Clinical trials: Subarachnoid Block
Spinal Anesthesia
Hyperbaric Prilocaine 2% vs Hyperbaric Bupivacaine 0.5% in Caesarean Section
Comparison between effects of hyperbaric bupivacaine 0.5% vs Hyperbaric prilocaine 2% in spinal anesthesia of women undergoing elective caesarean section such as onset time of sensory and motor block, duration of sensory and…
- Trial name
- NCT06680167
- Testing
- Spinal anesthesia (heavy bupivacaine 0.5%), spinal anesthesia (hyperbaric Prilocaine 2%)
- Where
- Egypt
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Sohag University
Anesthesia; Adverse Effect, Spinal and Epidural
Paramedian Incidence Angles in Spinal Anaesthesia
The objective here is to quantify the number of punctures and redirections during routine practice in the anesthesiology department, verify the final angle of incidence and the sac-skin distance by ultrasound, and determine the…
- Trial name
- NCT07210892
- Testing
- Measurement of needle insertion angles
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Post-Surgical Complication
Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.
To study control of post spinal shivering in patients undergoing lower segment cesarean section using dexmedetomidine, tramadol and ketamine
- Trial name
- NCT05311722
- Testing
- Dexmedetomidine, Ketamine, Tramadol
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Hypotension, Cesarean Section Complications
Norepinephrine to Prevent Hypotension in Ceasrean Delivery
This study will be conducted on 40 healthy women having spinal anesthesia for elective cesarean delivery in the operating rooms at Menoufia university hospital.
- Trial name
- NCT05248932
- Testing
- Norepinephrine bolus, cardiometry, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Vomiting, Postoperative, Postoperative Complications
The Effect of Intravenous Granisetron and Ondansetron in Patients Undergoing Cesarean Section
This study compared the effects of prophylactic intravenous (IV) infusion of ondansetron and granisetron before the spinal anesthesia on hemodynamic parameters in patients undergoing elective cesarean section.
- Conditions
- Vomiting, Postoperative, Postoperative Complications, Hypotension
- Trial name
- NCT04613726
- Testing
- ondansetron, Granisetron, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Spinal Anesthesia, Epidural; Anesthesia
Bupivacaine With Epidural Volume Extension
In this study the investigator will address the efficacy of using low dose bupivacaine spinal anesthesia (SA) in combination with epidural volume extension (EVE) for patients undergoing short obstetric procedures.
- Trial name
- NCT03110003
- Testing
- 10 mg Bupivacaine, 5 mg Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775)
Ultrasound Versus Palpation for Determining Spinal Puncture Level in Cesarean Section
This study compares two methods of identifying the correct intervertebral level before performing spinal anesthesia in women undergoing elective cesarean delivery.
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Spinal (MeSH: D000775), Hypotension (MeSH: D007022)
- Trial name
- USG-SPINE (NCT07789756)
- Testing
- Preprocedural ultrasound level identification, Landmark palpation level identification
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Section
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a safer method than general.
- Trial name
- NCT03067896
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section, Spinal Anesthesia
Low Dose Hyperbaric Bupivacaine and Dexmedetomidine as an Adjuvant, Caesarean Section
The aim of this study is to evaluate the effectiveness of low dose scheme with dexmedetomidine as an adjuvant. Taking in consideration optimum intraoperative surgical conditions, best post-operative pain free experience, and more…
- Conditions
- Cesarean Section, Spinal Anesthesia, Dexmedetomidine
- Trial name
- NCT03775655
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Cardiac Arrythmias
Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).
- Trial name
- CaRDIO (NCT03716076)
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiac Output, Low
Cardiac Index Changes With Ephedrine, Phenylephrine, Ondansetron and Norepinephrine During Spinal Anesthesia
The purpose of the study is to evaluate the cardiac output changes after an intravenous bolus of ephedrine, phenylephrine, ondansetron or norepinephrine during a spinal anesthetic for a cesarean delivery.
- Trial name
- EPhON (NCT03421860)
- Testing
- cardiac output changes with "ephedrine", cardiac output changes with "phenylephrine", cardiac output changes with "ondansetron"
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Spinal Anesthesia
Effect of Vasopressors on Spinal Anaesthesia Induced Hypotension
160 pregnant patients will be enrolled in this study. Participants will divide in to 4 groups. Spinal anaesthesia will perform with 5% marcain heavy 2 ml+20 microgram fentanyl to the all patients.
- Trial name
- NCT03163914
- Testing
- Epinephrine, Norepinephrine, Phenylephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Anxiety, Surgery
Does Showing Video Information About Spinal Anesthesia Relieves Patient Anxiety?
Our primary aim is to compare the effect of pre-operative multimedia video information on perioperative anxiety and hemodynamic parameters.
- Conditions
- Anxiety, Surgery, Spinal Anesthesia
- Trial name
- NCT04387487
- Testing
- Multimedia video information
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chitwan Medical College
Cardiac Output
The Effect of Ondansetron on Cardiac Output in Elective Cesarean Deliveries
Ondansetron is a medication routinely given to mothers having cesarean deliveries to help prevent and treat nausea and vomiting.
- Trial name
- NCT01841606
- Testing
- Ondansetron, Normal saline
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Edema, Hip Fractures
Ultrasound in Evaluation of Preoperative Fluid Management of Hip Fracture Surgery Patients
Goal directed fluid therapy is a new standard surgical procedure which is successful in patients undergoing hip revision arthroplasty, There has been a reduction of postoperative complications, most importantly surgery with a…
- Trial name
- NCT05916599
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Pain
Effect of Shotblocker on Procedure-related Pain, Satisfaction and Comfort in Patients Receiving Spinal Anesthesia
Although spinal anesthesia, which is increasingly common today, is a fast and reliable method, many patients are afraid of this procedure due to their fear of needles.
- Trial name
- NCT06163027
- Testing
- Shotblocker, Shotblocker(Plasebo)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University