Clinical trials: Suicide and Self Harm
Depression and Suicide Ideation
Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression
The goal of this feasibility study is to develop a new metaverse-based blended online intervention using an online program and coaching via metaverse to prevent depression among Generation MZ Employees in South Korea.
- Trial name
- NCT06426342
- Testing
- metaverse-based blended online intervention
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Chronic Pain, Suicidal Ideation
Mindfulness for Pain and Suicide
The proposed study will assess the feasibility and acceptability of a mindfulness-based intervention to reduce functional impairment from chronic pain and risk of suicide.
- Conditions
- Chronic Pain, Suicidal Ideation, Suicide, Attempted, Opioid Use
- Trial name
- NCT05286112
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Health Education
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Canandaigua VA Medical Center
Suicide, Depression
Plasma Beta-endorphin Levels and Suicidal Behavior
It is an interventional research, monocentric, which involves only minimal risks and constraints. Psychological pain is closely associated with suicidal ideation (SI) and suicidal behavior, regardless of the severity of the…
- Conditions
- Suicide, Depression, Beta Endorphin
- Trial name
- BEST (NCT06291467)
- Testing
- Blood samples, questionnaires
- Where
- France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Montpellier
Suicide, Suicide Ideation
From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk
Financial hardship is an important risk factor for suicide. However, there are no evidence-based interventions to help individuals at risk for suicide to improve their financial situation.
- Conditions
- Suicide, Suicide Ideation, Suicidal Behavior, Hope
- Trial name
- NCT04840134
- Testing
- From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- New York State Psychiatric Institute
Suicide, Attempted, Suicidal Ideation
Assessing the Effectiveness of Self- and Clinician-administered Crisis Response Planning for Suicide Risk
The aim of the current project is to compare the use and preliminary effectiveness of a self-administered version of the Crisis Response Plan (CRP) in decreasing suicidal/death ideation and distress and increasing positive affect…
- Trial name
- NCT04903431
- Testing
- Crisis Response Planning for Suicide Risk
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Suicide and Self-harm
Suicide Prevention for Criminal Legal Involved Managed Care Subscribers
The goal of this clinical trial is to test the effects of a suicide prevention intervention for individuals released from jail. The main question it aims to answer is: Does the use of Caring Contacts improve subscriber engagement…
- Trial name
- NCT05579600
- Testing
- Caring Contacts letters
- Where
- United States
- Volunteers
- 45,155 people
- Sponsor
- Butler Hospital
Suicide, Suicidal Ideation
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED).
- Conditions
- Suicide, Suicidal Ideation, Depression
- Trial name
- NCT06085937
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Lindsay Maguire, MD
Depressive Disorder, Major, Suicidal
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide
The purpose of the study is to evaluate the efficacy, safety, and tolerability of SLS-002 (intranasal racemic ketamine) in addition to standard of care on symptoms of Major Depressive Disorder (MDD) and suicidality, in…
- Trial name
- NCT04669665
- Testing
- SLS-002, Standard of care, Intranasal device
- Where
- 21 sites in United States
- Volunteers
- 164 people
- Sponsor
- Seelos Therapeutics, Inc.
Bipolar Disorder (BD), Suicidality
Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression
Bipolar disorder is characterized by manic episodes and episodes of extreme depressive feelings, also known as bipolar depression (BD).
- Trial name
- DEEPP (NCT05177146)
- Testing
- Intravenous Ketamine (IV)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Centre for Addiction and Mental Health
Depression in Adolescence, Suicide Prevention
Strategic Treatment and Assessment for Youth (STAY)
This multi-method, multi-phase pilot trial is designed to explore initial implementation and effectiveness of a theoretically-driven, culturally-tailored, measurement-based care (MBC) approach, Strategic Treatment Assessment for…
- Trial name
- STAY (NCT06515236)
- Testing
- Strategic Treatment Assessment for Youth (STAY), Measurement Based Care As Usual
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Yale University
Persons With High Suicide Ideation or Attempts
Cognition, Metacognition, and Stigma in Patients With Suicidal Ideation
Deficits of executive function, meta cognition and stigma is known in suicidal ideation; however, their relationship is unknown.
- Trial name
- NCT06652815
- Testing
- Suicide ideation or suicide attempt
- Volunteers
- 212 people
- Sponsor
- University of Pittsburgh
Suicide, Trauma
Integrated Suicide & Trauma Therapy for Suicide Risk
The investigators have developed a novel suicide intervention, Integrated Suicide and Trauma Therapy (ISTT). ISTT combines Brief-Skills for Safer Living (Brief-SfSL)-a promising method to enhance coping skills and reduce…
- Conditions
- Suicide, Trauma, Major Depressive Disorder
- Trial name
- ISTT (NCT05613972)
- Testing
- Integrated Suicide and Trauma Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Suicide, Crisis; Emotional
Study About Group and Phone Follow-Up After a Crisis
Crisis stabilization centers (CSCs) provide a less costly and more comfortable alternative to Emergency Department care for individuals with suicidal crises.
- Trial name
- NCT05637203
- Testing
- THRIVE (Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement), Discharge / Safety Planning
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- University of Rochester
Suicide
Emotional Prosody Recognition and Decision Making Inf fMRI and Vulnerability to Suicide
Suicide is known to be frequent in depression, and in most of the psychiatric diseases. But as it can occur in patients with no psychiatric illness and doesn't occur in every patients with psychiatric illness, it has to be…
- Trial name
- EMODES (NCT02901769)
- Testing
- fMRI
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Suicide
Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)
The overarching goal of this study is to develop a suicide prevention program for sexual-and-gender-minority youth and emerging adults.
- Trial name
- NCT05087966
- Testing
- Safety Planning Intervention with Navigation Services
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Depression, Suicide
Reaching Out to Distressed Medical Residents, Fellows and Faculty
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and…
- Trial name
- NCT02010866
- Testing
- counseling
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Suicide, Alcohol Abuse
Alcohol, Suicide and HIV Prevention for Teens in Mental Health Treatment
This study examines whether an integrated alcohol/substance abuse, suicide, and HIV prevention protocol is associated with lower onset and frequency of alcohol and other drug use, suicidal behavior, and high risk sexual behavior…
- Conditions
- Suicide, Alcohol Abuse, Drug Abuse, HIV
- Trial name
- NCT02228044
- Testing
- Prevention program
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- George Mason University
Suicide Prevention, Nurses
The Effect of the Awareness Development Program on Suicide Prevention for Oncology Nurses
The goal of this clinical trial is to investigate the effect of the Awareness Development Programme on Suicide Prevention for Oncology Nurses on the levels of knowledge, stigma and perception of efficacy towards suicide in…
- Trial name
- RCT (NCT06282263)
- Testing
- "Awareness Development Program on Suicide Prevention for Oncology Nurses"
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Sevda Ozturk
Suicide, Attempted
Randomized Controlled and Prospective Trial of a Cohort of People Who Made a Suicide Attempt
The prevention of recurrent suicidal about people who have made a suicide attempt is a major strand in the prevention of suicide. It is estimated that 10-15 % of people who made a suicide attempt die by suicide.
- Trial name
- OSTA (NCT01176929)
- Testing
- Usual treatment and Prevention program, Usual Treatment
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicidal Thoughts and Behaviors, Major Depressive Episode (MDE)
Biomarker Discovery for Suicide Precision Circuit Therapeutics
This is a prospective observational biomarker study assessing changes in clinical, behavioral, neuroimaging, and neurophysiological measurer following ketamine/esketamine or electroconvulsive therapy (ECT) in adults with suicidal…
- Trial name
- NCT07723066
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital