Clinical trials: Suicidal Ideation/Behavior
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicidal Ideation, Suicide, Attempted
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Coping Skills, Depression
- Trial name
- ProjectGRRIT (NCT05401838)
- Testing
- Group Brief Cognitive-Behavioral Therapy (G-BCBT), Dialectical Behavior Therapy (DBT) Skills Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- University of North Carolina, Charlotte
Suicidal Ideation, Suicide Attempt
Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial
This study outlines a randomized controlled trial evaluating two brief suicide-specific interventions for adolescents aged 12-17 who are hospitalized for suicidal ideation or attempts.
- Conditions
- Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder
- Trial name
- NCT07628192
- Testing
- CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The Cleveland Clinic
Self-harm, Suicidal Ideation
CaMaPi for Adolescents/Young People With a History of Self-harm and Suicidal Ideation in Jos, Nigeria
Suicide and self-harm are global disease burden that contributes significantly to years of lost life and mortality.
- Trial name
- CaMaPi (NCT06440031)
- Testing
- CaMaPi, TAU
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Adolescent Behavior
Brief Intervention for Suicide Risk Reduction in High Risk Adolescents
Adolescent suicide is the 2nd leading cause of death in this age group. There are no validated treatments to decrease the risk of adolescent suicidal behavior, and there are especially no interventions to target the highest risk…
- Trial name
- ASAP (NCT02272179)
- Testing
- As Safe As Possible, Brite, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Pittsburgh
Suicidal Thoughts and Behaviors, Social Connectedness
Social Threat, Adolescent Relationships, and Suicidality Study
In recent years, adolescents are having higher rates of emotional health problems, such as suicidal thoughts and behaviors (STBs).
- Conditions
- Suicidal Thoughts and Behaviors, Social Connectedness, Responses to Social Threat
- Trial name
- STARS (NCT07294079)
- Testing
- Social threat
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicidal Ideation, Suicide Attempt
Teen Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- Teen RISE (NCT07170657)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicidal Ideation
Ketamine For Suicidal Ideation
This study will examine the effects of Intravenous (IV) ketamine both in an outpatient population and with subjects on the inpatient unit with suicidal ideation (SI).
- Trial name
- NCT01507181
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- James Murrough
Suicidal Ideation
Stratified-Care School-Based Intervention for Adolescent Suicidal Ideation
Background. Suicidal ideation and depressive symptoms are highly prevalent among adolescents, with suicide representing a leading cause of death in this age group worldwide.
- Trial name
- NCT07063914
- Testing
- Reframe-IT and CARIBOU
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de los Andes, Chile
Depression Disorders, Suicidality
Effectiveness of the Adapt for Life, Mental Wellness and Suicide Prevention Program
Adapt for Life is a mental health and wellbeing program designed to help young people develop healthy behaviors and important life skills to manage stress and mental health challenges.
- Trial name
- AFL (NCT06979479)
- Testing
- school-based intervention
- Where
- United States
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mood Disorders, Suicidal Ideation
Esketamine vs ECT for Acute Suicidality
This study is a multicenter, randomized, non-inferiority, parallel-group clinical trial designed to evaluate the efficacy and safety of esketamine compared with electroconvulsive therapy (ECT) in the treatment of suicidal…
- Conditions
- Mood Disorders, Suicidal Ideation, Depressive Episode
- Trial name
- NCT06355180
- Testing
- Esketamine, Electroconvulsive therapy
- Where
- 6 sites in China
- Volunteers
- 340 people
- Sponsor
- Capital Medical University
Suicidal Ideation
Home-based tDCS for Prevention of Suicidal Ideation
Risk for suicide is elevated in the period after discharge from hospital among adults with major affective disorder. The primary objective of this study is to investigate the feasibility of delivering tDCS sessions for high-risk…
- Trial name
- NCT05280756
- Testing
- Home-based transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Rochester
Suicide, Suicidal Ideation
Intensive Crisis Intervention
The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm
- Trial name
- ICI (NCT06476886)
- Testing
- Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Jennifer Hughes
Suicidal Ideation, Suicide Attempt
Expansion and Reevaluation of the Implicit Association Test in Suicide Ideators and Suicide Attempters
A new approach to investigate suicidal processes belongs to the broader neurocognitive picture and are so-called implicit associations.
- Trial name
- IAT-S (NCT04585802)
- Where
- Switzerland
- Volunteers
- 447 people
- Sponsor
- University of Bern
Depression, Depressive Disorder
Reward Processing and Depressive Subtypes: Identifying Neural Biotypes
Deficits in motivation and pleasure are common in depression, and thought to be caused by alterations in the ways in which the brain anticipates, evaluates, and adaptively uses reward-related information.
- Conditions
- Depression, Depressive Disorder, Major Depressive Disorder, Major Depressive Episode
- Trial name
- NCT06080646
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Nightmare
Cognitive-Behavioral Therapy for Children With Nightmares as a Mediator of Suicide Risk (COMAA)
Youth suicide risk has increased 56% in the last decade, and suicide is the leading cause of preventable death in children and adolescents.
- Trial name
- COMAA (NCT05588739)
- Testing
- Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Oklahoma
Psychological Distress, Anxiety
Feasibility and Acceptability of PRISMA for Prisoners in Switzerland
In response to the significant mental health challenges faced by pretrial detainees, the Swiss Federal Justice Department has initiated a model trial in pretrial detention centres in Zurich and Bern.
- Conditions
- Psychological Distress, Anxiety, Depression, Suicidal Ideation
- Trial name
- NCT06404502
- Testing
- PRISMA
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich