Clinical trials: Subarachnoid Block
Anesthesia, Adverse Effect
Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects.
- Conditions
- Anesthesia, Adverse Effect, Hypotension, Cesarean Section Complications
- Trial name
- NCT03706755
- Testing
- Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg
- Where
- Tunisia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Anesthesia, Spinal
Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section
A Randomized, Controlled, Double blind study aiming to evaluate the analgesic potentials and side effect profile of different dose levels of Dexmedetomidine added to subarachnoid bupivacaine in full-term pregnant women undergoing…
- Trial name
- NCT02365857
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacaine Only.
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Anaesthesia Induced Hypotension
Role of Ondansetron in Spinal Anaesthesia Induced Hypotension
The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.
- Trial name
- NCT06727201
- Testing
- Ondansetron (Zofran)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Dexamethasone Intravenous Versus Intrathecal in Spinal Anesthesia
The purpose of this study is to compare the the effect of intravenous and the intrathecal dexamethasone when added to spinal anesthesia in cesarean section.
- Trial name
- NCT05470530
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean Section, Spinal Anesthesia
Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension
Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe.
- Trial name
- NCT06327165
- Testing
- observation
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Pregnancy
Comparison Between Palpatory and Preprocedural Ultrasound Guided Techniques on Performance of Spinal Anesthesia
Pre-procedural ultrasound for Spinal \& Epidural anesthesia is now being increasingly performed worldwide. Pre-procedural ultrasound assessment of the spine has been shown to facilitate the placement of epidural anesthesia in…
- Trial name
- NCT01865955
- Testing
- Ultrasound, The spinal needle
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Patients with ASA Physical Status 1 - 2 Who Undergo Surgical Delivery (cesarean Section)
Bupivacaine Effectivity and Efficiency for Regional Spinal Anesthesia in Non-ERACS and ERACS Caesarean Section
The most widely used regional anesthesia technique in Indonesia today is regional anesthesia with the subarachnoid (spinal) blockade method.
- Trial name
- NCT06640816
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Anesthesia, Spinal
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia
It is aimed to investigate whether the perfusion index (PI) can predict hypotension after spinal anesthesia in elderly patients as much as in non-elderly patients.
- Trial name
- NCT06427382
- Testing
- Perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Spine Disc Herniation
Effects of Addition of Magnesium Sulfate in Spinal Anesthesia on Sensory-Motor Blocks and Postoperative Pain in Lumbar Disk Herniation Surgery
The purpose of this study is to Compare three methods of intrathecal bupivacaine; bupivacaine-fentanyl; bupivacaine-fentanyl-magnesium sulfate on sensory-motor blocks and postoperative pain in patients undergoing lumbar disk…
- Trial name
- NCT01843296
- Testing
- Magnesium Sulfate, Spinal Anesthesia, Bupivacaine
- Where
- Iran
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Analgesia
Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block
The objective of this study is to compare the efficacy of transversalis fascia plane block using bupivacaine and ketamine versus bupivacaine alone for pain management after cesarean section under spinal anaesthesia.
- Trial name
- TFBP (NCT06935669)
- Testing
- Ketamine, Bupivacaine, Bupivacain
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension, Spinal Anaesthesia
The Effects of Keeping the Patient in a Sitting Position for One Minute After Spinal Anesthesia
The aim of this study was to examine the effect of keeping the patient in a sitting position for 1 minute after spinal anaesthesia in elective caesarean operations, primarily on the formation of hypotension and secondarily on…
- Trial name
- NCT03834259
- Testing
- sitting position, supine position
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Umbilical Cord Blood, Cesarean Section Surgery
Effect of Delivery Time on Umbilical Cord Blood Gas Parameters in Cesarean Sections Under General and Spinal Anesthesia
The goal of this observational study is to evaluate the effect of neonatal delivery time on umbilical cord blood gas parameters in pregnant women undergoing elective cesarean section under general or spinal anesthesia.
- Conditions
- Umbilical Cord Blood, Cesarean Section Surgery, General Anesthesia, Spinal Anesthesia
- Trial name
- DELTA-CS (NCT07321041)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort
Pain, Anxiety
The Effect of the Stress Ball Used During Spinal Anesthesia on Pain and Anxiety
The aim is to determine the impact of the stress ball used during spinal anesthesia on pain and anxiety levels
- Trial name
- stressball (NCT06267196)
- Testing
- The use of a stress ball
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypotension, Cesarean Delivery
Can Augmentation Index (AIx) be Used to Predict Hypotension After Spinal Anesthesia?
A fall in blood pressure (hypotension) occurs in one third of spinal anesthetics administered to pregnant patients undergoing cesarean delivery.
- Trial name
- NCT00884026
- Testing
- AIx measurement with a Sphygmacor TM
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Anesthesia; Reaction
Comparison of Hyperbaric Prilocaine 2% 50 Mg and Hyperbaric Bupivacaine 0.5% 12.5 Mg Against Spinal Anesthesia Recovery Time in Cystoscopy Procedure
Data regarding the comparison of recovery time from spinal anesthesia between prilocaine and bupivacaine are still relatively limited.
- Trial name
- NCT05610007
- Testing
- Prilocaine
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hypotenstion, Cesarean Resection
Norepinephrine vs. Phenylephrine for Spinal Hypotension in Cesarean Section
This clinical trial was conducted to compare the effectiveness and safety of two medications-norepinephrine and phenylephrine-in treating low blood pressure (hypotension) that often occurs during spinal anesthesia for cesarean…
- Conditions
- Hypotenstion, Cesarean Resection, Anesthesia Spinal, Pregnancy Complications
- Trial name
- Norepinephrine (NCT07153601)
- Testing
- Norepinephrine 4mcg, Phenylephrine 50 mcg
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara