Clinical trials: Study Protocol Feasibility
Overdose
SOONER Feasibility Study Protocol
Opioid Overdose Education and Naloxone Distribution programs (OEND) involve training and equipping people who are likely to be bystanders to opioid overdose to recognize and respond to opioid-related emergencies by activating…
- Trial name
- SOONER (NCT03821649)
- Testing
- SOONER Training and Naloxone Kit Kit, Community or Hospital-Based Training
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Intracerebral Hemorrhage
Safety and Feasibility Study of Targeted Temperature Management After ICH
Though TTM is ubiquitously used in the neuro-intensive care unit, there is limited experience with the use of TTM after intracerebral hemorrhage (ICH), the most devastating type of stroke.
- Trial name
- TTM-ICH (NCT01607151)
- Testing
- Normothermia, Hypothermia
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Gastrointestinal Diseases
Gastrointestinal Myoelectric Activity Protocol, the G-Tech EEnG Protocol
A feasibility study for monitoring and recording gastrointestinal (GI) myoelectric activity in subjects with suspected or diagnosed irritable bowel syndrome (IBS) and reports of GI pain and asymptomatic subjects without IBS and…
- Trial name
- NCT01697397
- Testing
- Recording of Myoelectric Signals
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- G-Tech Corporation
Lung Non-Small Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use
This trial studies how well an enhanced tobacco intervention protocol (ETIP) works compared to standard treatment in helping head and neck and lung cancer patients starting treatment to reduce cigarette use.
- Trial name
- NCT04694846
- Testing
- Nicotine Replacement, Bupropion Hydrochloride Controlled-release, Varenicline
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Thomas Jefferson University
Chronic Low-back Pain
A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain
The aim of this randomized controlled trial is to evaluate the feasibility and effectiveness of providing an e-Health rehabilitation program through a web platform performing electroanalgesia and an exercise program following the…
- Trial name
- NCT04283370
- Testing
- Home Rehabilitation Program, e-Health program
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad de Almeria
Type2 Diabetes
Low-Carb/Time-restricted Feeding Protocol in Insulin-Using Type 2 Diabetics
The current paradigm of Type 2 Diabetes treatment relies heavily on expensive pharmacotherapy even though lifestyle factors are at the root of the condition.
- Trial name
- NCT04558827
- Testing
- Low Carbohydrate Diet, Time Restricted Feeding
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Knee Osteoarthritis, Depression
Exercise Plus Duloxetine for Knee Osteoarthritis
This study evaluates the addition of duloxetine to aerobic exercise in the treatment of symptomatic knee osteoarthritis and depressive symptoms in adults.
- Trial name
- NCT04111627
- Testing
- Aerobic exercise, Duloxetine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Maryland, Baltimore
Pancreatic Cancer, Pancreatic Neoplasms
Pancreatic Cancer Screening Using the Enzeavour Assay in Japan
This nationwide, multicenter, prospective, single-arm interventional feasibility study evaluates the Enzeavour Pancreatic Cancer assay in routine health checkups and cancer screening in Japan.
- Trial name
- ENZEAVOUR FS (NCT07605819)
- Testing
- Enzeavour Pancreatic Cancer Assay
- Where
- 69 sites in Japan
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Cosomil, Inc.
Neurocognitive Decline, Feasibility
Comparison Between Analog Neurocognitive Tests Conducted by a Trained Test Leader Versus Self-administered Digital Tests
The study has a randomized crossover design including qualitative interviews of the participant's test experiences. Healthy participants, ≥60 years are eligible to participate in the study.
- Conditions
- Neurocognitive Decline, Feasibility, Costs, Interviews
- Trial name
- PICASU-Eq (NCT05253612)
- Testing
- Analog testing conducted by a trained test leader using, ISPOCD test battery, self-administered Mindmore digital cognitive screening battery
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Syncope
Ambulatory Post-Syncope Arrhythmia Protection Feasibility Study
The purpose of this study is to conduct an observational investigation of a novel care path used to manage emergency department (ED) presenting syncope patients on an outpatient basis.
