Clinical trials: Suffering
Schizophrenia
A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia
A Clinical Study that will look at an investigational medication, SEP-363856 (called "study medication") in patients with schizophrenia, and assess wether it affectsbody-weight associated parameters.
- Trial name
- NCT05542264
- Testing
- SEP-363856, Prior antipsychotic (risperidone, olanzapine, quetiapine or aripiprazole)
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Parkinson Disease Psychosis
Hallucinations in Parkinson's Disease
Investigation on how robotically mediated sensorimotor stimulation induces and triggers presence hallucinations in different clinical groups of parkinsonian patients, and in aged-matched controls
- Trial name
- NCT04592965
- Testing
- Clinical and neuropsychological assessments, Induction of PH and associated bodily states, Resting-state fMRI acquisition
- Where
- 6 sites in Spain, Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Olaf Blanke
Cataract, Diabetes Mellitus Type 2
Role of Metformin in Posterior Capsule Opacification
Determination of concentrations of systemically applied metformin in human lens capsule and its ability to lower the proliferation rate of human lens epithelial cells in vitro.
- Trial name
- NCT07176338
- Testing
- Blood and lens capsule samples for PK testing
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
COPD
Has Pulmonary Rehabilitation a Positive Impact on Sleep Quality in Patients Suffering From COPD ?
The purpose of our study is to assess the impact of pulmonary rehabilitation on objective sleep quality in COPD patients.
- Trial name
- NCT03314558
- Testing
- pulmonary rehabilitation
- Where
- Belgium
- Volunteers
- 31 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Acid Peptic Disorder
Effect of Digene Total (Buffered Pantoprazole) on 24 Hour Gastric Potential Hydrogen (pH) in Patients From Acid Peptic Disorder After Single and Repeated Dosing.
This prospective, open label, single-center and non-comparative study is designed to generate data on Digene Total's (buffered pantoprazole) rapid and sustained gastric acid inhibition effect in patients suffering from acid…
- Trial name
- NCT01214408
- Testing
- Buffered pantoprazole
- Where
- India
- Volunteers
- 47 people
- Sponsor
- Abbott
Pulmonary Hypertension, Pulmonary Hypertension Chronic Thromboembolic
Medication Reconciliation in Pulmonary Hypertension
Pulmonary hypertension (PH) is a life threatening condition. In PH, pulmonary arterial hypertension (PAH) and chronic thrombo-embolic chronic pulmonary hypertension (CTEPH) are two rare diseases requiring specific and complex…
- Conditions
- Pulmonary Hypertension, Pulmonary Hypertension Chronic Thromboembolic, Pulmonary Arterial Hypertension
- Trial name
- OPTICARE-HTP (NCT04744584)
- Testing
- Medication reconciliation
- Where
- France
- Volunteers
- 129 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fourth Cranial Nerve Palsy
Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.
- Trial name
- IVPareseZahn (NCT02149355)
- Testing
- teeth molding
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sciatica, Lumbosacral Radiculopathy
Three CT Signs of Nerve-root Suffering in Low-back Sciatica: a Study of Their Frequency in Patients Referred for CT-guided Nerve-root Infiltration.
Retrospective, observational, single-centre study conducted at Nice University Hospital (Pasteur 2), Department of Diagnostic and Interventional Radiology.
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Low Back Pain
- Trial name
- NCT07690449
- Testing
- Pre-infiltration lumbar planning CT scan - reading of the three nerve-root signs
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Back Pain Lower Back Chronic
The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination
To determine the effects of pregabalin in reducing pain intensity and improving functional disability in patients with chronic low back pain of neuropathic origin when used in combination with Etoricoxib.
- Trial name
- NCT06401499
- Testing
- etoricoxib 60mg
- Volunteers
- 140 people
- Sponsor
- Muhammad Ilyas
Type 1 Diabetes, Obesity
Prevalence of Overweight and Obesity in Adult Patients Suffering From Type 1 Diabetes
A registry of individuals with type 1 diabetes that visited the Department of Endocrinology of the University Hospitals of Leuven is established.
- Trial name
- POOT1 (NCT05713448)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 100,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spinal Cord Stimulation (SCS), Chronic Pain
Psychological Assessment in Patients Treated with Spinal Cord Stimulation
This is a prospective observational study to investigate the impact of spinal cord stimulation (SCS) procedure in chronic pain perception and management.
- Trial name
- NCT06761300
- Testing
- Psychological assessment
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- European Institute of Oncology
Vaginal Microbiome
Influence of Probiotics on the Vaginal Microbiota
The study aims to assess the influence of a probiotic supplement (OMNi-BiOTiC® FLORA plus +) on the vaginal microbiome composition of women suffering from infertility.
- Trial name
- NCT04471116
- Testing
- OMNi-BiOTiC® FLORA plus+
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Kinderwunsch Institut GmbH
Appendicitis, Yersinia Enterocolitica Infection
Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies
Trial The aim of the study is to investigate which infectious diseases might mimic the symptoms of acute appendicitis to a degree to cause a diagnostic laparoscopy or laparoscopic appendectomy.
- Conditions
- Appendicitis, Yersinia Enterocolitica Infection, Yersinia Pseudotuberculosis Infections, Appendectomy
- Trial name
- NCT03349814
- Testing
- Diagnostic laparoscopy without appendectomy, Diagnostic laparoscopy with appendectomy
- Where
- Denmark
- Volunteers
- 225 people
- Sponsor
- Herlev Hospital
Axial Spondyloarthritis
Video Coaching of Physical Activity in Axial Spondyloarthritis
The primary objective of the study is to demonstrate the beneficial effect of a 3 months home-based physical exercise program supervised by online videos, in addition to the usual recommendations, in comparison with usual…
- Trial name
- SatiSpAction (NCT03965650)
- Testing
- Video coaching exercises, Routine exercises
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Crohn's Disease
Mucosal Healing Study in Crohn's Disease (CD)
The aim of the study will be to investigate the effect of certolizumab pegol on the intestinal mucosa in active Crohn's disease.
- Trial name
- MUSIC (NCT00297648)
- Testing
- Certolizumab pegol
- Where
- 19 sites in Belgium, France and 1 more
- Volunteers
- 89 people
- Sponsor
- UCB Pharma
Functional Gastrointestinal Disorders
Study to Learn More About the Stomach and Intestine Complaints of Children Aged From 3 to 14 Years
In this observational study, researchers want to gain more information on children suffering from abnormal stomach and intestine function (based on the Rome criteria) and treated Iberogast.
- Trial name
- NCT04029376
- Testing
- Iberogast®
- Where
- Germany
- Volunteers
- 1,032 people
- Sponsor
- Bayer
Obesity
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects…
- Trial name
- NCT05064735
- Testing
- semaglutide 2.4 mg
- Where
- 122 sites in United States, Canada and 9 more
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Stress Disorder, Combat
Benefits of Diving Training on Recovery for Veterans Suffering of Chronic PTSD: an Exploratory Study
Patients suffering from Chronic Posttraumatic Stress Disorder (PTSD) have difficulties in executive cognition that hinder their quality of life and make it difficult to recovery and to reintegrate them socially and…
- Trial name
- cognidive (NCT03995992)
- Testing
- sport
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Institut de Recherche Biomedicale des Armees
Acute Myocardial Infarction, Pain
To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services
This is an intervention study focusing on both medical and nursing questions. The study is a joint project between the Ambulance services at four cities in West Sweden and Knowledge and research centre, PreHospen at University of…
- Trial name
- NCT00792181
- Testing
- Midazolam, Course intervention - a professional development course for caregivers.
- Volunteers
- 2,800 people
- Sponsor
- Sahlgrenska University Hospital
Melanoma
Safety and Efficacy of Intramuscular Electrotransfer of Plasmid AMEP in Patients Suffering From Advanced or Metastatic Melanoma
The objective of the present trial is: to determine the dose limiting toxicity (DLT), maximal tolerated dose (MTD) and recommended phase 2 dose (RP2D) of intramuscular electrotransferred Plasmid AMEP in patients with advanced or…
- Trial name
- AIMM (NCT01764009)
- Testing
- naked DNA coding for protein AMEP
- Where
- 4 sites in France, Slovenia
- Sponsor
- Valerio Therapeutics
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