Clinical trials: Sun Damaged Skin
Photoaging, Weight Loss
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Adult subjects with a history of or currently taking glucagon-like peptide-1 (GLP-1) receptor agonist medication and moderate-to-severe cheek wrinkles and midface contour deficiencies will be treated with Sculptra correction of…
- Conditions
- Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin
- Trial name
- NCT06351358
- Testing
- Sculptra treatment, Restylane Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Aging, Skin Laxity
Association of Leucocyte Telomere Length With DPAS Score in Skin Aging
The goal is to know the profile of photoaging based on clinical examination, Dermoscopic Photoaging Scale and leucocyte telomere length The main questions of Research are: what is the profile of photoaging based on clinical…
- Trial name
- NCT06501547
- Testing
- Leucocyte Telomere Length from blood draw
- Where
- 3 sites in Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Photoaging
Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity
This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.
- Trial name
- NCT05882084
- Testing
- Astaxanthin 6 mg daily
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Photoaging
Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational
The purpose of this study is to determine the improvement in signs of photoaging and subject satisfaction after combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium…
- Trial name
- NCT05039723
- Testing
- Radiesse, Xeomin, Belotero
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Photoaging, Wrinkle
A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum
This double-blind, randomized, placebo-controlled, single-center clinical trial was conducted to assess the efficacy and tolerance of an anti-aging daily serum to improve moderate overall photodamage and skin fatigue after…
- Trial name
- NCT05514782
- Testing
- Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 40+
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging, Photoaging of Skin
Light Emitting Diode (LED) for the Treatment of Wrinkles
The purpose of this study was to determine whether light emitting diode (LED) therapy can improve skin appearance of human subjects with aged/photoaged skin.
- Trial name
- NCT00818246
- Testing
- LumiPhase-R™, OPUSMED Inc. Montreal, Canada
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RoseLab Skin Optics Laboratory
Photoaging
Efficacy of Topical Antioxidants in Tretment of Photoaging
This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.
- Trial name
- NCT04835259
- Testing
- Selenium Amino Acid Chelate (Selenium ACE cream)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging
Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women
Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins.
- Trial name
- NCT04869852
- Testing
- Food
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation
Sun Damaged Skin
Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light
The objective of this study is quantification of singlet oxygen species in the skin after exposure to Ultraviolet A (UVA) light
- Trial name
- NCT05865431
- Testing
- Zinc Oxide and Avobenzone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Photoaging
Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging
Photoaging is a common concern within the cosmeceutical industry with many products that are available. One frequently used product is hydroquinone that is used to even skin tone. However, hydroquinone has several shortcomings.
- Trial name
- NCT04345094
- Testing
- Hexylresourcinol, Hydroquinone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sytheon Ltd.
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photo-aging, Keratosis
The Effect of Efudex Treatment on Photoaged Skin
The researchers propose that skin improvements may be seen following a course of Efudex, (5-fluorouracil), a FDA-approved topical therapy (applied directly to the skin).
- Trial name
- NCT00121511
- Testing
- Efudex (5-fluorouracil)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aging Skin, Body Mass Index
Clinical Profile of Skin Aging Based on Dermoscopy Photoaging Scale and Glogau Scale - Study of Leucocyte Telomere Length, Biomarker P16, and Body Mass Index
To determine the relationship between clinical appearance, dermoscopic examination results of photoaging profiles based on clinical examination, DPAS score and leucocyte telomere length, to analyze the relationship between BMI…
- Conditions
- Aging Skin, Body Mass Index, Cellular Senescence, Triglycerides
- Trial name
- LTLP16 (NCT06779032)
- Testing
- blood draw
- Where
- Indonesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Photoaging, Actinic Keratosis
5fluorouracil for Advanced Photoaging
It is well known the efficacy of 5% 5-fluoruracil for multiple and superficial actinic keratosis (AKs)treatment. Recently its additional benefit for advanced and severe photoaging while treating Aks was reported.
- Trial name
- NCT01405144
- Testing
- 5-fluoruracil
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Skin Health
To Determine the Activity and Mechanisms of Cranberries to Attenuate Skin Photoaging and Improve Skin Health in Women
Previous studies have shown that cranberry phytochemicals scavenge reactive carbonyls. Cranberry polyphenols have been reported to attenuate collagen degradation and inhibit oxidative stress in human cells.
- Trial name
- NCT04183920
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Photoaging
Photoaging Treatment With Imiquimod
Recently it was demonstrated that imiquimod in addition to exerting a repairing effect in pre malignant and malignant lesions caused by UV radiation it reverses histopathological changes associated with the photoaging skin.
- Trial name
- NCT01935310
- Testing
- Imiquimod
- Where
- Colombia
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CES University
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin