Clinical trials: Submucosal Tumor of Gastrointestinal Tract
Gastric Cancer
Evaluation of the Efficacy and Safety of Indocyanine Green Tracing in 3D Fluorescent Laparoscopic Lymph Node Dissection for Gastric Cancer
Purpose of the study To evaluate whether the clinical efficacy of submucosal injection of indocyanine green tracer laparoscopic gastric cancer lymph node dissection is superior to that of laparoscopic gastric cancer lymph node…
- Trial name
- NCT06421220
- Testing
- Preoperative injection of indocyanine green
- Where
- China
- Volunteers
- 484 people
- Sponsor
- Qilu Hospital of Shandong University
Endoscopic Submucosal Dissection, Early Gastric Cancer
Efficacy and Safety Study of Endoscopic Submucosal Dissection for Early Gastric Cancer
The purpose of this study is to evaluate the safety and clinical effectiveness of ESD(Endoscopic Submucosal Dissection) for early gastric cancer analyzing short-term and long-term results of endoscopic treatment.
- Conditions
- Endoscopic Submucosal Dissection, Early Gastric Cancer, Multi-center, Single-arm Clinical Trial, Historical Control Group
- Trial name
- ESD (NCT01132469)
- Testing
- Endoscopic Submucosal Dissection
- Where
- South Korea
- Volunteers
- 1,158 people
- Sponsor
- National Evidence-Based Healthcare Collaborating Agency
Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST)
CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled Study
The investigators conduct a prospective, multicenter diagnostic trial primarily aimed at evaluating the value of contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) in differentiating gastrointestinal stromal tumors…
- Conditions
- Submucosal Tumor, Gastrointestinal Stromal Tumor (GIST), Leiomyoma
- Trial name
- NCT07106411
- Testing
- Endoscopic Ultrasound, Contrast-Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Huazhong University of Science and Technology
Colorectal Cancer, Indocyanine Green
Endoscopic Submucosal Injection of Indocyanine Green Before Laparoscopic Radical Resection for Colorectal Cancer
Prospective registry study of endoscopic submucosal injection of indocyanine green before laparoscopic radical resection for colorectal cancer
- Trial name
- NCT04207489
- Testing
- endoscopic submucosal injection of indocyanine green before laparoscopic radical operation of colorectal cancer
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jilin University
Early Gastric Cancer
Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer
The investigators compared the perioperative, oncological, functional and immunological outcomes of endoscopic submucosal dissection against laparoscopic assisted gastrectomy for treatment of early gastric cancer.
- Trial name
- LGE (NCT03136354)
- Testing
- Endoscopic Submucosal Dissection, Laparoscopic assisted Gastrectomy
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- Chinese University of Hong Kong
Colo-rectal Cancer
Efficacy of a Hemostatic Agent (PuraStat®) in Reducing Delayed Bleeding After Endoscopic Submucosal Dissection
The problem of delayed bleeding after endoscopic resection is becoming important due to the growing number of indications for anti-aggregation or anticoagulant treatment for cardiovascular reasons in the aging populations.
- Trial name
- NCT05031325
- Testing
- Endoscopic submucosal dissection with Purastat
- Where
- France
- Volunteers
- 288 people
- Sponsor
- Mathieu Pioche
Esophagus Cancer
Multicenter Cohort Study of ESD and Chemo-radiotherapy for High-risk Early-stage Esophageal Cancer
This multicenter, prospective observational cohort study has the potential to optimize individualized chemoradiotherapy regimen for early-stage esophageal cancer patients who have received endoscopic submucosal dissection.
- Trial name
- ESCORT (NCT06385717)
- Testing
- chemo-radiation
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Gastric Cancer
Effects of Ilaprazole on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone ESD.
This study compared Ulcer healing rate of Ilaprazole 20mg or Rabeprazole 20mg in the patients undergone Endoscopic Submucosal Dissection for Gastric Adenoma or Early Gastric Cancer and investigated Prevention of gastrointestinal…
- Trial name
- NCT02638584
- Testing
- Ilaprazole, Rabeprazole
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
Esophageal Neoplasms, Endoscopic Mucosal Resection
Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections
This is a randomized, single-center clinical trial that will compare the efficacy of two substances used in the submucosal cushion formation stage of endoscopic submucosal resections of early esophageal malignant neoplasms.
- Conditions
- Esophageal Neoplasms, Endoscopic Mucosal Resection, Hyaluronic Acid
- Trial name
- NCT06077981
- Testing
- Submucous Endoscopic Dissection with hydroxyethylamide, Submucous Endoscopic Dissection with Hyaluronic acid (TS-905 Blue Eye)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Endoscopic Submucosal Dissection, Gastric Neoplasm
Learning Curve for Gastric Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) for early gastric cancer is a widely accepted treatment option of expanded indication worldwide.
- Trial name
- NCT05265221
- Testing
- Endoscopic submucosal dissection
- Where
- South Korea
- Volunteers
- 356 people
- Sponsor
- Soonchunhyang University Hospital
Esophageal Cancer, Esophageal Dysplasia
Comparison of O-type Hybrid Knife and IT Knife in ESD
By combining injection and dissection capability together, O-type Hybrid knife could possibly shorten the endoscopic submucosal dissection procedure for upper gastrointestinal neoplasms.
- Conditions
- Esophageal Cancer, Esophageal Dysplasia, Stomach Cancer, Stomach Dysplasia
- Trial name
- NCT01760070
- Testing
- Hybrid knife, IT knife
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Robot Surgery, Endoscopic Submucosal Dissection (ESD)
Efficacy and Safety of Robot-assisted Endoscopic Submucosal Dissection for Colorectal Neoplasm
The objective of this study is to investigate the role of the flexible auxiliary single-arm transluminal endoscopic robot (FASTER) system in colorectal endoscopic submucosal dissection (ESD) and to validate its superiority over…
- Conditions
- Robot Surgery, Endoscopic Submucosal Dissection (ESD), Colorectal Neoplasms
- Trial name
- NCT06973083
- Testing
- FASTER-assisted ESD, Conventional ESD
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Shandong University
Pancreatic Cyst, Pancreatic Neoplasms
Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract
This study focuses on four different lesions: pancreatic cysts, lymph nodes near the gastrointestinal tract, pancreatic masses and GIST tumors.
- Conditions
- Pancreatic Cyst, Pancreatic Neoplasms, Pancreatic Adenoma, Pancreatic Cancer
- Trial name
- US-nCLE (NCT01770405)
- Testing
- Endoscopic ultrasound fine needle aspiration
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mauna Kea Technologies
Early Gastric Cancer, Gastric Adenoma
Effect of Midazolam Premedication on the Satisfaction Levels of Patients After Endoscopic Submucosal Dissection
Endoscopic submucosal dissection is commonly performed under light to moderate sedation, and minimizing patient movement is of key importance for successful outcome.
- Trial name
- NCT02504164
- Testing
- midazolam 0.02mg/kg, No premedication
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Endoscopic Submucosal Dissection, Colorectal Neoplasms
Early Feeding Versus Delayed Feeding After Colorectal Endoscopic Submucosal Dissection
Currently, there are no clear guidelines regarding the optimal timing for dietary restart after gastrointestinal endoscopic submucosal dissection (ESD).
- Trial name
- NCT06805123
- Testing
- Early feeding, Late feeding
- Where
- 5 sites in South Korea
- Volunteers
- 204 people
- Sponsor
- Pusan National University Hospital
Endoscopic Resection, Rectal Tumor
A Comparison of Endoscopic Synchronous Injection and Submucosal Dissection(ESISD) and Conventional Endoscopic Submucosal Dissection(CESD) for Granular Mixed Nodular Laterally Spreading Tumor in the Rectum (LST-G-M)
What is the study about? This study introduces and evaluates a new endoscopic technique called Endoscopic Synchronized Injection and Submucosal Dissection (ESISD).
- Trial name
- ESISD vs CESD (NCT07236827)
- Testing
- Endoscopic Synchronous Injection and Submucosal Dissection(ESISD), Conventional Endoscopic Submucosal Dissection(ESD)
- Volunteers
- 60 people
- Sponsor
- Taihe Hospital
Colorectal Neoplasms
Endoscopic Submucosal Dissection Versus Laparoscopic Resection for Early Colorectal Neoplasms
This is a prospective randomized trial that aimed to compare the short-term clinical outcomes and systemic inflammatory/cytokine responses of endoscopic submucosal dissection versus laparoscopic resection for early colorectal…
- Trial name
- NCT01112046
- Testing
- Endoscopic submucosal dissection, Laparoscopic resection
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Chinese University of Hong Kong
Esophageal Cancer
SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma
This is a study from Fujian Cancer Hospital Thoracic of Surgery Project, numbered as FJCHTOSP-1. Systematically mediastinal Lymph Node Dissection (SLD) Versus Non-Dissection Following Endoscopic Submucosal Dissection (ESD) for…
- Trial name
- NCT06979986
- Testing
- Endoscopic Submucosal Dissection with Systematically mediastinal Lymph Node Dissection, Endoscopic Submucosal Dissection without SLND
- Volunteers
- 102 people
- Sponsor
- Fujian Cancer Hospital
Early Gastric Cancer or Gastric Adenoma
Full-time RDI for ESD: Impact on Major Adverse Events and Procedure Time
Gastric cancer remains a major global health burden, ranking fifth in incidence worldwide and disproportionately affecting Asia, with China accounting for a significant share of cases and deaths.
- Trial name
- NCT07401303
- Testing
- ESD
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Xijing Hospital of Digestive Diseases