Clinical trials: Suicide and Self Harm
Child Behavior Disorders, Suicide and Self-harm
iKinnect2.0 for Juvenile Justice Involved Youth at Risk for Suicide
This study is a 16-week intent-to-treat randomized controlled trial (RCT) with 120 suicidal juvenile justice (JJ)-involved transition-age (TA) youth (age 15-21 years) and a primary caregiver (dyads).
- Trial name
- NCT04909203
- Testing
- iKinnect2.0, Active Control App
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Suicide and Depression, Psychological Distress
Preventing Psychological Distress and Suicidal Behaviours: a Web-based and Mobile Suicide Prevention Intervention in the General Population
An interventional research study will be undertaken to assess the effectiveness of the promotion at the local level of an e-health tool for suicide and psychological distress prevention (the StopBlues application and website).
- Conditions
- Suicide and Depression, Psychological Distress, Anxiety Disorders, Local Authorities Promotion
- Trial name
- PRINTEMPS (NCT03565562)
- Testing
- Promotion of the e-health tool by local authorities, Promotion of the e-health tool by local authorities and GPs
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Suicidal Ideation, Suicidal and Self-injurious Behavior
Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
School-based mental health literacy interventions have been shown to reduce and/or prevent suicidal ideation and attempts. Most programs to date include an adapted version of Cognitive Behavioural Therapy (CBT) - the gold…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide Attempt
- Trial name
- NCT04770168
- Testing
- Cognitive Behavioral Therapy Curriculum
- Where
- Canada
- Volunteers
- 3,204 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Major Depressive Disorder, Suicide, Attempted
A Longitudinal Study of Inflammatory Pathways in Depression
Suicide accounts for at least 1 million deaths globally each year. This is likely a significant underestimate, because suicide is under-reported in many countries. In the US, over 42,000 people die from suicide annually.
- Trial name
- NCT04159207
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Van Andel Research Institute
Suicidal Thoughts, Sexual and Gender Minorities
Piloting a Brief, Online Intervention for Suicidality in Sexual and Gender Minority Youth
Sexual and gender minority youth (i.e., LGBTQ+ individuals) are at elevated risk for suicidal thoughts compared to cisgender/heterosexual youth and there is increased demand for programs and treatments tailored to this…
- Conditions
- Suicidal Thoughts, Sexual and Gender Minorities, Youth
- Trial name
- NCT07402265
- Testing
- KindMind
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Western University
Depression, Anxiety
Mental Health First Aid for College Students
Most college students with mental disorders do not receive treatment, and over 80% of those who die by suicide have never made contact with campus mental health services.
- Conditions
- Depression, Anxiety, Suicidal Ideation, Eating Disorders
- Trial name
- NCT02021344
- Testing
- Mental Health First Aid
- Where
- United States
- Volunteers
- 2,543 people
- Sponsor
- University of Michigan
Suicide, Attempted, Suicide and Depression
Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents
This project aims to examine the signal of efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.
- Conditions
- Suicide, Attempted, Suicide and Depression, Suicide Threat
- Trial name
- TASK (NCT04592809)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Suicide
Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)
This randomized controlled trial will take place in up to 15 community health centers across the state of Illinois. Researchers will be studying S.A.F.E.
- Trial name
- NCT06886776
- Testing
- Implementation package (training and facilitation)
- Where
- United States
- Volunteers
- 1,086 people
- Sponsor
- Northwestern University
Major Depressive Disorder
Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide
Depression and suicide are two leading mental health and public health issues in Taiwan. However, until now, the optimal treatment for refractory depression and suicide is still lacking.
- Trial name
- NCT03666390
- Testing
- Ketamine, Midazolam
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Reduction in Mental Health and Suicide Are the Focus of Interest, Four Assessment Time Points Would be Used to Monitor Participants Through a Laid Down Conditions
Cognitive Resilience Intervention as a Recovery Therapy for Mental Health
The goal of this randomized controlled trial (RCT) is to develop and test a cognitive resilience intervention (CRI) among selected students who are having problems with anxiety, depression, and suicidal thoughts (psychological…
- Trial name
- CRI (NCT06123442)
- Testing
- Cognitive Resilience Intervention
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Depression, Suicidal Ideation
Identification of Genetic Markers and Predictors of Antidepressant-induced Suicidality in Youth Depression
The objective of this study is to identification of genetic markers and predictors of antidepressant-induced suicidality in youth depression.
- Trial name
- NCT02428439
- Testing
- bupropion or lamotrigine
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Suicidal Ideation, Suicide Attempt
Teen Recovery Through Inspiration, Support, and Empowerment
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility.
- Conditions
- Suicidal Ideation, Suicide Attempt, Anxiety, Depression Disorders
- Trial name
- Teen RISE (NCT07170657)
- Testing
- Peer Support Services Recovery
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Suicidal Ideation
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care in Texas
The aim of this pilot study is to reduce suicide among sexual and gender diverse youth ages 18-24 years old. This pilot study will compare two brief suicide prevention interventions that have been adapted for use with this…
- Trial name
- NCT05270785
- Testing
- STAT-PC, YST-III
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Suicidal Ideation
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal…
- Trial name
- NCT05217706
- Testing
- Ketamine, normal Saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rady Children's Hospital, San Diego
Suicide Risk
MIN PLAN VS CBT for Suicide Prevention
1. To investigate the effectiveness of Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP) in University students with Suicide Risk 2.
- Trial name
- NCT05095233
- Testing
- Young Adults Culturally Adapted Manual Assisted Psychological Therapy (YA-CMAP), Min Plan Tool
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Syeda AYAT E ZAINAB Ali
Alcohol Drinking, Suicide, Attempted
Brief Alcohol Intervention and mHealth Booster for Suicidal Adolescents
The primary goal of this study is to test the acceptability and feasibility of iASIST (integrated Alcohol and Suicide Intervention for Suicidal Teens), a novel adjunctive intervention for alcohol use and alcohol-related suicidal…
- Conditions
- Alcohol Drinking, Suicide, Attempted, Adolescent Behavior
- Trial name
- NCT03607318
- Testing
- iASIST
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent
Experiences of Brief Admission From the Perspective of Family and Significant Others
As a result of a randomized controlled trial (NCT02985047) BA is continuously offered to persons with self-harm at risk for suicide in Skåne, Sweden.
- Conditions
- Suicidal Ideation, Self Injurious Behavior Without Suicidal Intent, Self-Harm, Deliberate
- Trial name
- NCT04962217
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Region Skane
Suicidal Ideation, Major Depressive Disorder
The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression
Suicide attempts are a serious concern worldwide. Currently, existing drugs take about three weeks to show effect on suicidal thoughts and drives.
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Healthy Participants
- Trial name
- NCT02037503
- Testing
- Ketamine, Saline
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center