Clinical trials: Supportive Therapy
Acute Leukaemia in Relapse
Early Palliative Care in Patient With Acute Leukaemia
Several studies have shown that patients with acute leukemia have many symptoms during disease These symptoms decrease the quality of life and may even appear or worsen other symptoms such as depression Several studies point to…
- Trial name
- Pablo Hemato (NCT02631811)
- Testing
- Supportive /palliative care intervention
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Hospices Civils de Lyon
Osteoarthritis, Knee, Osteoarthritis, Hip
Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity
Chronic conditions such as knee or hip osteoarthritis (OA), chronic obstructive pulmonary disease (COPD), heart failure (HF), coronary heart disease (CHD), hypertension, type 2 diabetes mellitus (T2DM) and depression are among…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Heart Failure, Coronary Heart Disease
- Trial name
- MOBILIZE (NCT04645732)
- Testing
- Personalized exercise therapy and self-management support program, Usual care
- Where
- 16 sites in Denmark
- Volunteers
- 228 people
- Sponsor
- University of Southern Denmark
Suicide Prevention
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk
The investigators are modifying and testing the preliminary effectiveness and implementation of the combination of two psychosocial interventions, Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and the…
- Trial name
- NCT06941311
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Treatment Adherence and Compliance
Quality and Effectiveness of a Personalised App to Support Patients With Fixed Braces
Mobile phones are potentially an invaluable tool in improving adherence, they are readily available and can utilised to deliver several approaches to improve adherence simultaneously.
- Trial name
- NCT04184739
- Testing
- My Braces App
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University College, London
Aplastic Anemias
Umbilical Cord Blood-Supported Haplo-HSCT for Aplastic Anemia Treatment Study
Aplastic anemia (AA) is a rare bone marrow failure syndrome with an annual incidence of about 0.74/100,000, affecting all ages but more common in the elderly.
- Trial name
- NCT06650553
- Testing
- Clinically diagnosed AA patients are divided into HLA-matched HSCT group and umbilical cord blood-supported haplo-HSCT group.
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanxi Bethune Hospital
Metastatic Colorectal Cancer, Advanced Colorectal Cancer
Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer
RBS2418 is a specific immune modulator that works through the inhibition of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) and is designed to lead to anti-tumor immunity by protecting endogenous 2'-3'-cyclic guanosine…
- Trial name
- VISTA-1 (NCT06824064)
- Testing
- RBS2418
- Where
- 5 sites in United States, Puerto Rico and 1 more
- Volunteers
- 150 people
- Sponsor
- Riboscience, LLC.
HIV
Evaluation of Use of Clinical Decision Support System in HIV Care in Resource Constrained Settings
The purpose of this study is to determine whether the use of a Computerized Decision Support System (CDSS) in form of alerts to clinicians enhances early detection of immunological treatment failure in HIV patients.
- Trial name
- CDSS (NCT01634802)
- Testing
- EMR Only, EMR+CDSS
- Where
- Kenya
- Volunteers
- 1,460 people
- Sponsor
- Kenya Medical Research Institute
Alcohol Use Disorder, Alcohol Associated Liver Disease
A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease
This study seeks to develop and test a novel digital pill system (DPS) that measures real-time medication ingestion and pairs it with a cognitive behavioral therapy (CBT)-based intervention to provide personalized, data-driven…
- Conditions
- Alcohol Use Disorder, Alcohol Associated Liver Disease, Medications for Alcohol Use Disorder, Behavioral Medicine
- Trial name
- NCT07553377
- Testing
- AcamproSync
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Gastrointestinal Cancer
EAT-ING: Enhancing Anticancer Treatment Safety Via Immunomodulatory Nutritional Support in Advanced Gastrointestinal Cancers
The use of immunomodulants in patients with GI cancer has been progressively gaining attention in the last years, as a high-calorie-high-protein nutritional blend enriched in immunonutrients has shown efficacy in several studies…
- Trial name
- EAT-ING (NCT07590622)
- Testing
- LH BLU, ONS
- Volunteers
- 88 people
- Sponsor
- IRCCS San Raffaele
Cancer
A Study Comparing Pegylated Filgrastim and Filgrastim in Support for Chemotherapy
Neutropenia is one of the most frequent adverse effects of chemotherapy, and the main factor to limit the dosage and delay the schedule of chemotherapy.
- Trial name
- NCT01285219
- Testing
- pegylated filgrastim and filgrastim, filgrastim and pegylated filgrastim
- Volunteers
- 337 people
- Sponsor
- Chinese Academy of Medical Sciences
Triple Negative Breast Cancer (TNBC)
A Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer
The purpose of this study is to explore the feasibility and acceptability of a nurse-led, coping, and supportive care intervention for patients with triple-negative breast cancer.
- Trial name
- RESTORE (NCT07513311)
- Testing
- RESTORE, Enhanced Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Atrial Fibrillation
Integrated Management Program Advancing Community Treatment of Atrial Fibrillation
Research Question: Among community-based patients with AF, does providing an integrated Clinical Decision Support System (CDSS) to providers and patients improve process of care and clinical outcomes, and decrease the healthcare…
- Trial name
- IMPACT-AF (NCT01927367)
- Testing
- Clinical Decision Support System for AF
- Where
- 2 sites in Canada
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- Jafna L Cox
Opioid Use, Pain
Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in Patients With Chronic Non-Cancer Pain
This study will use a randomized controlled design to test whether medical marijuana use by adults on high-dose chronic opioid therapy (COT) for chronic non-cancer pain is associated with reduced opioid dose and improved pain…
- Conditions
- Opioid Use, Pain, Marijuana Use
- Trial name
- NCT04827992
- Testing
- Cannabis, Prescription Opioid Taper Support (POTS)
- Where
- 3 sites in United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1
Evaluation of Exercise Testing and Physical Activity in Children and Adolescents Living With Inherited Arrhythmias
The goal of this observational study is to evaluate exercise testing and daily physical activity in children and adolescents who are diagnosed with an inherited arrhythmia.
- Conditions
- Long QT Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia Type 1, Catecholaminergic Polymorphic Ventricular Tachycardia Type 2
- Trial name
- ACTIVELY (NCT06661278)
- Testing
- Exercise tolerance test, Physical activity & heart rate monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Obesity, Weight Loss
Efficacy of Diet and Hypnotic Suggestions or Telemedicine in Obesity Management
The aim of the study is the assessment of the effectiveness of medical nutrition therapy (MNT) among obese patients, including a well-balanced low-calories diet, an individual dietary counseling conducted by dietitians and…
- Trial name
- TASTY (NCT03811197)
- Testing
- Dietary counseling via face to face meeting, Telemedicine, Hypnotic Suggestions
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Warsaw University of Life Sciences
Non-Small-Cell Lung Carcinoma
ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures
This study is being carried out to assess if adding ZD6474 to best supportive care (BSC) is more effective than best supportive care alone, for the treatment of patients with non-small cell lung cancer, whose disease has recurred…
- Trial name
- NCT00404924
- Testing
- ZD6474 (vandetanib), Best Supportive Care
- Where
- 102 sites in United States, Argentina and 20 more
- Volunteers
- 1,140 people
- Sponsor
- Genzyme, a Sanofi Company
Fibromyalgia, Chronic Fatigue Syndrome
Treatment of Fibromyalgia With Recovery Factors
Treatment of Fibromyalgia and CFS with Recovery Factors
- Trial name
- NCT04381780
- Testing
- Recovery Factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Practitioners Alliance Network
Mental Illness, Tobacco Smoking
Decision Support for Smoking Cessation in Young Adults With Severe Mental Illness
Up to 77% of young people with severe mental illnesses smoke, a rate that is up to five times higher than the rate of daily smoking in other young adults.
- Conditions
- Mental Illness, Tobacco Smoking, Psychotic Disorders
- Trial name
- NCT01779440
- Testing
- Electronic Decision Support System
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Parkinson Disease
DESENSITIZE-PD: Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Support Dopaminergic Desensitization in PD
20 patients with idiopathic Parkinson's disease, who are planned to undergo intestinal L-Dopa + entacapone (Lecigon®) treatment will be included into this observational single-armed study.
- Trial name
- NCT05579379
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Patient Satisfaction, Cancer
Patient Satisfaction Following Multidisciplinary Cancer Care Assessment in Day Hospital.
This study aims to evaluate patient satisfaction following a multidisciplinary "complex assessment" conducted in a Day Hospital setting at the Centre Hospitalier de Martigues.
- Conditions
- Patient Satisfaction, Cancer, Quality of Health Care
- Trial name
- EVAQSAP-HDJ-BC (NCT07560423)
- Testing
- Multidisciplinary Complex Assessment
- Where
- France
- Volunteers
- 309 people
- Sponsor
- Centre Hospitalier de Martigues
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