Clinical trials: Stricture Urethra
Urethral Meatal Stenosis
The Improvement in Uroflow and Postvoid Residual Urine After Urethral Meatotomy in Children With Meatal Stenosis
The improvement in uroflow and postvoid residual urine in children after urethral meatotomy for meatal stenosis. The hypothesis is that there is an improvement in both parameters, thus justifying the procedure.
- Trial name
- NCT01214525
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Meir Medical Center
Urethra Stenosis
DoVe Trial: Dorsal Onlay Versus Ventral Onlay in Isolated Bulbar Urethral Strictures
For bulbar urethral strictures, it remains unclear whether ventral onlay graft urethroplasty is non-inferior to dorsal onlay graft urethroplasty in terms of patency rates.
- Trial name
- DoVe (NCT04551417)
- Testing
- Free graft urethroplasty
- Where
- Belgium
- Volunteers
- 240 people
- Sponsor
- University Hospital, Ghent
Urethral Stricture
The Accuracy of Pulsed Fluoroscopy Retrograde Urethrogram Vs the Traditional Retrograde Urethrogram In Diagnosing Urethral Stricture
This study is designed as a prospective comparative randomized clinical study to determine the diagnostic accuracy (sensitivity, specificity, positive predictive value, and negative predictive value) of pulsed fluoroscopy…
- Trial name
- NCT05519566
- Testing
- Retrograde Urethrogram
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Northern Ontario School of Medicine
Urethral Stricture
Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers
This study investigates safety and efficacy of surgical treatment of patients with anterior urethral stricture using a tissue-engineered construct based on autologous buccal mucosa cells and matrix from reconstituted collagen and…
- Trial name
- NCT03205670
- Testing
- Urethroplasty with a tissue-engineered construct
- Where
- Russia
- Volunteers
- 6 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Urethral Stricture
Bioengineered Collagen Implant for Urethral Stricture Repair
The field of research for this study is tissue engineering and the utilization of a bioengineered collagen implant as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of distal urethral…
- Trial name
- NCT05463991
- Testing
- Bioengineered collagen implant
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- Regenosca SA
Urethral Stricture, Surgery
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of transecting anastomotic repair.
- Conditions
- Urethral Stricture, Surgery, Urologic Diseases
- Trial name
- VeSpAR (NCT03572348)
- Testing
- Transecting anastomotic repair (tAR), Vessel-sparing anastomotic repair (vsAR)
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Urethral Stricture
Role of Uttarbasti in the Management of Mutra Marga Sankoch (Urethral Stricture)
Uttarbasti is per urethral administration of medicated oil which has been recommended by Sushrut for urinary track disorders. As far as conventional surgery is concerned urethral stricture still remains a challenge due to post…
- Trial name
- NCT00535717
- Testing
- uttarbasti (per urethral administration of medicated oil )
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maharashtra University of Health Sciences
Anterior Urethral Stricture, Male
Optilume Registry for Treatment of Stricture of the Anterior Urethra
The purpose of this registry is verifying the continued safety and effectiveness of the Optilume DCB clinical use in patients undergoing dilation of the urethral stricture.
- Trial name
- NCT05479422
- Where
- 13 sites in Belgium, Italy and 3 more
- Volunteers
- 150 people
- Sponsor
- European Association of Urology Research Foundation
Urethral Stricture
Platelet Rich Plasma Versus Mitomycin C Injection Following Visual Internal Urethrotomy in Urethral Stricture
this is a randomized clinical trial that was conducted at Ain Shams University to compare the effectiveness and safety of two different substances injected after visual internal urethrotomy for treating urethral stricture in…
- Trial name
- NCT07883837
- Testing
- Visual internal urethrotomy followed by submucosal intralesional mitomycin C injection, Visual internal urethrotomy followed by submucosal Platlet Rich Plasma injection
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Urethral Stricture
Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture
the purpose is to evaluate the outcome of visual internal uretherotomy with Holmium laser along with intralesional steroid injection.
- Trial name
- NCT05078788
- Testing
- Laser uretherotomy, Laser uretherotomy with triamcinolone
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Ain Shams University
Urethral Stricture, Male
Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
The field of research for this study is tissue engineering and the utilization of a small intestinal submucosa graft as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of anterior urethral…
- Trial name
- NCT06192654
- Testing
- Small intestinal submucosa (SIS) graft urethroplasty, Autologous oral bucal mucosa graft urethroplasty
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xiaoyong Zeng
Urethral Stricture
Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral Stricture
The goal of this randomized controlled trial is to To assess the effectiveness of intermittent bladder catheterization (IBC) in reducing the recurrence of urethral stricture among females in tertiary care hospital, Lahore.
- Trial name
- NCT06064968
- Testing
- Intermittent bladder catheterization
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Kidney Transplant; Complications, Kidney Transplant Infection
Early vs Late Urinary Catheter Removal After Renal Transplantation
The purpose of this study is to compare frequency of UTI, urine leak and need for reoperation in patients after renal transplant with early or delayed Foley catheter removal.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Urinary Fistula, Urinary Tract Infections
- Trial name
- ELUCATR (NCT04815954)
- Testing
- Urinary catheter removal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Hypospadias Repair
Hemostasis During Hypospadias Surgery
A comparison between the two hemostatic methods of hypospadias repairing operation, in terms of early and mid-term (up to 6 months) failure rate (wound dehiscence and urethral stricture needing reoperation) between the two…
- Trial name
- NCT02268019
- Testing
- tourniquet application, epinephrine injection
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Recurrence
Role of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy
It was a randomized controlled trial conducted at department of Urology, Armed Forces Institute of Urology, Rawalpindi from 1st January, 2018 July 2019 to 31st March 2021 to determine the role of oral steroids after Direct Vision…
- Trial name
- NCT05069883
- Testing
- Steroid Drug, No steroid
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Services Hospital, Lahore
Urethral Stricture
Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture
To evaluate the effectiveness of administering mitomycin C through intralesional injection after performing visual internal urethrotomy (VIU) for the treatment of recurring urethral stricture.
- Trial name
- NCT06232005
- Testing
- Mitomycin c
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Stricture Urethra
The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence
The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence
- Trial name
- prp vs VIU (NCT07837167)
- Testing
- PRP injection, VIU
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Urethra Stricture
LishitonglinUS-01 Trial
This study intends to conduct a prospective, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of Lishi Tonglin Granule (a hospital-formulated innovative prescription) developed in our…
- Trial name
- NCT07769060
- Testing
- Lishitonglin Formula granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University First Hospital
Urethral Stricture
Urethral Stricture Database
Establishment of a clinical urethral stricture database for a prospective longitudinal cohort study.
- Trial name
- NCT06362083
- Testing
- Questionnaires and data collection
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University of Graz