Clinical trials: Stroke Volume
Cardiac Output, Stroke Volume
Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain
The goal of this observational study was to better understand the impact of increased plasma volume on later exercise in hypoxia. Investigators examined young, healthy, males who regularly participated in aerobic exercise.
- Trial name
- NCT05800808
- Testing
- High Intensity Intervals, Moderate Exercise
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Healthy Adult
Ivabradine for Heart Rate Reduction During Exercise in Healthy Adults
During exercise, working muscles require more oxygen. The heart meets this demand in two ways: by beating faster (heart rate) and by pumping more blood with each beat (stroke volume).
- Trial name
- NCT07717710
- Testing
- Ivabradine (single oral dose)
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hemorrhage
Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume
This study is designed to validate implementation of the CRI algorithm in the CypherOx CRI system. Healthy human subjects will undergo progressive reduction in central blood volume to the point of hemodynamic instability (defined…
- Trial name
- NCT01935427
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Flashback Technologies
Stroke Volume, Cardiovascular Diseases
Heart Ultrasound by Emergency Medicine Residents as an Estimate of Heart Function
The purpose of this research is to better understand the use of heart ultrasounds to estimate heart function.
- Trial name
- BES2T (NCT05506059)
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- The Guthrie Clinic
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Laparoscopic Surgery
The Use of Tidal Volume Challenge of Dynamic Parameters During Laparoscopic Surgery
Laparoscopy is increasingly used for major abdominal and pelvic surgery. As this approach is also recommended in elderly patients with serious comorbidities, optimal fluid therapy guidance during this procedure is important.
- Trial name
- NCT03467711
- Testing
- tidal volume challenge, volume expansion
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Healthy Subjects
Interval Training and Resting Metabolism
It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational…
- Trial name
- NEAT (NCT01313468)
- Testing
- 1 x 4 minute interval, 4 x 4 minutes Intervals, Moderate continuous Training
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Diastolic Function, Cardiac Output
Impact of Pacing Mode and Diastolic Function on Cardiac Output
Background It is known from previous research that in patients with complete AV (atrioventricular) block and pacemaker stimulation stroke volume and cardiac output are higher with AV-synchronous than with AV-dyssynchronous…
- Conditions
- Diastolic Function, Cardiac Output, Pacemaker Stimulation Mode, Stroke Volume
- Trial name
- PADIAC (NCT04068233)
- Testing
- Pacemaker stimulation mode
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital
Lipodystrophy
Intraoperative Fluid Management of Liposuction , Cardiometry Versus Rohrich Formula
The aim of the study is to compare the hemodynamic parameters of fluid resuscitation using Rohrich formula to cardiometry guided stroke volume variation in patients undergoing large volume liposuction surgery .
- Trial name
- NCT05402982
- Testing
- Electrical Cardiometry (EC) ICON, Rohrich formula
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahmed Abdel Wahed Ali
Hemodynamic Monitoring
Evaluation of the UltraTrac System as a Non-Invasive Monitor of Hemodynamic Parameters
This study will test the use of the UltraTrac™ system, a small, noninvasive device that uses electrodes on the skin and a small ultrasound sensor to provide measurements of cardiac function in a wide of subjects.
- Trial name
- NCT07862608
- Testing
- Noninvasive Hemodynamic Monitoring System
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- AcQumen Medical, Inc.
Stroke Volume Variation, Diastolic Dysfunction
Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors
This investigator initiated, prospective, observational, single-center study is designed to assess whether dynamic monitors of cardiac function such as stroke volume variation (SVV) that have been shown to predict volume…
- Trial name
- NCT04177225
- Testing
- Trans thoracic Ultrasound Examination, Intravenous fluid administration
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Atelectasis
Effect of Hyperoxia and Hypergravity on Lung Ventilation and Perfusion
The primary aim of this project is to get further knowledge on the effects of + Gz accelerations and hyperoxia on lung ventilation in humans.
- Trial name
- NCT01993394
- Testing
- hypergravity, gas mixture
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stroke
Evaluating the Effects of Hormone Replacement Therapy on Brain Function (The WHIMS-MRI Study)
A silent stroke is a type of stroke that does not produce any severe symptoms, but may slightly affect memory or thinking abilities.
- Trial name
- WHIMS-MRI (NCT00739869)
- Where
- United States
- Volunteers
- 1,426 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure
Necklace-Shaped Sensor for Non-Invasive Monitoring of Stroke Volume and Cardiac Output
Study will compare measurements made with Necklace device for stroke volume/cardiac output with values from a FDA-approved reference device. The gold standard that will be used is Cardiac MRI.
- Trial name
- NCT02719301
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Baxter Healthcare Corporation
Hemorrhage
Comparison of Physiological Variables During Blood Donation
The investigators have developed a system based on a pulse oximeter, a tablet, and an algorithm running on the tablet that analyzes the pulse oximeter waveform.
- Trial name
- NCT02029807
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypotension
Norepinephrine and Phenylephrine, Which Better for Elderly?
this is a prospective, double-blinded and single-center study. this study is based on the Stroke volume variation fluid guided therapy, to compare the effects of norepinephrine and phenylephrine in treating perioperative…
- Trial name
- NCT04067817
- Testing
- norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
Cardiac Function
Cardiac Stroke Volume at Rest and During Different Exercise Intensities
The main aim of the present investigation is to study cardiac function in different exercise intensities in healthy human subjects.
- Trial name
- SVproject (NCT04287114)
- Testing
- Acute exercise
- Where
- 2 sites in Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Difference in Measured Results Using Four Different Strokevolume Measurements Simultaneously.
Real-time Comparison of Left Ventricular Strokevolume Measurement by Four Different Methods
Real-time comparison of three different bedside strokevolumemeasurements (arterial waveform analysis, eosofageal doppler and 2D transthoracal ultrasound) validated against cardiac magnetic resonance imaging (CMRI)
- Trial name
- FourComp (NCT01791283)
- Testing
- Arterial waveform analysis, esofageal doppler, transthoracal cardiac ultrasound, Cardiac magnetic resonance imaging.
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping