Clinical trials: Study Protocol Feasibility
Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction
Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study
This study is designed to evaluate the safety, feasibility, and effectiveness of a 12-week eccentric exercise program for older adults with sarcopenia (muscle loss) or sarcopenic obesity and chronic heart failure (HF).
- Conditions
- Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection Fraction, Sarcopenia in Elderly, Sarcopenic Obesity
- Trial name
- ECLYPSE-HF (NCT06826963)
- Testing
- Aerobic eccentric intervention
- Where
- 2 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Universita di Verona
Diabetes Type 2
Peer Comparison-based Risk Communication
The study objective is to evaluate the feasibility of delivering a risk communication intervention, Peer comparison-based Risk Communication (PRICOM), in the primary care setting for adults with poor T2DM control.
- Trial name
- PRICOM (NCT06837428)
- Testing
- Peer comparison-based Risk Communication (PRICOM)
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- SingHealth Polyclinics
Post-Acute COVID-19 Syndrome, Biofeedback, Psychology
Prevention of Long Covid Syndrome
Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome.
- Conditions
- Post-Acute COVID-19 Syndrome, Biofeedback, Psychology, Quality of Life, Depressive Symptoms
- Trial name
- NCT05793736
- Testing
- Biofeedback training, Treatment as usual
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- University of Cagliari
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Breast Cancer Surgery, Locoregional Anaesthesia
Feasibility of a Standardized Fascial Plane Block Protocol for Breast Cancer Surgery
The goal of this observational study is to evaluate the feasibility of a standardized locoregional anesthesia protocol for patients undergoing breast cancer surgery under procedural sedation or adjunctive hypnosis.
- Conditions
- Breast Cancer Surgery, Locoregional Anaesthesia, Hypnosis, Fascial Plane Block
- Trial name
- FASTBREAST2026 (NCT07877740)
- Testing
- Standardized locoregional anesthesia protocol for breast cancer surgery
- Where
- Switzerland
- Volunteers
- 65 people
- Sponsor
- Hôpital Fribourgeois
Delirium - Postoperative
Effectiveness of Electroencephalography Guided Anesthesia
This study will use brain wave information, known as electroencephalography (EEG), to help guide anesthesia delivery during surgery.
- Trial name
- EEG Anesthesia (NCT07567729)
- Testing
- EEG-guided anesthesia training program for anesthesia providers, EEG-Guided Intervention
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stroke
Brazilian Adaptation of an Intervention Developed in Ireland to Promote Healthy Lifestyle Behaviors Post-stroke: a Feasibility Study
Introduction: Low- and middle-income countries, such as Brazil, are most impacted by the high burden of recurrent stroke. These countries also lack structured interventions to promote the adoption of healthy lifestyle behaviors…
- Trial name
- NCT07119047
- Testing
- A Brazilian adaptation of the Irish intervention "iHELP Stroke"
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Federal University of Minas Gerais
Chronic Pain
Mindfulness Online and Virtual Exercise (MOVE) Compared With Self-Management for Chronic Pain
The aim of this study is to assess the feasibility and acceptability of a combined Mindfulness Based Stress Reduction (MBSR) and exercise online programme compared to an online self-management guide.
- Trial name
- NCT04899622
- Testing
- MBSR, Exercise, Online Self-Management Guide
- Where
- Ireland
- Volunteers
- 96 people
- Sponsor
- Orla Deegan
Breast Cancer
Management of Cognitive Difficulties After Cancer Treatments in Women Treated for Breast Cancer: Feasibility Study (Step 1 of the Cog-Stim Protocol)
Investigator general objective is therefore to study and compare the benefit of several methods of management of cognitive difficulties reported by patients during treatment for breast cancer, among several treatments, offered…
- Trial name
- COG STIM (NCT04213365)
- Testing
- Cognitive stimulation sessions coupled with Adapted Physical Activity sessions.
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Francois Baclesse
Breast Cancer, Rehabilitation
Prehabilitation for Women Undergoing Pre-operative Chemotherapy for Breast Cancer
To assess recruitment rate, attrition, compliance with weekly exercise, smoking cessation, and quality of life with a multimodal prehabilitation protocol for women with breast cancer undergoing neo-adjuvant chemotherapy for…
- Conditions
- Breast Cancer, Rehabilitation, Neoadjuvant Therapy, Feasibility Studies
- Trial name
- NCT03564171
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- Sunnybrook Health Sciences Centre
Unspecified Adult Solid Tumor, Protocol Specific
Palliative Care Intervention in Patients With Solid Tumors Participating in Phase I Clinical Trials
Patients enrolled in phase I clinical trials could potentially benefit from palliative care concurrently, yet limited evidence is available to support such a change in care.
- Trial name
- NCT01612598
- Testing
- counseling intervention, quality-of-life assessment, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- City of Hope Medical Center
Anxiety, Post Traumatic Stress Disorder
Improving Mental Health in Forcibly Displaced Populations
This project aims to improve mental health support for Venezuelan migrants living in Lima, Peru, who often face challenges like anxiety, depression, and post-traumatic stress disorder (PTSD).
- Conditions
- Anxiety, Post Traumatic Stress Disorder, Depression
- Trial name
- NCT06635486
- Testing
- Adapted cognitive-behavioral (CBT) intervention
- Where
- Peru
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Emotional Disorder
Feasibility of "EmoGuía" to Guide and Personalize Psychological Treatments
The present project aims at testing the feasibility of an app-based system called "EmoGuía" for routine outcome monitoring of adult patients with emotional disorders while they are administered a self-applied online…
- Trial name
- NCT05109780
- Testing
- My EMI, Emotional Well-being + self-applied online transdiagnostic treatment
- Volunteers
- 30 people
- Sponsor
- Universitat Jaume I
Depression
A Feasibility and Preliminary Efficacy Study of an App-Based Physical Activity Intervention (MoodMover) for Depression
Exercise is recommended as a standalone treatment for mild-to-moderate depression in Canada. However, it's unclear how mental health practitioners can guide patients to structured, in-person exercise programs.
- Trial name
- NCT06573125
- Testing
- MoodMover
- Volunteers
- 36 people
- Sponsor
- University of British Columbia
Breast Neoplasms
Smart-phone Health Coaching Intervention to Promote Maintenance of Exercise in Breast Cancer Survivors:Protocol
While physical activity (PA) appears to play an important role in disease control and the promotion of long-term health and well-being of cancer survivors, the large majority of breast cancer survivors are not physically active.
- Trial name
- iMOVE (NCT02620735)
- Testing
- Fit bit Device, Exercise Only, Connected Wellness HealthCoach Software
- Where
- Canada
- Volunteers
- 114 people
- Sponsor
- University Health Network, Toronto
Anterior Cruciate Ligament Reconstruction
Knee Care @Home Programme Feasibility Trial
The main goal of this trial is to determine the feasibility of a randomized controlled trial for the Knee Care at Home Programme, rather than the effectiveness, for patients recovering from anterior cruciate ligament…
- Trial name
- NCT06152380
- Testing
- Knee Care @Home Programme
- Volunteers
- 56 people
- Sponsor
- University of Évora
Older People, Frailty
A Technology-based Intervention to Support Older Adults in Living Independently
The general objective of this study is to test the usability and efficiency of the SAVE prototype, a technology-based support for enabling older adults to keep their independent and active lives in their homes and maintain their…
- Trial name
- SAVE (NCT05626556)
- Testing
- SAVE system
- Where
- 3 sites in Hungary, Italy and 1 more
- Volunteers
- 80 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Brain Injuries, Brain Diseases
Treating Chronic Symptoms of Pediatric Acquired Brain Injury - a Feasibility Study
Children with acquired brain injury (ABI) often struggle with complex impairments, including cognitive (such as memory and attention), social, emotional and behavioral challenges.
- Conditions
- Brain Injuries, Brain Diseases, Family, Child
- Trial name
- CICI (NCT04186182)
- Testing
- CICI - Feasibility trial study group
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Colorectal Cancer, Surgery-Complications
Early Discharge After Robotic Colorectal Surgery (eRCS): a Prospective Observational Study
The enhanced recovery after surgery (ERAS) scheme has improved recovery of patients by addressing the surgical stress and enabling a proactive perioperative care which has proven to decrease postoperative complications and reduce…
- Trial name
- eRCS (NCT05408182)
- Testing
- Robotic colorectal resection with ERAS (or eRCS) perioperative care
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale di Camposampiero
T4 Colorectal Cancer, ERAS
Feasibility of ERAS Protocol in T4 Colorectal Cancer Patients
Patients diagnosed with T4 colorectal cancer represent a specific subgroup of colorectal patients, frequently composed of fragile patients whose advanced nature of the disease often requires a multi organ resection by an open…
- Conditions
- T4 Colorectal Cancer, ERAS, Colon Cancer, Fast Track Protocol
- Trial name
- NCT04466696
- Testing
- ERAS protocol
- Volunteers
- 82 people
- Sponsor
- University of Rome Tor Vergata