Clinical trials: Subarachnoid Block
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Anesthesia, Spinal, Orthopedic Procedures
Comparison of Low-Dose Versus Standard-Dose Hyperbaric Bupivacaine in Spinal Anesthesia
The goal of this randomized controlled trial is to determine whether low-dose hyperbaric bupivacaine provides better hemodynamic stability and postoperative recovery compared with standard-dose hyperbaric bupivacaine in elderly…
- Conditions
- Anesthesia, Spinal, Orthopedic Procedures, Postoperative Recovery in Elderly Patients, Hemodynamics
- Trial name
- NCT07684989
- Testing
- Low-Dose Hyperbaric Bupivacaine, Standard-Dose Hyperbaric Bupivacaine
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Mayo Hospital Lahore
Pregnant Women, Pain
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Over the past 15 years, cesarean delivery is most commonly performed under spinal anesthesia using hyperbaric bupivacaine which provides an adequate sensory and motor block.
- Conditions
- Pregnant Women, Pain, Hypotension
- Trial name
- NCT02973048
- Testing
- Hyperbaric bupivacaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Anesthesia, Spinal, Neurosurgery
Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery
The goal of this pilot clinical trial is to test the feasibility of conducting a randomized controlled trial that will examine the use of ropivacaine in the spinal anesthesia for patients undergoing elective 1- or 2-level lower…
- Conditions
- Anesthesia, Spinal, Neurosurgery, Ropivacaine, Bupivacaine
- Trial name
- SASS (NCT05824338)
- Testing
- Spinal anesthesia for lumbar surgery: ropivacaine, Spinal anesthesia for lumbar surgery: bupivacaine, General anesthesia for lumbar surgery
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Fraser Health
Knee Osteoarthritis, Hip Osteoarthritis
Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to…
- Trial name
- NCT03838874
- Testing
- Low-Dose Bupivacaine, Mepivacaine
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Mayo Clinic
Spinal Anesthesia
The Bupivacaine Dose Sparing Effect of Intrathecal Epinephrine
Intrathecal epinephrine has been known to increase the duration of spinal anesthesia, or increase the quality of anesthesia. However, there is still a controversy, and the mechanism of epinephrine is recently suggested as a…
- Trial name
- NCT01261078
- Testing
- epinephrine 25, Epinephrine 50, epinephrine 100
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul Medical Center
Return of Motor and Sensory Blockade, Anesthesia, Spinal
1% Chloroprocaine(PF) vs. Bupivacaine Spinals
The use of 1% Chloroprocaine (PF) spinal anesthesia will reduce the recovery times and discharge time of patients undergoing hemorrhoidectomies as compared to 0.75% bupivacaine spinal.
- Conditions
- Return of Motor and Sensory Blockade, Anesthesia, Spinal, Decrease Discharge Time Status Post Hemorrhoidectomy
- Trial name
- NCT03324984
- Testing
- 1% chloroprocaine, 0.75% bupivacaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Montefiore Medical Center
Retrograde Intrarenal Surgery
General Versus Spinal Anesthesia in RIRS
The impact of anesthesia type on Retrograde Intrarenal Surgery (RIRS) outcomes remains a subject of ongoing debate. Several studies have compared general anesthesia (GA) and spinal anesthesia (SA) in endourological procedures…
- Trial name
- NCT07664384
- Where
- Egypt
- Volunteers
- 252 people
- Sponsor
- South Valley University
Anesthesia, Spinal
Effect of Intrathecal Fentanyl on Spinal Anesthesia During Dexmedetomidine Infusion
Intravenous infusion of dexmedetomidine during procedure was known to be associated prolonged duration of spinal anesthesia. In patients receiving dexmedetomidine infusion during procedure, it has been not evaluated whether use…
- Trial name
- NCT03105115
- Testing
- fentanyl, bupivacaine only
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Cesarean Section Complications, Spinal Anesthesia
Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia
Comparison between prophylactic continuous variable infusion of phenylephrine (starting dose 0,5mcg/kg/min) and norepinephrine tartrate (starting dose 0,1mcg/kg/min) to prevent hypotension and maintain cardiac output under spinal…
- Trial name
- PHENAD (NCT03849508)
- Testing
- Norepinephrine, Phenylephrine
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Planned Cesarean Section
Acute Preoperative Stress and Hypotension After Spinal Anesthesia. SAS for "Salivary Amylase and Stress "
Spinal anesthesia is the technique of choice for planned cesarean section. It is associated with a high frequency of maternal hypotension.
- Trial name
- SAS (NCT01862055)
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patient Group With Alpha Blocker Use
Hemodynamic Effects of Alpha Blockers in Patients With Spinal Anesthesia
There is frequent use of alpha blockers in elderly patients with urological disorders. Various side effects are encountered due to the use of alpha blockers in the elderly age group.
- Trial name
- NCT06998537
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Izmir City Hospital
Shivering, Nausea and Vomiting, Postoperative
Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering
This is a randomized double blinded trial to determine if a small dose of dexmedetomidine can prevent and relieve nausea and shivering, two of the more common complaints after cesarean delivery.
- Trial name
- NCT03370562
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Causes of Spinal Failure
Causes of Spinal Failure in Cesarean Section
The main purpose of this research is to determine the causes of spinal anesthesia failures during cesarean section due to social, emotional and attitude factors towards surgery and to use this information to improve anesthesia…
- Trial name
- NCT06973486
- Testing
- psychometric scales
- Volunteers
- 128 people
- Sponsor
- Haseki Training and Research Hospital
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
Total Joint Arthroplasty
Utility of Indwelling Catheter in Orthopaedic Patients Receiving Spinal Anesthesia
A study measuring utility of indwelling bladder catheter placement in orthopaedic surgical patients receiving spinal anesthesia. Study will track clinical outcomes, patient satisfaction and cost efficacy.
- Trial name
- NCT01577823
- Testing
- Foley Catheter
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Hypotension
Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
Comparison of two practices of obstetrical services between the CHU of Clermont Ferrand and the HFME Lyon-Bron in the management of arterial hypotension during an elective cesarean section
- Trial name
- ARTEMIS (NCT05513066)
- Where
- 2 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Spinal, Prilocaine
Prilocaine for Spinal Anesthesia in Ambulatory Setting
The purpose of this study is to retrospectively analyze data from more than 3000 procedures, to better define the safety profile of spinal prilocaine and the incidence of complications and side effects.
- Conditions
- Anesthesia, Spinal, Prilocaine, Ambulatory Surgical Procedures
- Trial name
- NCT04161586
- Testing
- Prilocaine Hydrochloride
- Where
- Italy
- Volunteers
- 3,291 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Ruptured Cerebral Aneurysm, Subarachnoid Hemorrhage (SAH)
Barrow Ruptured Aneurysm Trial
With evolving endovascular technologies there is a growing debate centered on the relative safety and efficacy of the currently accepted alternatives for the treatment of ruptured cerebral aneurysms in the face of acute…
- Trial name
- BRAT (NCT01593267)
- Testing
- coil embolization, clip occlusion
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Vomiting, Nausea
Exteriorized Versus In Situ Uterine Repair at Cesarean Delivery
This study was undertaken to compare the two techniques (exteriorized vs in situ) of uterine repair with respect to patient comfort, hemodynamic changes, surgical time and blood loss, in patients undergoing elective CD under a…
- Conditions
- Vomiting, Nausea, Pain, Hypotension
- Trial name
- NCT00452972
- Testing
- Spinal Anesthesia
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
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