Clinical trials: Suicidal Behaviour
Anxiety, Mental Health
CONSCIOUS: A Pilot Trial of a Media Orientation Intervention to Encourage Men's Help Seeking for Mental Health Difficulties
Mental health difficulties among males are an issue of public health concern. Men are also at higher risk of suicidal ideation and self-harm and are poor at help-seeking due to factors including stigma, cultural norms and…
- Conditions
- Anxiety, Mental Health, Suicide Awareness, Awareness Training
- Trial name
- CONSCIOUS (NCT07627451)
- Testing
- Psychosocial media campaign, Intervention as usual
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Teesside University
Healthy
Electrophysiological Biomarkers of AV-101
Suicide is 2-7x higher in Veterans than non-veterans, and may be related to brain kynurenine pathway (KP) dysregulation and NMDA receptor (NMDAR) hyperactivation.
- Trial name
- NCT03583554
- Testing
- AV-101 720 mg, AV-101 1440 mg
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Marijn Lijffijt, PhD
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Suicidal Ideation
Improving Our Understanding of Suicidal Ideation in Cancer Survivors
The goal of this project is to assess the feasibility of collecting physiological and psychological data that will allow for preliminary investigation of predictors of suicidal ideation in an ambulatory cancer population already…
- Trial name
- NCT04866758
- Testing
- Survey
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Affect, Wellness, Psychological
The Effects of Walking in Nature (vs. an Urban Setting) on the Wellbeing of Postsecondary Students.
The goal of this randomized controlled trial is to examine the effects of a walking intervention (3 walks per week for a period of 4 weeks) in a nature vs. urban setting on the wellbeing of young adult postsecondary students.
- Conditions
- Affect, Wellness, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05889078
- Testing
- A 4-week walking intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McGill University
Reintegration Difficulties, Health
National Sponsorship Program for Transitioning Service Members
Background: The United States is undergoing a suicide epidemic for its youngest Veterans (18-to-34-years-old) as their suicide rate has almost doubled since 2001.
- Conditions
- Reintegration Difficulties, Health, Suicidal Ideation and Behaviors, Connectedness
- Trial name
- NCT05224440
- Testing
- Veteran Sponsorship Initiative
- Where
- 2 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder, Suicide
Identifying the Neural Basis of Capability for Suicide
Since capability for suicide involves overriding potential pain, and the opioid system plays a strong role in controlling pain perception, it follows that capability for suicide may be impacted by the opioid system.
- Conditions
- Major Depressive Disorder, Suicide, Suicidal Ideation, Psychiatric Illness
- Trial name
- NCT03327129
- Testing
- fMRI
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Non-suicidal Self-injury
Treatment for Non-Suicidal Self-Injury in Young Adults
The purpose of this study is to investigate an intervention specifically for non-suicidal self-injury (NSSI) in young adults. The goal of this 9-session outpatient intervention is to reduce the frequency and severity of NSSI.
- Trial name
- T-SIB (NCT01018433)
- Testing
- T-SIB, Treatment as usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fordham University
Depression, Anxiety
Pilot Test of a Cultural Intervention to Enhance Alaska Native Students' Behavioral Health
This project aims to enhance AN university students' behavioral health by supporting their cultural identity development. While the connection between cultural identity and behavioral health is becoming clearer, comparably less…
- Conditions
- Depression, Anxiety, Suicidal Ideation, Substance Use
- Trial name
- NCT04561544
- Testing
- Knowing Who You Are (Becoming): Cultural Identity Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alaska Anchorage
Suicide, Attempted, Mood Disorder
Functional Imaging of Psychic Pain
Suicidal behaviour (SB) represents a major public health problem, costing life in more that one million people every year worldwide.
- Trial name
- NCT01493323
- Testing
- Assessment of personality traits, Assessment of suicidal act, Assessment of depression
- Where
- France
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Suicide, Nurse's Role
Nurse Suicide: Physiologic Sleep Health Promotion Trial
The purpose of this study is to identify factors (sleep, psychiatric characteristics, stressful life events, and work environment characteristics) that potentiate or mitigate adverse effects of real-world stressors that…
- Conditions
- Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep
- Trial name
- NCT06079853
- Testing
- PureSomni Sleep Health Product Kit
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Columbia University
Tobacco Dependence, Suicidal
DBT for Smoking Cessation in High Risk Veterans
Individuals prone to suicidality are typically excluded from tobacco cessation interventions even though they are disproportionately likely to smoke, and even though smoking cessation has been linked to improved mood and reduced…
- Trial name
- NCT06687577
- Testing
- DBT-C, Treatment as usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Veterans Medical Research Foundation
Suicidal Ideation
Evaluation of Creative Materials Supporting Healthcare Professionals in Discussing Suicidality in Children and Adolescents
Preliminary research clearly indicates a significant shortage of evidence-based tools and interventions specifically targeting suicidality among children and adolescents.
- Trial name
- NCT07043231
- Testing
- Creative materials
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide, Attempted, Suicidal Ideation
Biomarkers as Predictors of Suicidal Risk in Adolescents
Suicide is one of the most devastating events in society at all levels. The primary goal of this study is to predict suicide in adolescents at risk.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Suicidal Intention, Suicide
- Trial name
- NCT03014518
- Testing
- Clinical assessments and blood samples; follow-up for 12 mos, Clinical assessments and blood samples; no 12mo follow-up
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Suicide
Research on Suicidal Ideation of University Students in Harbin City and Cognitive Behavior Therapy
The purposes of this research are: to understand the status of suicidal ideation, suicidal behavior, and depression in Harbin University students; and to analyse the infect factors of suicidal ideation and suicidal behavior.
- Trial name
- NCT00575575
- Testing
- cognitive behavior therapy
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Suicidal Ideation
WeCare: A System of Care for Black Youth
The overall goal of this study is to respond to the urgent need for an effective suicide prevention strategy for Black youth by examining the effectiveness of a systems-level strategy to recognize and respond to suicide risk…
- Trial name
- WeCare (NCT05654207)
- Testing
- WeCare
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- New York University
Suicide Prevention, Suicide
Co-creation of Tools for People in Detention With Suicidal Thoughts and/or Behavior
People in detention are at significantly higher risk of suicide compared to the general population. In Belgian prisons, the suicide rate is five times higher than average.
- Conditions
- Suicide Prevention, Suicide, Suicidal Ideation
- Trial name
- NCT07259408
- Testing
- Co-creation process for suicide prevention tools in detention
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Self-Harm, Deliberate, Suicidal Ideation
Testing the Competency-based Theory of Change for Suicide Risk Among Young Male Internet Users With Societal Masculinity
To propose a competency-based theory of change for reducing suicide risks among male Internet users with salient traits of societal masculinity; To test whether the theory of change using the competency-based model has additional…
- Conditions
- Self-Harm, Deliberate, Suicidal Ideation, Masculinity
- Trial name
- NCT04591223
- Testing
- Competency-based physical training (CbM)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Substance Abuse, Suicide
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents.
- Conditions
- Substance Abuse, Suicide, Depression
- Trial name
- NCT05489042
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Depression, Anxiety
Perinatal Mental Health Study (PMHS) India
The purpose of this observational study is to improve understanding of mental disorders among perinatal women in India.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Somatization
- Trial name
- PMHS (NCT05485701)
- Testing
- Screening tools for common mental disorders
- Where
- 2 sites in India
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- University of Oxford