Clinical trials: Stroke, Chronic
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Chronic Stroke
Rimonabant for Improving Walking Ability in Patients With Chronic Stroke
The mail goal of this clinical trial is assess the effect of rimonabant in walking ability in people who experienced a stroke at least 12 months before enrollment.
- Trial name
- RIMOSTROKE-1 (NCT07913763)
- Testing
- Rimonabant
- Where
- 6 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Sinfatin S.L
Polyvascular Disease, Atherosclerosis
Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis
Аn international, multicenter, non-interventional real-life clinical practice Register studying the Actual therapeutic patient population with Multifocal Atherosclerosis in the Russian Federation and Eurasian countries
- Conditions
- Polyvascular Disease, Atherosclerosis, Atherosclerosis Generalized, Cardiovascular Diseases
- Trial name
- KAMMA (NCT05189847)
- Where
- Russia
- Volunteers
- 3,059 people
- Sponsor
- Eurasian Association of Therapists
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Stroke
Primed vs. Unprimed rTMS in Chronic Stroke
The goal of stroke rehabilitation is to restore function to the weak side of the body. However, this is often a difficult task to accomplish due to not only to damage from the stroke, but from increased excitability in the…
- Trial name
- NCT01757821
- Testing
- real 6-Hz primed low-frequency rTMS, real 1-Hz rTMS only
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Ischemic Stroke
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)
Evaluation of the safety and tolerability of escalating doses of NR1 administered intracerebrally at a single time-point post-injury to subjects with chronic ISS with or without cortical stroke.
- Trial name
- NCT04631406
- Testing
- Neural Stem Cells
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Clarion Cells, Inc.
Chronic Stroke
Motor Imagery Training for Upper Limb Functional Strength in Chronic Stroke Patients
Stroke is a leading cause of upper extremity deficits worldwide. Persistent upper extremity dysfunction affects many post stroke patients and is strongly associated with decreased activities of daily living and poor quality of…
- Trial name
- NCT06945185
- Testing
- Intervention Group A Conventional Physical Therapy, Intervention Group B Motor Imagery with Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Foundation University Islamabad
Stroke, Postural Balance
Interactive Posturographic Balance Training Added to Conventional Rehabilitation in Chronic Stroke
Stroke frequently leads to long-term balance impairments, increased fall risk, and reduced independence in daily activities. In chronic stroke patients, deficits in sensory integration and postural control may persist despite…
- Trial name
- NCT07448948
- Testing
- Biofeedback-Based Interactive Posturographic Balance Training, Conventional Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke, Pain
Post-stroke Pain taVNS
The purpose of this study is to explore whether a non-invasive form of ear stimulation called transcutaneous auricular vagus nerve stimulation (taVNS) can change the way participants perceive pain.
- Trial name
- NCT06456385
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Stroke, Cerebrovascular Accident
Enhancing Plasticity in Stroke Patients With Severe Motor Deficit
This study will evaluate the effectiveness of sustained peripheral nerve stimulation coupled with functional motor training, to improve hand motor function in poorly recovered stroke patients.
- Trial name
- NCT02633215
- Testing
- S88 Dual Output Stimulator by Grass Technologies
- Volunteers
- 36 people
- Sponsor
- Lumy Sawaki
Stroke
Low Level LASER Therapy in Chronic Stroke Patients With Spastic Planter Flexors.
Low-intensity LASER therapy on the spastic muscle, would result in improving muscle performance and improving the functional capacity of individuals under the exercises imposed by physical therapy.
- Trial name
- NCT05425225
- Testing
- Low level LASER therapy, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Stroke
Comparison of Graded Motor Imagery and Mirror Therapy in Chronic Stroke Rehabilitation
The study is conducted to assess whether the GMI or MT reduce the level of spasticity. Also to compare the level of independence in GMI and MT in the chronic stroke patients.
- Trial name
- NCT06980181
- Testing
- Graded Motor Imagery, Mirror Therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Stroke, Cerebral Palsy
Multimodal Tracking of Therapy Activity and Effort During Rehabilitation
This study looks at whether everyday rehabilitation therapy sessions can be recorded and measured in a more complete, objective way.
- Conditions
- Stroke, Cerebral Palsy, Spinal Cord Injury, Parkinsons
- Trial name
- NCT07739134
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- ETH Zurich
Stroke, Dual Task
Rhythmic Auditory Stimulation and Dual-task Gait Training in Chronic Stroke
Rhythmic auditory stimulation and dual-task gait training may improve post-stroke mobility, but evidence regarding integrated programmes and age-related differences in treatment response remains limited.
- Conditions
- Stroke, Dual Task, Gait Training, Auditory Task
- Trial name
- NCT07709130
- Testing
- Rhythmic Auditory Stimulation and Motor Dual-Task Gait Training Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Recep Tayyip Erdogan University
Stroke
Replacing Canes With an Elasticated Orthosis in Chronic Stroke Patients: The Influence on Gait and Balance. A Series of N-of-1 Trials
This study aims to investigate the effect of an elasticated orthotic garment "Thera Togs" on walking ability and balance in currently cane using chronic stroke subjects (minimum 6 months post stroke) using a series of N-of-1…
- Trial name
- NCT03642444
- Testing
- Cane, Elasticated worn orthotic-garment
- Volunteers
- 4 people
- Sponsor
- Technical University of Bern
Stroke, Spastic Hemiplegia
BTX-A and Mirror Therapy for Chronic Stroke Spasticity
Stroke is one of the leading causes of disability worldwide, particularly affecting the upper extremities and thus negatively impacting patients' activities of daily living and quality of life.
- Trial name
- NCT07331844
- Testing
- Botulinum toxin type A (Botox®, Allergan), Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Chronic Stroke
Neuroimaging Biomarkers Toward a Personalized Upper Limb Action Observation Treatment in Chronic Stroke Patients
Much recent interest was raised by the use of Action Observation Treatment (AOT) in stroke patients rehabilitation. AOT, well-grounded in neurophysiology, is an updated approach, based on mirror neuron system (MNS) used to…
- Trial name
- BE-TOP (NCT04047134)
- Testing
- Action Observation Treatrment, Observation of videos with Non Motor contents
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS San Raffaele
Renal Replacement Therapy, Renal Dialysis
A Clinical Trial of IntensiVE Dialysis
This study will assess clinical outcomes of extended weekly hours of haemodialysis (>= 24 hours per week) compared with standard hours of haemodialysis (<=18 hours/week) in people with ESKD.
- Conditions
- Renal Replacement Therapy, Renal Dialysis, End Stage Kidney Disease, End Stage Renal Disease
- Trial name
- ACTIVE (NCT00649298)
- Testing
- haemodialysis
- Where
- 40 sites in Australia, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- The George Institute
Balance, Gait Analysis
Effectiveness of Dance Therapy in Stroke Patients.
Hemiparesis following a stroke is associated with persistent deficits in postural control, balance, and social participation, especially in the chronic phase.
- Conditions
- Balance, Gait Analysis, Thermography, Range of Motion, Articular
- Trial name
- NCT07578493
- Testing
- Dance therapy, Regular physiotherapy
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- University of Salamanca
Stroke, Hemiparesis
Neuromuscular and Biomechanical Control of Lower Limb Loading in Individuals With Chronic Stroke
Stroke is the leading cause of long-term disability in the U.S. Individuals with hemiparesis due to stroke often have difficulty bearing weight on their legs and transferring weight from one leg to the other.
- Trial name
- NCT03694028
- Testing
- Limb Loading, Conventional Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Maryland, Baltimore
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