Clinical trials: Stroke Assessment
Atrial Fibrillation, Atrial Flutter
Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation
The trial seeks to determine if apixaban, an investigational anticoagulant (blood-thinner) is as effective as standard therapy (warfarin) in preventing stroke and systemic embolism in subjects with atrial fibrillation and risk…
- Trial name
- ARISTOTLE (NCT00412984)
- Testing
- warfarin, apixaban
- Where
- 1,111 sites in United States, Argentina and 39 more
- Volunteers
- 20,976 people
- Sponsor
- Bristol-Myers Squibb
Stroke, Acute, Stroke
Evaluation of Small Vessel Disease by 3D-rotational Angiography
This study is aimed to elucidate the factors affecting the remodeling process of arteriolosclerosis under current practice recommendations.
- Conditions
- Stroke, Acute, Stroke, Small Vessel Cerebrovascular Disease, Ischemic Stroke
- Trial name
- NCT04611906
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- Chinese University of Hong Kong
Hemiplegia
Measurement by 2D Ultrasound of the Pennation Angle and Elasticity of Gastrocnemius Muscle
Hemiplegic adults after stroke (stroke), children and adolescents with cerebral palsy (CP) have both muscles spastic and paresis.
- Trial name
- NCT02549807
- Testing
- Muscle elasticity measure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke
Enhanced Mirror Therapy for Improving Brain Reorganization and Function in Stroke
This research aims to test the methodological procedures and obtain preliminary results regarding the therapeutic and cost-effectiveness of enhanced mirror therapy relative to standard mirror therapy for improving brain…
- Trial name
- NCT04749199
- Testing
- Enhanced mirror therapy, Standard mirror therapy
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Coronary Artery Disease
Assessment of Coronary Artery Disease in Stroke Patients
This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.
- Trial name
- ACADIS (NCT01850693)
- Where
- South Korea
- Volunteers
- 1,657 people
- Sponsor
- Seoul National University Hospital
Stroke, Traumatic Brain Injury
Informal Caregivers ANSWERS-VA
The purpose of this study is to determine the effectiveness of the ANSWERS- VA intervention (Acquiring New Skills While Enhancing Remaining Strengths for Veterans) while also determining it's cost effectiveness in the stroke and…
- Trial name
- NCT02398409
- Testing
- ANSWERS - Acquiring New Skills While Enhancing Remaining Strengths, Control
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- VA Office of Research and Development
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are severe clinical conditions that, despite advances in therapeutics over the past 20 years, lead to serious morbidity and…
- Trial name
- NCT05618093
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Sponsor
- University of California, Los Angeles
Physical Performance, Gait and Physiological Expenditure Index in Stroke Patients
the Instant Effect of Rigid and Kinesio Taping Techniques in Stroke Individuals With Foot Drop
Stroke individuals with foot drop experience poor physical performance and walking problems. Physiological energy consumption also increases due to balance and walking problems.
- Trial name
- NCT06608615
- Testing
- Kinesio Taping, Rigid Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kırıkkale University
Diabetes Mellitus, Microvascular Coronary Artery Disease
Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention.
This study is designed to test the hypothesis that ticagrelor is superior to clopidogrel, in improving coronary microvascular function, as measured by coronary flow reserve (CFR) in patients with T2DM at high risk of…
- Trial name
- AUGEAS (NCT04069234)
- Testing
- Ticagrelor, Clopidogrel
- Sponsor
- Region Skane
Stroke, Equinovarus Foot
Evaluation of Percutaneous Cryoneurotomy Compared to Surgical Open Neurotomy for the Management of Equinovarus Foot Deformity in Patients With Refractory Lower Limb Spasticity After Stroke
CRYOSTROKE study is designed : to compare the efficacy and safety of percutaneous CryoNeurotomie (CN) versus surgical neurotomy (SN) on spasticity, 90 days after intervention, in post-stroke patients presenting with spastic…
- Conditions
- Stroke, Equinovarus Foot, Refractory Lower Limb Spasticity
- Trial name
- CRYOSTROKE (NCT06726434)
- Testing
- Surgical neurotomy (SN), Cryoneurotomy (CN)
- Where
- 7 sites in France
- Volunteers
- 114 people
- Sponsor
- Poitiers University Hospital
Microemboli, Stroke
A Multicenter Study to Optimize Microembolic Signal Classification Based on Double--Blind Multiparametric Assessment by Human Experts Using an Universal Graphical Interface [MESOMEGA]
Microembolic signals (MES) is a powerful predictor of future embolic events. This study aims to develop and validate a accurate model of classification of MES obtained by transcranial Doppler.
- Conditions
- Microemboli, Stroke, Transcranial Doppler Ultrasound
- Trial name
- MESOMEGA (NCT07172165)
- Testing
- Expert double-blind evaluation
- Where
- Portugal
- Volunteers
- 850 people
- Sponsor
- Universidade do Porto
Spasticity, Post-Stroke
A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity
Botulinum toxin A (GSK1358820) is a sterile, purified type A botulinum neurotoxin complex. In Japan, 240 units of botulinum toxin A are approved as a maximum dose per administration for upper limb spasticity.
- Trial name
- NCT03261167
- Testing
- Botulinum toxin A (GSK1358820)
- Where
- 38 sites in Japan
- Volunteers
- 124 people
- Sponsor
- GlaxoSmithKline
Stroke
Reliability and Validity Study for SWE of Shoulder Muscles in Persons After Stroke.
This study aims 1. To examine the reliability of SWE assessment in the shoulder muscles of persons after a stroke. 2. To assess if differentiation can be made between the hemiplegic (HP) and non-hemiplegic (NHP) side and between…
- Trial name
- SWE_stroke (NCT04581551)
- Testing
- SWE assessor 1, SWE assessor 2, Stretch intervention
- Where
- 2 sites in Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement
Neuropsychological and Neuroimaging Evaluation of the Cognitive Impairment in Aortic Valve Replacement (ARTiCO)
OBJECTIVE: To evaluate changes in cognitive performance in the early postoperative (1 month) and late (1 year) postoperative period in patients undergoing aortic valve replacement (SVAo) with surgery (SVA_Q) or transcatheter…
- Conditions
- Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement, Surgical Treatment, Cognitive Impairment
- Trial name
- ARTiCO (NCT05235529)
- Testing
- Aortic valve replacement, TAVI
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Germans Trias i Pujol Hospital
Cerebral Infarct, Neurological Morbidity
Evaluation of Cerebral Parenchymal Changes in Patients Undergoing Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest Using Diffusion MRI
Deep hypothermic circulatory arrest (DHCA) (18 degree) without cerebral perfusion is a safe technique. Resarchers use this technique in patients with proximal aortic pathologies.
- Conditions
- Cerebral Infarct, Neurological Morbidity, Neurological Complication
- Trial name
- NON (NCT04755439)
- Testing
- DHCA
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Stroke, Brain Injuries, Traumatic
The Effects of Lifebloom One on Physical Activity After Acquired Brain Injury
The goal of this clinical trial is to evaluate the effects of Lifebloom One in people who have suffered a stroke or a traumatic brain injury.
- Trial name
- LBO_LCA (NCT05977270)
- Testing
- Lifebloom One
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Lifebloom
Stroke, Hip Fractures
Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward
The aim of this study is to investigate the effectiveness of our developed week-treatment program GAPP, on strength, balance, speed, functionality and cognition, with the main goal to achieve a better independence for activities…
- Conditions
- Stroke, Hip Fractures, Abdominal Injury, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT03109483
- Testing
- Geriatric Activation Program Pellenberg
- Where
- Belgium
- Volunteers
- 111 people
- Sponsor
- KU Leuven
PHYSICAL THERAPY TECHNIQUES
Robotic Constraint Lokomat Training for Gait Rehabilitation in Patients with Stroke
The aim of this study is to investigate the effect of a lokomat training on gait performance in Saudi females with stroke. Design: A-Single blind randomized controlled trial.
- Trial name
- NCT05485727
- Testing
- The Lokomat® Pro Hocoma USA & Conventional physical therapy, Conventional Physical Therapy
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- Umm Al-Qura University
Type 2 Diabetes, Stroke
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men During Hypoglycemia
Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence world wide with an increased risk of myocardial infarction and stroke.
- Conditions
- Type 2 Diabetes, Stroke, Myocardial Infarction
- Trial name
- NCT00418288
- Testing
- glucagon-like-peptide-1
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stroke, Tele-rehabilitation
Telerehab Exerbrain: Bridging Physical and Cognitive Therapy in Stroke
The goal of this clinical trial is to learn if a web-based exercise and cognitive training (physical-cognitive) program works to improve movements and brain function in adults with long-term stroke.
- Conditions
- Stroke, Tele-rehabilitation, Exercise, Motor Abilities
- Trial name
- NCT07446062
- Testing
- Web-Based Physical-Cognitive Telerehabilitation Exergaming
- Volunteers
- 52 people
- Sponsor
- Chiang Mai University
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