Clinical trials: Substance Use Recovery
Alcohol Use Disorder, Alcohol Use, Unspecified
Drinking, Acetate, and Stress
The purpose of this study is to learn how drinking alcohol affects how people experience stress and how that is affected by the body's chemistry.
- Conditions
- Alcohol Use Disorder, Alcohol Use, Unspecified, Heavy Drinker, Alcohol Use Disorder, Moderate, in Sustained Remission
- Trial name
- NCT06584448
- Testing
- Deuterium Metabolic Imaging with deuterated acetate tracer
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use Disorder, Opioid Use Disorder
Testing the CrOss Systems Technical Assistance for Retaining Staff (COSTARS) Model for Improving Staff Retention Among Child Welfare Workers and Peer Supporters, and Implementation of Evidence Based Interventions.
The goal of this study is to test whether the CrOss System Technical Assistance for Retaining Staff (COSTARS) supervision leadership institute can promote workforce stability and improved implementation outcomes within the Ohio…
- Conditions
- Substance Use Disorder, Opioid Use Disorder, Child Maltreatment, Implementation
- Trial name
- COSTARS (NCT07439783)
- Testing
- COSTARS, Implementation As Usual
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Alicia Bunger
Substance Use Disorders (SUDs)
Enhancing Delivery of Parenting Support Within a Peer Recovery Support Service Model
The goal of this clinical trial is to evaluate the effectiveness and implementation of Relational Health Enhanced Parenting Support (RHEP), an implementation strategy designed to improve delivery of evidence-based parenting…
- Trial name
- NCT07743359
- Testing
- Relational Health Enhanced Parenting Support (RHEP) implementation bundle, First Steps Together
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Opioid Use Disorder, Peer Recovery Supporters
Peer Recovery Support for Opioid Use Disorder Treatment Retention
The goal of this clinical trial is to learn whether adding peer recovery support services to standard opioid use disorder (OUD) treatment in primary care helps patients stay in treatment longer.
- Conditions
- Opioid Use Disorder, Peer Recovery Supporters, Peer Recovery Coaching, Primary Care
- Trial name
- NCT07620171
- Testing
- Peer Support
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Substance Use Disorders
Smartphone Addiction Recovery Coach for Young Adults (SARC-YA) Experiment
At discharge from outpatient treatment, researchers will recruit 300 young adults and randomly assign them to recovery support as usual control condition or the Smartphone Addiction Recovery Coach for Young Adults (SARC-YA)…
- Trial name
- SARC-YA (NCT03301012)
- Testing
- Recovery support as usual, Smartphone assisted relapse prevention
- Where
- 2 sites in United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Substance Use Disorders, Insomnia
Feasibility of Brief Behavioral Therapy for Insomnia (BBTI) in SUD Recovery
The goal of this clinical study is to learn whether treating sleep problems is helpful in people with substance abuse problems who are living in a residential treatment program.
- Trial name
- BBTI_SUDs (NCT05935735)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Substance Use
Mobile Support to Improve Recovery and Treatment Court Outcomes
This study will fully develop and implement an interactive text messaging intervention system for individuals sentenced to DTC. Upon completion of programming and testing of messages the investigators will enroll 40 participants…
- Trial name
- NCT03668444
- Testing
- TXS- Supportive Text Group, TAU- Treatment As Usual
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Live Inspired, LLC
Opioid-use Disorder
CBT4CBT-Buprenorphine + Recovery Coach for Office-based Buprenorphine
To conduct an 8-week pilot, randomized trial evaluating the feasibility, acceptability, and efficacy of an integrated intervention involving CBT4CBT-Buprenorphine + Recovery Coach in a population of 60 individuals who meet…
- Trial name
- NCT04824404
- Testing
- CBT4CBT-Buprenorphine + Recovery Coach
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Smoking Cessation
Interventions for Smoking Among Persons in Recovery
Examine the efficacy of a stepped-care smoking cessation intervention for current and former smokers in chemical dependency treatment programs.
- Trial name
- INSPIRE (NCT00714896)
- Testing
- Stepped-Care, Control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Opioid Use Disorder, Sleep
The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)
Opioid use disorder (OUD) is a chronic relapsing disorder and is well-known for its high-risk rate of overdoses and death. In OUD, sleep and circadian disruptions are highly prevalent, interfere with opioid maintenance treatment…
- Conditions
- Opioid Use Disorder, Sleep, Circadian Rhythms, fMRI Research
- Trial name
- NCT06832007
- Testing
- AYO light glasses (experimental), AYO light glasses (comparator)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Substance Use Disorder (SUD), mHealth
Connecting Loved Ones to Support and Empowering Recovery
Substance use disorders are highly prevalent. However, recovery from them is possible. The recovery process can benefit greatly from support from loved ones.
- Trial name
- Project Closer (NCT07740395)
- Testing
- KulaMind-Recovery
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Substance Use
Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches & Across INcarceration Settings
The goal of this study is to learn whether a virtual peer recovery coach (PRC) intervention can improve engagement in addiction treatment among incarcerated adults with substance use disorders.
- Trial name
- LINCS UP & IN (NCT07563517)
- Testing
- Virtual Peer Recovery Coaching, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Emory University
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Substance Use Disorders, Overdose
Emergency Medicine Peer Outreach Worker Engagement for Recovery
This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist program (PCHW), the Substance Misuse Assistance Response Team (SMART).
- Conditions
- Substance Use Disorders, Overdose, Opioid Use Disorder, Alcohol Use Disorder
- Trial name
- EMPOWER (NCT06320015)
- Testing
- Substance Misuse Assistance Response Team (SMART), Usual Care Group
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Substance Use, Mental Health Issue
Community Driven Substance Use Recovery for High Opioid Overdose Areas
The main goal of this current study is to develop and optimize methods for increasing access to, uptake of, and engagement in MAT (Medication Assisted Treatment) among communities of color.
- Conditions
- Substance Use, Mental Health Issue, Opioid Use, Medication Assisted Treatment
- Trial name
- IMANI U (NCT05260047)
- Testing
- IMANI, Telehealth MAT, Traditional MAT plus Referral and Linkage
- Where
- 8 sites in United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use
Developing SUPPORT, a Community-Driven, Recovery-Oriented System of Care
The investigators seek to develop and assess the effectiveness of Substance Use Programming for Person-Oriented Recovery and Treatment (SUPPORT), a community-driven recovery-oriented system of care for individuals recently…
- Trial name
- SUPPORT (NCT03132753)
- Testing
- SUPPORT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Behavior, Health
Peer-Delivered Episodic Future Thinking for Returning Citizens
The goal of this study is to examine the effectiveness of a brief, episodic future thinking (EFT) intervention in a substance use treatment setting serving returning citizens with substance use disorders (SUD).
- Trial name
- NCT06119503
- Testing
- Elongating Time HOrizons for Reentry (ETHoR), Standardized Episodic Thinking (SET)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcohol Use Disorder (AUD), Alcohol Abstinence
SER-ABS-AUD: Neuropsychosocial-Spiritual Correlates of Serene Abstinence in Adults With AUD
SER-ABS-AUD is a single-centre, non-interventional, mixed retrospective-prospective longitudinal cohort study of 70 adults aged 18-70 years with documented alcohol use disorder, at least 12 consecutive months of continuous…
- Trial name
- SER-ABS-AUD (NCT07561749)
- Where
- Romania
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Support Persons, Family Members
Recovery Inspired Support Engagement (RISE) Pilot
The goal of this clinical trial is to learn if a 1-on-1 support program is easy to complete and acceptable for people supporting loved ones who have recently received treatment for substance use.
- Conditions
- Support Persons, Family Members, Chosen Family, Romantic Partners
- Trial name
- (RISE) (NCT07519759)
- Testing
- ITC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital