Clinical trials: Study Protocol Feasibility
Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction
Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study
This study is designed to evaluate the safety, feasibility, and effectiveness of a 12-week eccentric exercise program for older adults with sarcopenia (muscle loss) or sarcopenic obesity and chronic heart failure (HF).
- Conditions
- Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction, Sarcopenia in Elderly, Sarcopenic Obesity
- Trial name
- ECLYPSE-HF (NCT06826963)
- Testing
- Aerobic eccentric intervention
- Where
- 2 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Universita di Verona
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Stroke
Brazilian Adaptation of an Intervention Developed in Ireland to Promote Healthy Lifestyle Behaviors Post-stroke: a Feasibility Study
Introduction: Low- and middle-income countries, such as Brazil, are most impacted by the high burden of recurrent stroke. These countries also lack structured interventions to promote the adoption of healthy lifestyle behaviors…
- Trial name
- NCT07119047
- Testing
- A Brazilian adaptation of the Irish intervention "iHELP Stroke"
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Minas Gerais
Ileus Postoperative, Nasogastric Tube
Feasibility and Safety of an Ileus Management Protocol for Postoperative Ileus After Abdominal Surgery
The goal of this clinical trial is to evaluate whether a standardized treatment algorithm, the Ileus Management Protocol (I-MAP), is feasible and safe for the management of patients who develop postoperative ileus (POI) within 30…
- Trial name
- NCT07194525
- Testing
- A standardized treatment algorithm for postoperative ileus after abdominal surgery, based on nasogastric tube output and including stepwise use of water-soluble contrast, imaging, and prokinetic medic
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Lausanne Hospitals
Emotion-Focused Therapy, Aging
Emotion, Aging, and Forgiveness: Protocol for a Feasibility of Randomized Controlled Trial
Over recent decades, Emotion-Focused Therapy, aging, and forgiveness have garnered significant attention in the field of psychology.
- Conditions
- Emotion-Focused Therapy, Aging, Forgiveness
- Trial name
- NCT06679452
- Testing
- Emotion-Focused Therapy
- Where
- Portugal
- Volunteers
- 70 people
- Sponsor
- University of Maia
Stroke, Upper Extremity Paresis
Mental Practice Protocol With Severe Upper Extremity Hemiparesis
This study aims to examine the acceptability of patients and occupational therapists in following a mental practice protocol and examine the effects of mental practice with individuals with severe upper extremity hemiparesis…
- Trial name
- MentalPractice (NCT05519306)
- Testing
- Mental Practice
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Adventist HealthCare
Resilience, Psychological, Older Adults (60 - 85 Years Old)
Resilience-Building Intervention for Older Informal Caregivers
The goal of this pilot study is to test whether a newly developed resilience-building program is feasible and acceptable for older adults who provide unpaid care to people with functional impairment in the community.
- Conditions
- Resilience, Psychological, Older Adults (60 - 85 Years Old), Community Dwelling, Informal Caregiver
- Trial name
- NCT07712744
- Testing
- Multicomponent Resilience-building Program, AI Chatbot and Telephone Follow-up Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Heart Failure, Self-care
mHealth Intervention to Support Self-care During the Hospital to Home Transition in Individuals With Heart Failure
This study is a pilot randomized controlled trial designed to evaluate the feasibility, acceptability, usability, and preliminary efficacy of a mobile health (mHealth) educational self-management intervention for individuals with…
- Conditions
- Heart Failure, Self-care, Transitional Care
- Trial name
- HF-mHealth (NCT07478081)
- Testing
- mHealth Educational Self-Management Application, Usual transitional care
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Universidad de la Sabana
Intervention
Protocol: Feasibility of an Online Intervention to Increase Awareness of Gynaecological Cancer in UK Students
In the UK more than 2500 young people are diagnosed with cancer each year, including gynaecological cancers) and almost a third will be diagnosed within accident and emergency departments.
- Trial name
- GoCheck (NCT07147283)
- Testing
- Educational film and volitional help sheet
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Pain After Surgery, Anxiety After Surgery
Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery
This study teaches participants who are having colorectal surgery how to use mindfulness to feel calmer and manage pain better. Participants will be randomized (like a flip of a coin) into one of two groups: Mindfulness…
- Trial name
- NCT07026786
- Testing
- Mindfulness Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University Hospitals Cleveland Medical Center
Post-Acute COVID-19 Syndrome, Biofeedback, Psychology
Prevention of Long Covid Syndrome
Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome.
- Conditions
- Post-Acute COVID-19 Syndrome, Biofeedback, Psychology, Quality of Life, Depressive Symptoms
- Trial name
- NCT05793736
- Testing
- Biofeedback training, Treatment as usual
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- University of Cagliari
Adult Rhabdomyosarcoma, Lung Metastases
Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases
This pilot clinical trial studies intensity-modulated radiation therapy (IMRT) in treating younger patients with lung metastases.
- Conditions
- Adult Rhabdomyosarcoma, Lung Metastases, Metastatic Ewing Sarcoma, Previously Treated Childhood Rhabdomyosarcoma
- Trial name
- NCT01586104
- Testing
- intensity-modulated radiation therapy
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Borderline Personality Disorder (BPD), Avoidant Personality Disorders
Physical Activity in the Management of Personality Disorders
The PANDA trial is studying whether two types of physical activity - a walking program and supervised karate training - are safe, acceptable, and possible for adults with certain personality disorders.
- Trial name
- PANDA (NCT07341438)
- Testing
- Karate, Pedometer-based walking, Treatment as usual (TAU)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Julie Midtgaard
Nursing Home Residents
Feasibility of Risk Sign Displays to Prevent Falls, Dehydration and Pulmonary Aspiration in Nursing Homes
BACKGROUND: Prior research has shown a relationship between dehydration, falls and pulmonary aspiration among older adults in nursing and health care facilities, which contributes to its loss of independence and quality-of-life.
- Trial name
- NCT03123601
- Testing
- Risk sign displays
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Campus Neurológico Sénior
Healthy Participants, Young Adults
VR for Hope: A Brief VR Self-help Protocol to Enhance Hope and Well-being in Young Adults
The objective of this study is to evaluate the feasibility of a brief self-help protocol based on immersive Virtual Reality (VR) to promote hope and psychological well-being in young adults while enhancing their mentalization…
- Trial name
- NCT07483762
- Testing
- VR for Hope intervention
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Rheumatic Arthritis
Intervention to Support Partners and Informal Caregivers of Frail RA-patients
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with pain, fatigue, functional limitations, and reduced quality of life.
- Trial name
- INSPIRE (NCT07442773)
- Testing
- Caregiver support
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Oral Mucositis
Feasibility Study of a Protocol to Treat Pediatric Oral Mucositis by Low-level Laser Therapy
Low Level Laser Therapy has been used for a few years in some pediatric hospital centers for chemo- and radiotherapy-induced oral mucositis care. It may promote ulceration's healing, limits mucositis severity and associated pain.
- Trial name
- PEDIALASE (NCT02604329)
- Testing
- "Oncolase Digi" therapy laser diode
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Toulouse
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Applying the Pathways and Resources for Engagement and Participation Protocol Among People With Muscles Dystrophies
Taking part in community activities is essential for health and well-being. Yet, it is highly restricted for young people with Duchenne and Becker Muscular Dystrophies (DBMD), especially as they grow into adulthood.
- Trial name
- NCT06540365
- Testing
- Pathways and Resources for Engagement and Participation (PREP)
- Volunteers
- 6 people
- Sponsor
- University of Haifa
Leadership
Evidence-based Leadership in Nurse Leaders-CH
This study protocol describes a randomised feasibility trial that will evaluate the feasibility and preliminary effectiveness of the training course to improve evidence-based leadership competencies among nurse leaders working in…
- Trial name
- EVILEAD-CH (NCT05244499)
- Testing
- Evidence-based leadership training, Conventional training
- Where
- 2 sites in China
- Volunteers
- 119 people
- Sponsor
- University of Turku
Caregiver Burden
Eye Movement Desensitization and Reprocessing Group Treatment for Caregivers of Pediatric Brain Tumor Patients
Caregivers of pediatric brain tumor survivors may develop high levels of psychological distress, mostly depression and anxiety, with effects comparable to those of a traumatic event.
- Trial name
- NCT06339814
- Testing
- Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol, Treatment As Usual
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea