Clinical trials: Subarachnoid Block
Magnesium Infusion in Post-spinal Opioid Pruritis
Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence
Introduction: Adding opioids to local anesthetic solutions leads to enhanced anesthesia and provide postoperative analgesia. Intrathecaly injected opioids have some side effects, though. One of them is pruritus.
- Trial name
- NCT04160598
- Testing
- IV infusion, intrathecal fentanyl
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
IV Ketamine With Spinal Block
Effect of Intravenous Ketamine Combined With Spinal Anesthesia on Sensory Block Duration Compared to Spinal Anesthesia Alone in Lower Limb Surgeries in Geriatrics.
Effect of Intravenous Ketamine combined with Spinal Anesthesia on Sensory Block Duration compared to Spinal Anesthesia alone in Lower Limb surgeries in geriatrics:
- Trial name
- NCT07520487
- Testing
- Patients will receive 0.2 mg/kg IV of ketamine diluted to 5 ml followed by infusion 0.1 mg/kg/hr as a 20 ml solution, Patients will receive 5 ml of saline followed by infusion 0.1 ml/kg/hr as a 20 ml solution as a control group
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
VIRTUAL REALITY
The Effect of Virtual Reality Glasses on Anxiety During Surgery Under Spinal Anesthesia
The aim of the study is to evaluate the efficacy of virtual reality glasses on anxiety of the patients who underwent operations under spinal anesthesia during peroperative period.
- Trial name
- VR (NCT03475810)
- Testing
- Virtual Reality, Midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Derince Training and Research Hospital
Cesarean Delivery
Influence of Anesthetic Temperature on Cephalad Sensory Blockade With Spinal Anesthesia
Several factors influence the extension of anesthetic mixture during spinal anesthesia including anesthetic gravity, body position, drug volume, and drug-delivering velocity.
- Trial name
- ATOCEB (NCT00815022)
- Testing
- bupivacaine/fentanyl/morphine
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Nanjing Medical University
Orthopedic Surgery
Comparison of Pregabalin Versus Gabapentin as Pre-emptive Analgesic
There are extensive gaps in the local data considering pregabalin versus gabapentin as pre-emptive analgesics in patients undergoing orthopedic surgeries under spinal anesthesia.
- Trial name
- NCT07389551
- Testing
- Gabapentin, Pregabalin
- Where
- Pakistan
- Volunteers
- 142 people
- Sponsor
- Muhammad Aamir Latif
Anesthesia, ERAS
Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Randomized, Interventional ,Open labeled, Parallel Assignment and Superiority trial.
- Conditions
- Anesthesia, ERAS, Surgical Stomas, Ileostomy - Stoma
- Trial name
- SPIGERAS (NCT06226753)
- Testing
- Type of anaesthesia used
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Hypotension After Spinal Anesthesia
Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section
The goal of this clinical trial is to learn if drug ondansetron, used in lingual form, lowers the incidence of spinal anesthesia-induced hypotension in cesarean sections. It will also learn about the safety of drug ondansetron.
- Trial name
- NCT07037654
- Testing
- ondansetron lingual film
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Suez Canal University
High BMI
A Comparative Study of Supine Position and the Head Elevated Position on the Level of Sensory Block After Spinal Anesthesia in Morbidly Obese Parturient Undergoing Elective Cesarean Delivery
The sniffing position defined as neck flexion with upper cervical extension, is traditionally recommended for general anesthesia induction, as it improves laryngoscopic views.
- Trial name
- NCT06889337
- Testing
- head elevated laryngoscopy position by Oxford pillow
- Where
- Qatar
- Volunteers
- 90 people
- Sponsor
- Hamad Medical Corporation
Surgery Ambulatory
Spinal or Intravenous Dexmedetomidine in Ambulatory Surgery
The primary objective of this double blind randomized study is to determine the effect of dexmedetomidine on onset and duration of the sensory and motor block and on the influence on bladder function after spinal anesthesia with…
- Trial name
- NCT02282319
- Testing
- spinal dexmedetomidine 0.5 mcg, spinal chloroprocaine 40 mg, IV dexmedetomidine 0.5 mcg/kg
- Where
- 2 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Hypotension
Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Based on the data that DEX increases the TPR and may decrease the expression of serotonin the investigator conducted this study to test the hypothesis that the prophylactic intravenous infusion (IVI) of DEX can attenuate the…
- Trial name
- NCT03664037
- Testing
- Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Adult Patients With Spinal Anesthesia
Comparison of Successful Spinal Needle Placement Between Crossed Leg Sitting Position and Traditional Sitting Position
The study aimed to compare successful spinal needle placement between crossed leg sitting position and traditional sitting position in patients underwent urology surgery.
- Trial name
- NCT02766829
- Testing
- Cross leg sitting position, Traditional sitting position
- Where
- Indonesia
- Volunteers
- 211 people
- Sponsor
- Universitas Indonesia
Umbilical Cord Blood, Cesarean Section Surgery
Effect of Delivery Time on Umbilical Cord Blood Gas Parameters in Cesarean Sections Under General and Spinal Anesthesia
The goal of this observational study is to evaluate the effect of neonatal delivery time on umbilical cord blood gas parameters in pregnant women undergoing elective cesarean section under general or spinal anesthesia.
- Conditions
- Umbilical Cord Blood, Cesarean Section Surgery, General Anesthesia, Spinal Anesthesia
- Trial name
- DELTA-CS (NCT07321041)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Neonatal Hypoxia and Asphyxia
Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Patients were classified into two equal groups using the presence or absence of hypertension during pregnancy into: hypertensive group (BP>140/90) and normotensive group (BP≤140/90.
- Trial name
- NCT03461913
- Testing
- Cesarean section
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Post Operative Urinary Retention, Spinal Aneshtesia
Effect of IV Dexamethasone on Post-op Urinary Retention After Spinal Anesthesia
What is this study about? This study is testing whether a common medication called dexamethasone, given through a vein (IV) before surgery, can help prevent a problem called postoperative urinary retention (POUR).
- Trial name
- DEX-PUR (NCT07077850)
- Testing
- Dexamethasone (IV), Normal Saline (0.9% NaCl)
- Where
- Palestinian Territories
- Volunteers
- 1,084 people
- Sponsor
- Al-Quds University
Postoperative Pain
Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia
The aim of this work is to compare the hemodynamic and analgesic properties of Dexmedetomidine and Magnesium sulphate infusion in lower abdominal surgery.
- Trial name
- NCT03640390
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia Complication, Vasopressor
Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine
Background : Spinal anesthesia emerges as the preferred anesthesia technique for elective cesarean section . It offers a preferable alternative to general anesthesia because it provides better maternal safety and neonatal…
- Conditions
- Anesthesia Complication, Vasopressor, Cesarean Section Complications, Hypotension During Surgery
- Trial name
- NCT06498076
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Anesthesia, Obstetrical
The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia
Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined…
- Trial name
- NCT03164096
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Perioperative/Postoperative Complications
The Effects of Dexmedetomidine on Peroperative Shivering Incidence Under Spinal Anesthesia
The purpose of this study to compare the efficacy of intravenous or intrathecal dexmedetomidine on the incidence of shivering on patients who scheduled spinal anesthesia for elective surgery.
- Trial name
- NCT01921361
- Testing
- Levobupivacaine, Dexmedetomidine, sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
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