Clinical trials: Stroke, Chronic
Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function.
- Trial name
- NCT06383390
- Testing
- Retatrutide
- Where
- 742 sites in United States, Argentina and 25 more
- Volunteers
- 10,000 people
- Sponsor
- Eli Lilly and Company
Stroke
Motor Excitability Study of High Definition Transcranial Direct Current Stimulation (HD-tDCS) in Chronic Stroke
High definition tDCS will be conducted to both stroke and healthy subjects on primary motor cortex area to explore the motor excitability changes before and after stimulation.
- Trial name
- NCT02960009
- Testing
- HD-tDCS
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke
MyStroke in Chronic Stroke
This is a single-center randomized control trial assessing the impact of a personalized video-based educational platform on patients satisfaction and stroke knowledge in the context of chronic stroke.
- Trial name
- NCT06057753
- Testing
- MyStroke
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Complex Regional Pain Syndromes
Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke
The aim of our study is to investigate transcranial magnetic stimulation (TMS) as a treatment option in Complex Regional Pain Syndrome, disseminate it to a broader patient population, and simultaneously demonstrate its…
- Trial name
- NCT06215079
- Testing
- The Magstim Rapid2 Plus Magnetic Stimulator (Magstim, Whitland, Dyfed, UK), conventional rehabilitation program
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Stroke
An Open-labeled Phase II Study to Evaluate the Efficacy and Safety of GXNPC-1 in Patients with Chronic Stroke
The primary objective of this study is to evaluate the efficacy for subjects with chronic stroke after GXNPC-1 injection.
- Trial name
- NCT04088149
- Testing
- GXNPC1
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Gwo Xi Stem Cell Applied Technology Co., Ltd.
Comorbidities and Coexisting Conditions, Alzheimer Disease
An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia
The CAREPATH will conduct Technical Validation and Usability (TVU) study by involving ≥ 45 target end users (16 patients with MCI or mild dementia with their informal caregivers and 16 healthcare professionals from various…
- Conditions
- Comorbidities and Coexisting Conditions, Alzheimer Disease, Dementia, Malnutrition
- Trial name
- CAREPATH (NCT05104593)
- Testing
- Intervention tested (CAREPATH)
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
Stroke
Transcranial Direct Current Stimulation for Post-Stroke Aphasia
This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and…
- Trial name
- NCT02461355
- Testing
- Aphasia therapy, Anodal tDCS
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Ischemic Stroke
The Effects of tDCS Combined With Balance Training on Lower Limbs Spasticity in Chronic Stroke Patients
Spasticity is one of the most common disorders in patients with central nervous system diseases such as stroke. Transcranial direct current stimulation stimulation (tDCS) is a noninvasive tool that can be used to modulate…
- Trial name
- NCT02610387
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Stroke, Difficulty Walking
Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke
The purpose of this study is to compare two different walking training programs for persons with chronic stroke.
- Trial name
- NCT01180738
- Testing
- Body weight supported treadmill training, Overground walking training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephanie Miller
Cerebral Palsy
FES in Young Children With Perinatal Stroke
Every year about 1 out of every 1,600-5,000 infants has a stroke around the time of birth. Many of these children will have lifelong physical problems. For example, the arm muscles are often paralyzed.
- Trial name
- NCT02975180
- Testing
- FES, Conventional
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University Health Network, Toronto
Heart Failure, COPD
CREATION Health Readmission Risk Assessment Tool
This study occurs in two phases. Phase 1 involves initial item development and measurement validation of a new tool for identifying hospitalized patients at high risk for preventable readmission.
- Conditions
- Heart Failure, COPD, Myocardial Infarction, Coronary Artery Bypass Graft
- Trial name
- NCT03424382
- Where
- United States
- Volunteers
- 1,218 people
- Sponsor
- AdventHealth
Hypertension, Diabetes
Arts & Health Education to Improve Health, Resilience, and Well-Being
This is an 8-week randomized controlled trial to help address health, resilience, and well-being. Participants are randomized into either a health education group or an arts-based health education group.
- Conditions
- Hypertension, Diabetes, Obesity, COPD
- Trial name
- NCT04154579
- Testing
- HeRe We Arts, HeRe We Ed
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lisa Gallagher
Stroke
Eccentric Contraction-based Resistance Exercise for Chronic Stroke Patients
The purpose of this study is to develop an evidence-based rehabilitation treatment method suitable for recovery and improvement of physical function in chronic stroke patients using an eccentric overload flywheel device.
- Trial name
- NCT04600050
- Testing
- usual care and exercise education, Eccentric exercise
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Cerebrovascular Accident
Bilateral Movement Training for People With Stroke
The investigators hypothesized that bilateral handgrip force training would result in significant improvements in paretic hand, arm movements and daily functional performances.
- Conditions
- Stroke, Cerebrovascular Accident, Cardiovascular Disease, Brain Injury
- Trial name
- NCT02247674
- Testing
- Bilateral movement training
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Chueh-Ho Lin
Stroke, Upper Extremity Paresis
Improving Arm and Hand Functions in Chronic Stroke (CIHR 2012-2015)
Improving arm and hand function after stroke has been difficult to achieve within the rehabilitation service provided in the acute stage often due to the limited resource in health care.
- Trial name
- NCT01721668
- Testing
- Music Supported Rehabilitation, Conventional Upper Extremity Therapy
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Baycrest
Chronic Gastritis, Gastric Cancer (GC)
Validating a Medical AI Fine-Tuning Platform for Major Diseases
The goal of this observational study is to leverage the abundant patient resources and standardized medical records from Beijing Friendship Hospital, Xuanwu Hospital, and Beijing Anzhen Hospital, combined with the existing data…
- Conditions
- Chronic Gastritis, Gastric Cancer (GC), Coronary Artery Disease, Stroke
- Trial name
- NCT07795645
- Testing
- Smart Medical Big Data Dataset Construction, Large-Scale Medical Knowledge Graph Construction, Multi-Disease Medical Large Model Fine-Tuning Platform Construction and Fine-Tuning
- Where
- China
- Volunteers
- 96,000 people
- Sponsor
- Beijing Friendship Hospital
CVA (Cerebrovascular Accident)
Implicit Versus Explicit Motor Training for Upper Extremity Rehabilitation in Chronic Stroke Patients
Training methods that improve proprioception of the shoulder joint involve specific tasks targeting joint position sense, kinesthesia, or sense of force. These exercises can involve explicit or implicit motor learning.
- Trial name
- NCT05847595
- Testing
- Implicit motor training program, Explicit motor training program, Selected physical therapy program
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ahmed Anwar
Stroke, Hemiparesis
Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study
The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures.
- Conditions
- Stroke, Hemiparesis, Home-based
- Trial name
- NCT06223529
- Testing
- Therapeutic Instrumental Music Performance
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Anglia Ruskin University
Biomarker, Lipid
Shotgun Mass Spectrometry-based Lipid Profiling in Chronic Inflammatory Diseases
Collect blood from patients admitted for coronary angiography to tubes with heparin, centrifuge and collect plasma. This will be frozen at -80C.
- Conditions
- Biomarker, Lipid, Inflammation, Cardiovascular Diseases
- Trial name
- NCT04786431
- Testing
- Blood collection for lipid profiling by LC-MS
- Volunteers
- 427 people
- Sponsor
- Universidade Nova de Lisboa
Unilateral Cerebral Palsy
Validation of AI for Personalized Assessment and Rehabilitation of Upper Limb in Children With Unilateral Cerebral Palsy
Unilateral Cerebral palsy (UCP) is the most common neurological chronic disease in childhood with a significant burden on children, their families and health care system.
- Trial name
- AInCP (NCT06073522)
- Testing
- Artificial Intelligence for combining multi-domain data acquisition
- Where
- 2 sites in Italy, Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
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