Clinical trials: Subarachnoid Block
Pruritus Caused by Drug
Intravenous Lidocaine for Treating Intrathecal Fentanyl Induced Pruritus
The study will assess efficacy of intravenous lidocaine 1 mg/kg diluted with 0.9% sodium chloride to a volume of 100 ml to suppress intrathecal fentanyl induced pruritus.
- Trial name
- NCT06243120
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Ain Shams University
Shivering, Post-Spinal Shivering
Intravenous Paracetamol Versus Magnesium Sulfate for Control of Shivering Following Spinal Anesthesia in Cesarean Section
Spinal anesthesia is widely used for cesarean deliveries, but shivering is a frequent complication that occurs in 40% to 60% of patients.
- Trial name
- NCT07855588
- Testing
- Paracetamol, Magnesium Sulfate
- Volunteers
- 90 people
- Sponsor
- Assiut University
Anesthesia, Cancer
Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial)
The use of intravenous lidocaine in continuous infusion in the perioperative period is associated with a reduction in postoperative pain scores, opioid use, incidence of nausea and vomiting, among other favorable outcomes.
- Trial name
- ELSA (NCT04741880)
- Testing
- Lidocaine IV, Saline
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Blood Pressure Measurement
Agreement of the Nexfin™ Monitor With Non-invasive Blood Pressure Measurement
Currently, BP is measured using an inflatable cuff wrapped around the patient's upper arm. This can be set to inflate every minute, but measurement may fail due to patient movement or shivering.
- Trial name
- Nexfin Pilot (NCT02447471)
- Testing
- Nexfin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Shivering, Hypothermia
Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal Anesthesia
Shivering is a common and distressing complication occurring in 40% to 60% of women undergoing cesarean section under spinal anesthesia.
- Conditions
- Shivering, Hypothermia, Cesarean Section, Spinal Anaesthesia
- Trial name
- NCT07855536
- Testing
- Dexmedetomidine, Meperidine, Normal Saline 0.9%
- Volunteers
- 99 people
- Sponsor
- Assiut University
Hip Fracture
Comparison of Three Analgesic Strategies for Hip Fracture Surgery
Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption.
- Trial name
- HIP-3B (NCT07676734)
- Testing
- Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Many previous studies have investigated the ability of various methods such as passive leg raising test , and inferior vena cava collapsibility index in predicting post-spinal hypotension, but none of them have succeeded in…
- Trial name
- NCT05991063
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Comparing Analgesic Effects of Wound Infiltration Using Bupivacaine, Tramadol, and Tramadol Plus Bupivacaine
The goal of this study's clinical trial is to compare in post-operative analgesic effectiveness of wound infiltration using bupivacaine, tramadol, and tramadol plus bupivacaine in patients undergoing elective cesarean section…
- Trial name
- NCT06076707
- Testing
- bupivacain-tramadol
- Where
- Ethiopia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Wollo University
we Study the Effect of Keeping the Patient Supine 2 Minutes After Spinal Anesthesia in Geriatric Groups
Delayed Supine Position Post-Spinal Compared With Immediate Supine Position in Geriatric Patients
Background: Geriatric patients undergoing femoral neck of fracture (FNOF) repair are highly susceptible to spinal anesthesia-induced hypotension.
- Trial name
- NCT07520695
- Testing
- 2 minutes setting post spinal anesthesia, immediate supine position
- Where
- Oman
- Volunteers
- 90 people
- Sponsor
- Sohar Hospital
Sedation; Aged; Hemodynamics
A Comparision of Midazolam-dexmedetomidine With Dexmedetomidine Alone for Hemodynamic Stability and Quality of Sedation in Elderly Patients Under Spinal Anesthesia
The purpose of this study is to compare midazolam-dexmedetomidine with dexmedetomidine alone for hemodynamic stability and quality of sedation in elderly patients under spinal anesthesia.
- Trial name
- NCT01979653
- Testing
- dexmedetomidine alone or dexmedetomidine + midazolam
- Where
- South Korea
- Sponsor
- Severance Hospital
Chills
Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
comparison of Dexmedetomidine And Ketamine For Control Of Shivering In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia.
- Trial name
- NCT05481281
- Testing
- Dexmedetomidine, Ketamine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Cesarean Section, Anesthesia, Obstetric
Evaluation of the Typical Spinal Block During Cesarean Delivery
This will be a prospective, observational, single-center study to evaluate the accuracy of sensory testing by blunt 16-gauge plastic cannula during the 15 minutes after spinal injection for predicting spinal failure.
- Trial name
- NCT06206044
- Testing
- Intrathecal 1.6 ml 0.75% bupivacaine in 8.25% dextrose combined with 15 mcg fentanyl and 150 mcg preservative-free morphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Meniscus Lesion
Femoral Blockade and Low-dose Spinal Anesthesia in Outpatient Knee Arthroscopy
The investigators of the current study aimed to evaluate the effect of spinal anesthesia with low dose bupivacaine combined with femoral blockade on duration of anesthesia and time of first analgesic requirement during…
- Trial name
- NCT02322372
- Testing
- Femoral blockade, Intrathecal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara University
Cesarean Section Complications, Spinal Anesthesia
Three Protocols for Phenylephrine Administration in Cesarean Delivery
The investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg)…
- Trial name
- NCT03302039
- Testing
- Single shot phenylephrine, Fixed infusion phenylephrine., Variable infusion phenylephrine.
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Cairo University
Anaesthesia
Landmark Guided Midline Versus Pre-procedural Ultrasound Guided Paramedian at L5S1 for Spinal Anaesthesia
Spinal anesthesia is widely performed using a surface landmark based 'blind' technique. Multiple passes and attempts while administering spinal anesthesia are associated with a greater incidence of post dural-puncture headache…
- Trial name
- NCT02189681
- Testing
- Conventional landmark guided midline spinal anaesthesia, pre-procedure ultrasound guided L5S1 paramedian spinal, spinal anaesthesia
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Cork University Hospital
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Adjuvants, Anesthesia, Subarachnoid Block
Intrathecal Nalbuphine Versus Intrathecal Tramadol in Subarachnoid Block for Lower Limb Orthopaedic Surgeries
This study compares the use of intrathecal nalbuphine versus intrathecal tramadol as adjuvant agents to local anaesthetics in subarachnoid block for lower-limb orthopaedic surgeries.
- Trial name
- NCT07294352
- Testing
- Intrathecal tramadol with spinal anesthsia, Intrathecal nalbuphine and spinal anesthesia
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Melatonin, Cognitive Dysfunction
Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
This study aims to evaluate the possible effect of melatonin on prevention of cognitive dysfunction in the postoperative period of elderly patients undergoing transurethral resection of the prostate (TURP) under spinal anesthesia
- Conditions
- Melatonin, Cognitive Dysfunction, Postoperative Complications, Prostate Hyperplasia
- Trial name
- NCT03966950
- Testing
- melatonin
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Pain, Cesarean Section
Comparison of the Time to the First Rescue Analgesic Among Parturients Receiving Intrathecal Additive Fentanyl or Intrathecal Fentanyl With TAP Block or TAP Block Alone for Elective Cesarean Sections Under Hyperbaric Bupivacaine Spinal Anesthesia
The postoperative pain management after cesarean section under spinal anestheisa is done using various modalities. The commonly used regimens are systemic NSAIDs/Opioids, USG guided TAP block or Intrathecal additive Fentanyl or…
- Trial name
- NCT05550597
- Testing
- Fentanyl HCl, Bupivacaine 0.25% Injectable Solution
- Where
- Nepal
- Volunteers
- 93 people
- Sponsor
- Nepal Mediciti Hospital
Intraocular Pressure, Spinal Anesthesia
Upper Extremity Position and Intraocular Pressure During Spinal Anesthesia: A Randomized Controlled Trial
This prospective randomized controlled trial evaluated the effect of two upper extremity positions on intraocular pressure (IOP) in adult patients undergoing surgery under spinal anesthesia.
- Conditions
- Intraocular Pressure, Spinal Anesthesia, Surgical Positioning
- Trial name
- UEP-IOP (NCT07424417)
- Testing
- Upper Extremity Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
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