Clinical trials: Supportive Therapy
Hypertension
The Impact of Mobile Application-Supported Monitoring on Treatment Compliance and Success in Lifestyle Changes in Hypertensive Patients
Hypertension (HT) is defined as an arterial blood pressure persistently exceeding 140/90 mmHg in repeated measurements. It is a systemic disease characterized by chronically elevated blood pressure, which can lead to severe…
- Trial name
- NCT07299266
- Testing
- Mobile App-Supported Blood Pressure Monitoring
- Volunteers
- 40 people
- Sponsor
- University of Gaziantep
HIV Infections
Viral Kinetics of Treatment With Peginterferon Alpha-2a, Ribavirin and Epoetin β in Patients Coinfected HCV/HIV
The purpose of this study is to compare the early virological response (EVR = undetectable [ribonucleic acid-hepatitis C virus] RNA-HCV or a reduction of > 2 log10) of patients with chronic hepatitis C coinfected with HIV treated…
- Trial name
- NCT00356486
- Testing
- Peginterferon alfa-2a, Ribavirin, epoetin-β, Peginterferon alfa-2a + Ribavirin for 12 weeks
- Where
- 12 sites in Spain
- Volunteers
- 74 people
- Sponsor
- Germans Trias i Pujol Hospital
Metastatic Colorectal Cancer
Xeloda Maintenance Versus BSC in Metastatic Colorectal Cancer
Colorectal cancer (CRC) accounts for 10% to 15% of all cancers and is the second leading cause of cancer deaths in Western countries.
- Trial name
- NCT02060669
- Testing
- Xeloda
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Samsung Medical Center
Chronic Heart Failure, Chronic Kidney Diseases
ODYSSEE-vCHAT Mental Health Program for Heart Failure and Kidney Disease Patients
INTRODUCTION Psychological distress and reduced quality of life are prevalent in patients with chronic heart failure (CHF) and advanced chronic kidney disease (CKD).
- Trial name
- ODYSSEEvCHAT (NCT05560737)
- Testing
- ODYSSEE-vCHAT
- Where
- 4 sites in Canada
- Volunteers
- 215 people
- Sponsor
- University Health Network, Toronto
Occlusal Analysis, Patient Satisfaction
3D Integration of Facial , Intraoral Scanning and CBCT on Patient Satisfaction and Occlusion of Temporary, Permanent Implant Supported Prosthesis
This study will aim to evaluate the effect of complete digital workflow for construction of temporary and permanent full arch implant supported screw retained restoration by the 3D integration of facial scanning, intraoral…
- Trial name
- NCT06846372
- Testing
- occluscence, patient satisfaction
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Inflammatory Arthritis, Palliative Care
Palliative and Supportive Care to Help People With Arthritis to Live Well (ENRICH)
Palliative Care (PC) focuses on maximising quality of life and care for patients and their families in the last 1000 days of life. Supportive Care (SC) is provided earlier in life for people with a long-term health condition.
- Trial name
- ENRICH (NCT07491939)
- Testing
- NONE - observational study
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Dorothy House Hospice
Cancer (Active Cancer, Meaning Not Being Cancer Free), of Any Stage and Involving Any Treatment/Care Regimen; i.e. Curative, Life-extending, or Palliative
International Study to Evaluate a Navigation Program for Older People With Cancer and Their Family Caregivers (EU NAVIGATE Study)
Most people with cancer are older, and this affects millions of Europeans yearly. Integrating high-quality, equitable, and cost-effective care across the continuum of supportive, palliative, and end-of-life care for both patients…
- Trial name
- EU NAVIGATE (NCT06110312)
- Testing
- NavCare-EU
- Volunteers
- 489 people
- Sponsor
- Vrije Universiteit Brussel
Cardiogenic Shock, Acute Decompensated Heart Failure
SURPASS Impella 5.5 Study
A multi-center, prospective \& retrospective, observational single-arm study of the clinical outcomes up to one year collected from electronic health records of patients which have undergone standard of care implantation of…
- Trial name
- NCT05100836
- Testing
- Impella 5.5
- Where
- 15 sites in United States
- Volunteers
- 1,017 people
- Sponsor
- Abiomed Inc.
Tobacco Use Disorder
Computer-Assisted Stop-Smoking Program in Helping Doctors Counsel Patients Who Smoke Cigarettes
RATIONALE: A computer-assisted stop-smoking program may help doctors counsel patients who smoke and may help increase the number of patients who stop smoking.
- Trial name
- NCT00865553
- Testing
- computer-assisted smoking cessation intervention, cancer prevention, educational intervention
- Where
- United States
- Volunteers
- 630 people
- Sponsor
- University of Vermont
Hemorrhage, Bleeding
Validation of a Quantra Supported Hemotherapy Algorithm in Cardiac Surgery
The aim of this study is to develop a coagulation algorithm based on Quantra POCT for the treatment of coagulopathic cardiac surgery patients.
- Trial name
- NCT03902275
- Testing
- Quantra-Algorithm, ROTEM-Algorithm
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Coping Behavior, Emotional Distress
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
The Creative Arts Diabetes Initiative will offer facilitated art therapy with a group/peer-support environment to two groups of youth/young adults, one with type 1 diabetes, and one with type 2 diabetes.
- Conditions
- Coping Behavior, Emotional Distress, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- CADI (NCT02790892)
- Testing
- Art therapy - pre and post test measures
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Advanced Lung Cancer
Exercise, Nutrition, and Palliative Care in Advanced Lung Cancer (ENPAL)
Background: Evidence supports exercise and nutrition as beneficial for enhancing QOL in earlier stages of lung cancer; however, there is minimal research of either intervention - and none with combined interventions - in advanced…
- Trial name
- ENPAL (NCT04575831)
- Testing
- Exercise, Nutrition, and Palliative Symptom Management
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Delirium, Fall Injury
Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study
Through NINR project 1R44NR017842-01 which preceded the present study, the investigators enhanced the care.coach avatar platform to incorporate a robust suite of evidence-based protocols based on the Hospital Elder Life Program…
- Trial name
- AvatarHELP (NCT03832192)
- Testing
- care.coach Avatar (HELP-Protocolized)
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Victor Wang
Radiation Therapy, Chemoradiotherapy
Application of Intelligent Care Systems in Radiation Therapy: Enhancing Patient Safety and Reducing Anxiety Through System Optimization and Real-Time Blood Data Monitoring
This study aims to evaluate the impact of an intelligent care system on radiation therapy patients, focusing on real-time blood data monitoring, optimized patient education, and internal alert systems.
- Conditions
- Radiation Therapy, Chemoradiotherapy, Anxiety, Adherence
- Trial name
- ICS-RT (NCT06833801)
- Testing
- Real-Time Blood Data Monitoring System (Device/Software Integration), Enhanced Patient Education Materials (Behavioral/Educational Intervention), Internal Warning Signs and Alerts (Behavioral Intervention)
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chung Shan Medical University
Opioid Use Disorder, mHealth
Personalized Addiction Treatment enHancement
Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death.
- Conditions
- Opioid Use Disorder, mHealth, Peer Support
- Trial name
- Project Path (NCT07778394)
- Testing
- Vira Platform, Treatment-As-Usual
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rhode Island Hospital
Invasive Mechanical Ventilation
Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support
Invasive mechanical ventilation is one of the most important and life-saving therapies in the intensive care unit (ICU). In most severe cases, extracorporeal lung support is initiated when mechanical ventilation is insufficient.
- Trial name
- IntelliLung (NCT05668637)
- Testing
- Artificial Intelligence-based Decision support
- Where
- 8 sites in United States, Germany and 3 more
- Volunteers
- 318,542 people
- Sponsor
- Technische Universität Dresden
Locally Advanced Esophageal Cancer, Gastroesophageal Junction Cancer
Comprehensive Perioperative Program Based on Prehabilitation, Nutritional Intervention and Psychological Support for Patients With Locally Advanced Operable Oesophagogastric Cancer
Perioperative chemotherapy (CHT) or CHT/RT combined with surgery is the standard therapeutic approach for the treatment of locally advanced cancer of the esophagus, gastroesophageal junction (GEJ), and stomach.
- Conditions
- Locally Advanced Esophageal Cancer, Gastroesophageal Junction Cancer, Gastric Cancer
- Trial name
- OESOFIT (NCT07671625)
- Testing
- Cardiorespiratory fitness (FsPS), Exercises you can do on your own at home, Enhanced Recovery After Surgery ERAS
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Masaryk Memorial Cancer Institute
Congenital Heart Disease
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will…
- Trial name
- IMMPACT (NCT03891160)
- Testing
- 3D model of heart
- Where
- 6 sites in United States
- Volunteers
- 36 people
- Sponsor
- Columbia University
Childhood Obesity, Disordered Eating
Disordered Eating Risk in Pediatric Obesity Treatment Using a Digi-Physical Tool
The goal of this observational study is to evaluate the risk of developing disordered eating behavior or an eating disorder among children and adolescents with obesity who have used a digi-physical treatment tool with daily…
- Conditions
- Childhood Obesity, Disordered Eating, Binge Eating Disorder, Anorexia Nervosa
- Trial name
- NCT06807489
- Testing
- Digi-physical treatment tool
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- Karolinska Institutet
Mental Disorders
Enhanced Medication Reconciliation For Serious Mental Illness
The purpose of this study is to evaluate the clinical utility of a decision support tool, the Patient Medication Profile(TM), developed by Sano Informed Prescribing on medication reconciliation and identification of drug-related…
- Trial name
- NCT03169868
- Testing
- Sano Patient Medication Profile
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Precera Bioscience, Inc.
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