Clinical trials: Suicidal Behavior, open to volunteers
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide, Attempted
iTBS+D-Cycloserine for Youth Suicide
Background and Rationale: Suicide is the second leading cause of death in Canadian Emerging Adults (EAs; 18-24yrs). Current treatments for suicidal thoughts and behaviors are limited and novel treatments are required to save…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Depression, Anxiety
- Trial name
- NCT06121284
- Testing
- D-Cycloserine, intermittent Theta-Burst-repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Inhibitory Control, Locus of Control
Neuropsychological Patterns of Suicide Ideators and Suicide Attempters
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
- Conditions
- Inhibitory Control, Locus of Control, Self Efficacy, Suicide, Attempted
- Trial name
- NePsyAssip HT (NCT06248268)
- Testing
- (Neuro-)psychological assessment
- Where
- Switzerland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Bern
Suicide Prevention, Suicidal Ideation
Online Suicide Prevention and Intervention Training for Secondary School Counselors
The aim of this study is to develop and evaluate the effectiveness of the Online Suicide Prevention and Intervention Training Program (Çevrimiçi İntihar Önleme ve Müdahale Eğitim Programı - ÇİÖMEP) for school counselors working…
- Conditions
- Suicide Prevention, Suicidal Ideation, School Counseling
- Trial name
- NCT07432438
- Testing
- Online Suicide Prevention and Intervention Training Program (ÇİÖMEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Suicide Risk, Suicide Attempt
Study to Refine the Effectiveness of New Generation Therapies for Suicide
The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.
- Conditions
- Suicide Risk, Suicide Attempt, Treatment Response
- Trial name
- STRENGTHENS (NCT07818889)
- Testing
- Brief Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Suicidal Behavior, Adolescent
Suicidal Behavior in Adolescents and Executive Functions
Suicide is a major public health concern, particularly among young people. In France, around 400 adolescents die by suicide every year, and suicide attempts are most frequent during adolescence.
- Trial name
- SAFE (NCT07422493)
- Testing
- Neuropsychological Tests and Psychiatric Tests
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Suicide
Mobile Intervention for Suicidal Thoughts
One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel.
- Trial name
- NCT06593379
- Testing
- Safety planning, Treatment as usual, MIST Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Suicide
Testing the Efficacy of ACT for Life
Psychiatric hospitalization is a critical opportunity to provide treatment to reduce the risk of suicide and lay the groundwork for functional recovery.
- Trial name
- NCT04829682
- Testing
- ACT for Life, Present Centered Therapy
- Where
- 2 sites in United States
- Volunteers
- 278 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicidal Behaviors
Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study
The goal of this study is to finalize a version of the Safety Planning Intervention suitable for 6-12-year-old children. This intervention provides individuals with strategies to reduce the risk of suicidal behavior.
- Trial name
- NCT07564583
- Testing
- Child - Safety Planning Intervention, C-SPI+ecological momentary assessment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Columbia University
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
The purpose of this research is to see if Crisis Response Planning (CRP), a brief strategy designed to help people cope effectively with emotional crises, combined with Cognitive Processing Therapy (CPT), a talk treatment for…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
- Trial name
- mCPT+CRP (NCT07238192)
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Ohio State University
Suicidal Ideation
WeCare: A System of Care for Black Youth
The overall goal of this study is to respond to the urgent need for an effective suicide prevention strategy for Black youth by examining the effectiveness of a systems-level strategy to recognize and respond to suicide risk…
- Trial name
- WeCare (NCT05654207)
- Testing
- WeCare
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- New York University
Prevention of Suicidal Behavior
Impact of a High-resolution Program for the Prevention of Suicidal Behavior in At-risk Adults: a Quasi-experimental Ambispective Cohort Study
Background: Suicidal behavior represents a major public health problem worldwide. According to the World Health Organization (WHO), approximately 720.000 people die by suicide annually, and many more attempt it.
- Trial name
- NCT07655986
- Testing
- PPS; SUICIDE PREVENTION PROGRAM
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- University of Salamanca
Depressive Disorder, Major Depressive Disorder
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
The purpose of this study is to test the hypothesis that the anti-depressant and anti-suicidal effects of the N-methyl-D-aspartate receptor (NMDAR) antagonist Ketamine is critically dependent on stimulation of…
- Conditions
- Depressive Disorder, Major Depressive Disorder, Bipolar Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT05786066
- Testing
- Perampanel 6 MG, Ketamine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Adolescent Suicide, Suicidal Ideation
Shame-Focused Cognitive Behavioral Therapy For Reducing Suicide Risk In Adolescent Psychiatric Inpatients (SF-CBT)
This pilot randomized controlled trial (RCT) aims to evaluate the feasibility, acceptability, and preliminary efficacy of Shame-Focused Cognitive Behavioral Therapy (SF-CBT) among high-risk psychiatric inpatient adolescents.
- Conditions
- Adolescent Suicide, Suicidal Ideation, Suicidal Behavior, Shame
- Trial name
- SF-CBT (NCT07294001)
- Testing
- Supportive Therapy (ST)
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Peking University
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Suicide
A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents
Suicide risk has increased among youth in underserved communities, where access to mental healthcare is limited. To address this need, the investigator team plans to evaluate the preliminary efficacy of a brief, low-cost…
- Trial name
- SWEEP (NCT06349915)
- Testing
- Supporting Wellbeing with Everyday Experiences of Peers (SWEEP)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Albert Einstein College of Medicine
Major Depressive Disorder, Depression
Nitrous Oxide- Suicidal Ideation
Most clinical major depression responds to standard treatments (medication and psychotherapy); however, a significant subset of depressed patients (15-20%) do not respond to these treatments and are referred to as…
- Conditions
- Major Depressive Disorder, Depression, Mood Disorders, Suicidal Ideation
- Trial name
- NCT03736538
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Suicidal Thoughts and Behaviors
Standardized Adaptive Music Medicine for Suicidality
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors.
- Trial name
- STAMM-S (NCT07610785)
- Testing
- STAMM-S
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Major Depressive Disorder, Suicide
Accelerated iTBS for Depression and Suicidality
The overall objective of this current study is to evaluate the feasibility, safety, and tolerability of "high dose" aiTBS in psychiatric inpatient and outpatients with treatment-refractory unipolar, non-psychotic major depressive…
- Trial name
- RAPID (NCT04441008)
- Testing
- Accelerated Intermittent Theta Burst (aiTBS), Electroconvulsive therapy (ECT)
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester