsored…
- Trial name
- NCT06549608
- Testing
- Mavacamten
- Where
- Canada
- Volunteers
- 683 people
- Sponsor
- Bristol-Myers Squibb
Carotid Stenosis
Clopidogrel Resistance and Embolism in Carotid Artery Stenting
The purpose of this study is to evaluate the efficacy and safety of the ticlopidine + ginko biloba compared to clopidogrel in clopidogrel resistant patients undergoing carotid artery stent placement.
- Trial name
- CRECAS (NCT02133989)
- Testing
- Ticlopidine + Ginko biloba, Clopidogrel
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Aortic Valve Stenosis
Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis
Background: Aortic valve stenosis is a disease that makes a major heart valve get smaller. This reduces heart function and causes death.
- Trial name
- NCT01905852
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Aortic Valve Stenosis, Heart Valve Diseases
Antagonization of Heparin With Protamine Sulfate After TAVI
Transcatheter aortic valve replacement (TAVR) is now the first therapeutic option offered to high and intermediate risk patients with symptomatic aortic stenosis but even to low-risk, when the aortic valve is tricuspid and the…
- Trial name
- ATLANTIS-Prota (NCT06215378)
- Testing
- Antagonization of heparin with protamine sulfate
- Where
- France
- Volunteers
- 940 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.