- Trial name
- ASAP (NCT02188147)
- Testing
- Short Term Wearable Defibrillator
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- Zoll Medical Corporation
Clinical Decision Making, Patient-Centered Care
Feasibility and Preliminary Effectiveness of a Shared Decision-making Process
Background: Shared decision-making is a process where health professionals and patients work together through conversation and using tools to make the best possible decision for the person.
- Conditions
- Clinical Decision Making, Patient-Centered Care, Obesity, Chronic Kidney Diseases
- Trial name
- NCT05424809
- Testing
- Shared decision-making model
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Vall d'Hebron
Healthy Volunteers
Assessing the Feasibility of a Novel Dynamometry Protocol for Measuring Finger Extensor Strength
This study aims to evaluate the feasibility and reliability of a novel method for assessing finger extension strength using an adapted dynamometer, addressing the limitation of current hand grasp assessment protocols that focus…
- Trial name
- NCT07730008
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Adult Rhabdomyosarcoma, Lung Metastases
Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases
This pilot clinical trial studies intensity-modulated radiation therapy (IMRT) in treating younger patients with lung metastases.
- Conditions
- Adult Rhabdomyosarcoma, Lung Metastases, Metastatic Ewing Sarcoma, Previously Treated Childhood Rhabdomyosarcoma
- Trial name
- NCT01586104
- Testing
- intensity-modulated radiation therapy
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Stroke, Balance
Does a Group, Task-oriented Community-based Exercise Program Improve Everyday Function in People With Stroke?
After a stroke, people find it difficult to perform everyday activities independently, like getting dressed, preparing meals, and shopping, limiting their independence and requiring the assistance of a family member, friend or a…
- Conditions
- Stroke, Balance, Mobility Limitation, Activities of Daily Living
- Trial name
- NCT03122626
- Testing
- Together in Movement and Exercise (TIME) Program
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of Toronto
Moderate to Severe Dementia
Dementia Moves: Protocol for a Feasibility Study
Most long-term care (LTC) residents live with frailty and dementia and the proportion with more advanced cognitive impairment is increasing.
- Trial name
- NCT06400108
- Testing
- Dementia Moves
- Volunteers
- 16 people
- Sponsor
- Dalhousie University
Depression, Unipolar
Psychotherapy Feasibility Pilot of the Carolina Recovery From Depression Protocol
The goal of this clinical trial is to learn whether an single session intervention can reduce psychological impairment in adult individuals with moderate depression.
- Trial name
- CARED (NCT06590038)
- Testing
- Single Session Psychotherapy Intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute Myeloid Leukemia, Myelodysplastic Syndromes
COaching and Prehabilitation: Faisability Study in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
This faisability study aims to evaluate the adhesion of the patient to a multidisciplinary program (adapted physical activity, coaching and nutrition)
- Trial name
- COHABILIT (NCT03595787)
- Testing
- Coaching and Habilitation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Paoli-Calmettes
Lacrimal Duct Obstruction, Lacrimal Stenosis
A Feasibility Study to Develop a Protocol for Functional Lacrimal Magnetic Resonance Imaging
Watering eyes (epiphora) is a very common ophthalmic condition. It is frequently caused by dysfunction of the lacrimal (tear) drainage system which is the 'pipework' that takes tears from the eye to the nasal cavity.
- Trial name
- NCT03411889
- Testing
- MRI scanning
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Healthy Women
TMS-Induced LH Response in Healthy Women in Luteal Phase
The purpose of this research is to establish whether non-invasive Transcranial Magnetic Stimulation (TMS), can affect modulation of hormones such: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH).
- Trial name
- NCT07363421
- Testing
- Transcranial Magnetic Stimulation Active
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Breast Cancer
Homeopathic Protocol for Advanced Breast Cancer
The objective of this study is to conduct a feasibility study at Meir Oncology Institute examining whether patients with advanced breast cancer would follow a homeopathic protocol for three to six months.
- Trial name
- NCT02190539
- Testing
- Homeopathic treatment
- Where
- Israel
- Sponsor
- Meir Medical Center