Clinical trials: Stroke, Chronic
Hemiplegia, Spastic
THE EFFECTS OF SUBTALAR JOINT MOBILIZATION ON PATIENTS WITH CHRONIC STROKE
Adequate ankle motion for normal gait ranges from 10° to 15° of dorsiflexion passive range of motion (DF-PROM) to allow the tibia to move over the talus.
- Trial name
- NCT03788629
- Testing
- Talocrural joint MWM mobilization, Subtalar joint MWM mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Stroke Patients
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest
The goal of this clinical trial is to study the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on resting-state brain functional connectivity.
- Trial name
- COVAGNIRS (NCT07282106)
- Testing
- Active taVNS arm
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Stroke, Spasticity
Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors
Stroke is one of the leading causes of long-term disability worldwide. Many patients who survive a stroke experience muscle stiffness (called spasticity), especially in the ankle and foot muscles, which makes walking difficult…
- Conditions
- Stroke, Spasticity, Plantar Flexors
- Trial name
- LLLT-STROKE (NCT07273591)
- Testing
- Low Level Laser Therapy, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montiha Azeem
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Stroke, Healthy Adult
Effects of a Robot-based Sensorimotor Upper Limb Rehabilitation Paradigm in Chronic Stroke
Sensorimotor function of the upper limb is commonly impaired after stroke, even in the chronic phase (>6 months post-stroke). Nevertheless, good sensorimotor function is needed for daily life functioning.
- Trial name
- RCT ROBUST (NCT07547800)
- Testing
- ROBUST, Kinarm therapy
- Where
- Belgium
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
Perturbed-balance Training During Treadmill Walking for Stroke Subjects
A control and a post-stroke subject with right-side chronic hemiparesis were studied. The post-stroke subject underwent 30 sessions of balance-perturbed training while walking on an instrumented treadmill where the Balance…
- Trial name
- BALANCESI (NCT03285919)
- Testing
- Balance Assessment Robot (BAR™)
- Where
- Slovenia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Upper Extremity Paresis
PNF Strengthening and De-lorme and Watkins Exercises on Upper Extremity Function and Strength in Stroke Patients
The aim of this study is to evaluate the effects of proprioceptive neuromuscular facilitation strengthening exercises and de-Lorme and Watkins exercises program in stroke patients with upper limb weakness in chronic stroke…
- Trial name
- NCT05904795
- Testing
- PNF strengthening exercises, de-lorme and watkins exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cognitive Dysfunction, Stroke
Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project
The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling…
- Conditions
- Cognitive Dysfunction, Stroke, Dementia, Depression
- Trial name
- VESPAR (NCT05649800)
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Stroke Rehabilitation
Vibratory Perturbation-based Pinch Task Training for Stroke Patients
The investigator assumed that perturbed-event-induced vibrotactile cueing enable more precision arm movement adjustment, sensory function and dexterity improvement in the spastic arm.
- Trial name
- NCT03798340
- Testing
- Vibratory perturbed task-specific movement training, Traditional task-oriented facilitation, Sensorimotor training
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Stroke, Muscle Hypertonia
Antagonist Activation Measurement at the Ankle Using High-density and Bipolar Surface EMG in Chronic Hemiparesis
In chronic hemiparesis, abnormal antagonist muscle activation in the paretic lower limb contributes to impair ambulation capacities.
- Conditions
- Stroke, Muscle Hypertonia, Spasticity, Muscle
- Trial name
- CC2017 (NCT06099132)
- Testing
- Electromyographic measurements
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Stroke, Acute Stroke
The Effects of Gait Rehabilitation After Stroke by Treadmill-based Robotics Versus Traditional Gait Training
This multicenter non-randomized controlled trial aims to investigate the effectiveness (an increase of the walking speed in the 10 Meter Walk Test - 10MWT) of the robotic treatment with exoskeleton or end-effector system compared…
- Conditions
- Stroke, Acute Stroke, Chronic Stroke
- Trial name
- TREAD_STROKE (NCT03688165)
- Testing
- Treadmill-based Robotic Gait Training, Traditional Over-ground Gait Training
- Where
- 4 sites in Italy
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Chronic Stroke, Non-use of the Paretic Upper Limb
Actimetry Monitoring of the Paretic Upper Limb in Chronic Post Stroke.
After a stroke, 80% of patients continue to have difficulty using their paretic upper limb in activities of daily living (ADL) despite post-stroke rehabilitation practices that aim to promote the use of the paretic upper limb.
- Trial name
- ParUse (NCT05581602)
- Testing
- Wearing bracelets (3-Axis Logging Accelerometer)
- Where
- 2 sites in France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cerebral Palsy, Stroke
A Longitudinal Study of Motor Control and Brain Images in Patients With Brain Damage
The primary goal of this study is to establish and evaluate an image-based biomarker for the impaired motor control and sensory information processing present in Cerebral palsy (CP) and stroke patients.
- Trial name
- NCT01883960
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Augmentation of Locomotor Adaptation Post-Stroke
This project will evaluate two different methods of normalizing the center of mass acceleration (COMa) in individuals post-stroke, specifically focusing on rates and pattern of recovery to analyze walking-specific adaptations as…
- Trial name
- NCT02892084
- Testing
- tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Stroke, Healthy
Effects of Vibration on Motor Function of Survivors of Chronic Stroke
The aim of this study is to evaluate how vibration of the tendons enhances arm and hand training in survivors of chronic stroke.
- Trial name
- NCT06663501
- Testing
- Assisted Motion with Enhanced Sensation training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab