Clinical trials: Suicide and Self-harm
Traumatic Brain Injury, Suicidality
Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients
Those with traumatic brain injury (TBI) are at increased risk for suicidal behavior, and suicidality is associated with executive dysfunction.
- Trial name
- NCT01043432
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Suicidal Ideation
Circles of Hope: Group Intervention for Adolescents With Suicidal Symptoms
This pilot study examines the feasibility, acceptability, and preliminary outcomes of a short-term group psychotherapy intervention for adolescents experiencing suicidal symptoms without immediate suicidal intent.
- Trial name
- COH (NCT07818863)
- Testing
- Circles of Hope Group Psychotherapy
- Volunteers
- 40 people
- Sponsor
- University of Haifa
Suicidal Intention, Suicide, Attempted
Discordance in the Evaluation of Suicidal Intent Between Parents and Adolescents in Adolescence and Evolution of the Suicidal Crisis : a Mixed Study
The goal of this mixed-methods study is to describe the association between the level of parent/adolescent discordance in the assessment of the adolescent's level of suicidal intentionality after a suicid attempt and the…
- Conditions
- Suicidal Intention, Suicide, Attempted, Parent-Child Relations
- Trial name
- discord-Ados (NCT06036290)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Clermont-Ferrand
Post Traumatic Stress Disorder, Suicidal Ideation
Integration of PE & Coping Long-Term With Active Suicide Program for PTSD & Suicide Risk in Military Families
The purpose of this study is to develop an innovative, safe, acceptable, feasible, and efficacious integrated CLASP-PE intervention and to Collect pilot data to evaluate the preliminary evidence of the promise of the…
- Trial name
- NCT04284410
- Testing
- CLASP-PE arm
- Sponsor
- The University of Texas Health Science Center, Houston
Substance Use Disorders, Depression
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
The overall aim of this pilot study is to conduct a preliminary trial to evaluate the acceptability and feasibility of adding a transdiagnostic, emotion-focused group intervention (the Unified Protocol, UP) to treatment as usual…
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder
- Trial name
- ARMS UP (NCT03315208)
- Testing
- Unified Protocol (UP), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Depressive Disorder, Major, Generalized Anxiety Disorder
Student Precarity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Major, Generalized Anxiety Disorder, Suicidal Ideation, Loneliness
- Trial name
- PEPSY (NCT07618208)
- Testing
- Questionnaires
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicide and Self-harm
Suicide Classification System
The purpose of this study is to evaluate whether a new standardized language for categorizing suicidal and self-injury related thoughts and behaviors can be readily adopted for use by mental health clinicians.
- Trial name
- NCT01118156
- Testing
- Education
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Suicidal Ideation, Major Depressive Disorder
Adaptation of Dialectical Behavior Therapy Skills-Groups for Individuals With Suicidal Ideation and Depression
Harley and colleagues demonstrated that adding Dialectical Behavior Therapy (DBT) skills-groups and therapist consultation to treatment as usual successfully reduced symptoms of depression.
- Trial name
- NCT01441258
- Testing
- Dialectical Behavior Therapy Skills (DBT-S) Groups, Wait List-Treatment as Usual, No intervention-treatment as usual
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Maurizio Fava, MD
Depression, Suicide and Self-harm
Telehealth Behavioral Activation for Teens
Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, behavioral activation uses psychoeducation and skill-building to…
- Conditions
- Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild
- Trial name
- NCT06273995
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Baylor College of Medicine
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Autism Spectrum Disorder, Regulation, Self
Development of Self-regulation by Dialectial Behavioural Therapy in Adults With Autism
Individuals with autism spectrum disorder (ASD) are at risk to develop more pervasive emotion-dysregulation. In this study experiences of adults with ASD and severe emotion dysregulation with Integrative Dialectical Behaviour…
- Trial name
- DASHBOARD (NCT05502484)
- Testing
- Integrative Dialectical Behavioural Therapy (DBT)
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Suicide Ideation, Suicide Attempts
Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial
The vast majority of suicides occur in low-and middle-income countries (LMICs), and evidence on effective psychotherapeutic interventions to prevent suicide that are culturally adapted to these contexts is limited.
- Trial name
- NCT07574658
- Testing
- Brief Cognitive-Behavioral Therapy (BCBT) for Suicide Prevention, Supportive Therapy
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Suicide
Ottawa Suicide Prevention in Men Pilot Study
To refine a novel intervention using a combination of a smart phone application with best practice psychotherapy for men who have presented to hospital with intentional self-harm.
- Trial name
- OSSUPilot (NCT02718248)
- Testing
- CHESS Mobile Health smart phone application, Problem solving therapy
- Where
- 2 sites in Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Suicide Ideation, Depressed
Supplementing Inpatient Behavioral Activation Group Psychotherapy
This study will evaluate the feasibility, acceptability, and preliminary effectiveness of a behavioral activation intervention designed for adults hospitalized on an inpatient psychiatric unit.
- Trial name
- NCT07611916
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rutgers, The State University of New Jersey
Trauma, PTSD
Posttraumatic Stress Symptoms Among Rescuers at Risk
This cross-sectional, anonymous online survey aims to examine how salient variables influence PTSS, well-being, and suicidal ideation across the following professions of rescue workers: firefighters, ambulance personnel, police…
- Conditions
- Trauma, PTSD, Self Efficacy, Coping Skills
- Trial name
- NCT03842553
- Testing
- No Intervention: anonymous online survey
- Where
- Switzerland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- University of Bern
Mental Disease
Mental Health Reinforcement in Wayapi and Teko Communities in French Guiana : Evaluation of the Impact of a Mediation Based Activity in Municipalities of Camopi and Trois Saut in French Guiana
In French Guiana, Indigenous people experience high levels of psychological distress and higher rates of suicidal behavior than the rest of the population.
- Trial name
- MCS Impact (NCT07808801)
- Where
- French Guiana
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Suicidal Ideation, Major Depressive Disorder
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse …
- Conditions
- Suicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- LAP-ST vs ECT (NCT06529029)
- Testing
- Sigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Suicide, Attempted
Randomized Controlled and Prospective Trial of a Cohort of People Who Made a Suicide Attempt
The prevention of recurrent suicidal about people who have made a suicide attempt is a major strand in the prevention of suicide. It is estimated that 10-15 % of people who made a suicide attempt die by suicide.
- Trial name
- OSTA (NCT01176929)
- Testing
- Usual treatment and Prevention program, Usual Treatment
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Suicide
Tool for Sibling and Children of Someone With Suicidal Thoughts
This study aims to investigate to what extent a website developed for siblings and children (16-25 years old) of someone with suicidal thoughts and/or behaviors is effective in improving perceived pressure, knowledge, attitudes…
- Trial name
- NCT06100575
- Testing
- Website (www.mee-leven.be)
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent