Clinical trials: Stroke, Chronic
Stroke, Upper Limb Rehabilitation
Neurofeedback-Guided BCI Motor Imagery for Upper-Limb Recovery in Chronic Stroke
Stroke can lead to long-term impairment of upper-limb function, particularly in the chronic phase, where recovery is often limited.
- Trial name
- NCT07525609
- Testing
- Motor imagery-based training - Real Neurofeedback
- Volunteers
- 7 people
- Sponsor
- CESPU-Escola Superior de Tecnologias da Saúde de Tâmega e Sousa
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
Stroke
Effect of the Dose of Training in Upper Limb Motor Recovery After Stroke.
The aim of the study is to analyse the effect of intensive training on upper limb function in stroke patients. 20 stroke patients were randomly divided into two groups: the intensive group and the control group.
- Trial name
- NCT06571292
- Testing
- Intensive training with robotic exoskeleton for upper limbs, Task specific training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Stroke
Dextroamphetamine and tDCS to Improve the Fluency
The proposed study aims to evaluate safety and efficacy of combined dextroamphetamine (Dexedrine) and transcranial direct current stimulation (tDCS) with melodic intonation therapy (MIT) for treatment of aphasia after stroke.
- Trial name
- NCT02514044
- Testing
- Dexedrine, Active tDCS, Speech Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Health Science Center, Houston
Type 2 Diabetes, Coronary Heart Disease
NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)
PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type…
- Conditions
- Type 2 Diabetes, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Disease
- Trial name
- PREMAP (NCT07820800)
- Testing
- Digital health interventions
- Where
- Finland
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Chronic Stroke Patient
Efficacy of Swiss Ball Exercises Versus Kinesthetic Training for Improving Balance and Functional Mobility in Chronic Stroke Patients.
Stroke is one of the leading causes of long-term disability and commonly results in impaired balance, reduced trunk control, and difficulty in functional mobility.
- Trial name
- Not any (NCT07587463)
- Testing
- Swiss Ball Exercise Training, Kinesthetic Training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Nisha Fazal
Cerebrovascular Accident (CVA), Chronic Disease
Upper Limb Task-Oriented Rehabilitation With Robotic Exoskeleton for Hemiparetic Stroke Patients
The aim of this study is to evaluate the effects of an assisted rehabilitation treatment through a robotic exoskeleton device on the functional recovery in a group of patients with hemiparesis from lesion of the first motor…
- Conditions
- Cerebrovascular Accident (CVA), Chronic Disease, Stroke Rehabilitation
- Trial name
- RH-LEXOS (NCT03319992)
- Testing
- Upper Arm Rehabilitation Light Exoskeleton (RH-LEXOS)
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Post-ischemic Stroke
Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.
This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER.
- Trial name
- MILESTONE℠ (NCT02422940)
- Testing
- dalfampridine-ER 7.5 mg, dalfampridine-ER 10 mg
- Where
- 66 sites in United States, Canada
- Volunteers
- 294 people
- Sponsor
- Acorda Therapeutics
Chronic Stroke Patient
Relationship Between Balance, Arm Function and Body Awareness in People With Stroke
Stroke is one of the leading causes of long-term disability worldwide and is frequently associated with impairments in balance, upper extremity function, and body awareness.
- Trial name
- NCT07652710
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Baskent University
Patients in Minimally Conscious State After a Severe Brain Injury
tDCS on Precuneus in MCS: Repeated Stimulations
In this study researchers will apply transcranial direct current stimulation (tDCS) for 5 consecutive days in chronic patients in minimally conscious state (MCS).
- Trial name
- NCT02702362
- Testing
- transcranial direct current stimulation
- Volunteers
- 33 people
- Sponsor
- Hangzhou Normal University
Stroke, Motor Activity
Evaluation of a Video-ludic Re-education of the Paretic Upper Limb in Chronic Hemipartic Patients Post Cerebral Vascular Accident
The aim of this randomized controlled study with stroke patients is to demonstrate that a re-education with interactive table with instrumented objects delivering sensory feedback and serious game improve certain motor functions…
- Trial name
- ERGOTACT (NCT03166020)
- Testing
- Rehabilitation
- Where
- 2 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke), Age Between 18-75 Years
Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
The purpose of this study is to evaluate changes in strategies of hemiparetic upper limb movement in chronic stroke patients following rehabilitation using the "Nintendo Wii".
- Trial name
- WII (NCT01806883)
- Testing
- WII Rehabilitation, Traditional rehabilitation
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Paresis
Hemiparetic Arm Robotic Mobilization With Non Invasive Electrical Stimulation
The two cerebral hemispheres find themselves in a state of balanced mutual inhibition. A stroke with involvement of motor function leads to a reduced excitability in affected hemisphere M1 and to an increased excitability of…
- Conditions
- Stroke, Paresis, Upper Extremity Paralysis
- Trial name
- hARMonies (NCT03026712)
- Testing
- Real dual tDCS + Robotic Arm Therapy
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke
Neurostimulation Exosuit Augmented Training (NEAT) in the Clinic
The primary goal of this study is to understand the feasibility and rehabilitative effects of a Neurostimulation Exosuit Augmented Training (NEAT) program designed to provide high-intensity gait training in progressively…
- Trial name
- NCT07218107
- Testing
- Neurostimulation Exosuit
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Boston University Charles River Campus
Chronic Stroke
Neuroimaging Biomarkers Toward a Personalized Upper Limb Action Observation Treatment in Chronic Stroke Patients
Much recent interest was raised by the use of Action Observation Treatment (AOT) in stroke patients rehabilitation. AOT, well-grounded in neurophysiology, is an updated approach, based on mirror neuron system (MNS) used to…
- Trial name
- BE-TOP (NCT04047134)
- Testing
- Action Observation Treatrment, Observation of videos with Non Motor contents
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS San Raffaele
Stroke, Intervention
The Effectiveness and Mechanism of Character Strengths-based STEP Programme on Rehabilitation of Stroke Patients
There is an urgent need for educational and psychological adjustment to stimulate the post-stroke patients' motivation to actively carry out rehabilitation.
- Conditions
- Stroke, Intervention, Rehabilitation, Depression
- Trial name
- STEP (NCT05738499)
- Testing
- Character strengths-based structured treatment and education programme (CSSTEP), Structured treatment and education programme (STEP)
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Peking University
Chronic Ischemic Stroke, Balance Impairment
Effect Of Task-Specific Training With And Without Biofeedback On Balance And Risk Of Falls In Chronic Ischemic Stroke Patients Of Central Lahore, Pakistan
This randomized controlled trial aims to evaluate the effects of task-specific training with and without biofeedback compared to conventional physical therapy on balance and fall risk in chronic ischemic stroke patients in…
- Conditions
- Chronic Ischemic Stroke, Balance Impairment, Risk of Fall
- Trial name
- TST-BIO-STROKE (NCT07125157)
- Testing
- Task-Specific Training with Biofeedback, Task-Specific Training without Biofeedback, conventional stroke rehabilitation
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Syed Ali Behram Subazwari
Chronic Stroke
Brain Stimulation and Robotics in Chronic Stroke Motor Recovery
Motor skill training and transcranial direct current stimulation (tDCS) have separately been shown to alter cortical excitability and enhance motor function in humans.
- Trial name
- NCT03562663
- Testing
- Transcranial direct current stimulation, Upper extremity robotics
- Volunteers
- 82 people
- Sponsor
- Burke Medical Research Institute
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study
The CLIMATE Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific efforts, somatosensory amplification, self-efficacy, health…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE (NCT05961163)
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cerebrovascular Accident
Task-Oriented Aerobic Exercise Training in Chronic Stroke Patients
The study is designed to investigate (1) the effects of task-oriented aerobic exercise training on cardiorespiratory fitness, cerebral blood flow, oxygenation, functional performance, and physical activity in patients with…
- Trial name
- NCT00931671
- Testing
- Exercise training
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
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