Clinical trials: Surgery, Plastic, open to volunteers
Mucogingival Defects, Pontic Site Development
Pontic Site Development With or Without Fixed Partial Denture
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects.
- Conditions
- Mucogingival Defects, Pontic Site Development, Keratinized Tissue Deficiency, Connective Tissue Graft
- Trial name
- Pontic Site (NCT07535060)
- Testing
- Connective Tissue Graft (CTG)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer
Effect of Breast Implants om Mammography Screening
The purpose of the study is to survey how many women have breast implants in the mammography screening population and the effect of implants on the number and type of examinations and on costs.
- Trial name
- NCT05222100
- Testing
- Mammography screening
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Vastra Gotaland Region
Surgical Complication
The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery
Study objective: This is a study to investigate whether applying the drug tranexamic acid (TXA) onto a surgical wound surface may affect the incidence of surgical complications such as re-bleeding needing intervention, wound…
- Trial name
- TRANOP (NCT06270407)
- Testing
- Tranexamic Acid 100 MG/ML, 0.9%sodium chloride
- Where
- 11 sites in Denmark, Finland and 1 more
- Volunteers
- 3,000 people
- Sponsor
- St. Olavs Hospital
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Breast Cancer
Effects of Expectations and Body Image in Breast Reconstruction
A breast reconstruction after mastectomy, either due to breast cancer or a high lifetime risk for cancer, is performed to increase the patient's quality of life.
- Trial name
- NCT04714463
- Testing
- Implant-based breast reconstruction, Autologous breast reconstruction, Combined methods
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer, Breast Hypertrophy
Validation of Scales in Reconstructive Breast Surgery
The main purpose of the project is to validate patient reported outcomes measures (PROMs) in reconstructive breast surgery. BREAST-Q will be evaluated for Swedish and Sweden.Hospital Anxiety and Depression Scale (HADS), EuroQol…
- Trial name
- ValPlast (NCT05233891)
- Testing
- Breast reconstruction, Breast reduction
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Vastra Gotaland Region
Pelvic Organ Prolapse
Long-term Success Rate of Transvaginal Mesh for the Treatment of Pelvic Organ Prolapse: The Extended RCT Study
The original RCT trial is designed to compare self-tailored titanium-coated polypropylene mesh procedure with mesh-kit in the treatment of POP stage III-IV in terms of efficacy, safety and cost-effective at 1-year follow-up.
- Trial name
- NCT05938881
- Testing
- self-cut mesh procedure, mesh-kit procedure
- Where
- 11 sites in China
- Volunteers
- 336 people
- Sponsor
- Peking Union Medical College Hospital
Gingival Recession, Localized, Gingival Recession, Plastic Surgery
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.
Multiple techniques can be used for recession coverage. The most common techniques are : tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF).
- Conditions
- Gingival Recession, Localized, Gingival Recession, Plastic Surgery, Gingival Recessions, Gingival Recession, Mucogingival Surgery
- Trial name
- NCT06940050
- Testing
- Coronally advanced flap with a connective tissue graft, Tunneled coronally advanced flap with a connective tissue graft
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- University Hospital, Ghent
Plastic Surgery Procedures
Safety and Feasibility of the MACS in Surgical Procedures: A Prospective Multi-Center Study
The goal of this clinical trial is to evaluate the safety and performance of the MACS device in adults undergoing elective plastic surgery procedures.
- Trial name
- NCT07470411
- Testing
- MACS System
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Levita Magnetics
Surgery
Virtual Assistant for Plastic Surgery Patients
Researchers are trying determine the long term impact when patients have access to the artificial intelligence virtual assistant (AIVA) as a complimentary resource.
- Trial name
- NCT04017351
- Testing
- Artificial Intelligence Virtual Assistant
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Microtia, Congenital, Microtia
Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction
This study aims to improve surgical outcomes for children and young adults with ear differences severe secondary to congenital conditions (like microtia, a condition where the ear is underdeveloped), trauma (such as dog bites)…
- Conditions
- Microtia, Congenital, Microtia, Microtia-Anotia, Ear Deformities, Acquired
- Trial name
- NCT07154667
- Testing
- Use of AuryzoN™ EAR 2.0 device, Hand carving
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nemours Children's Clinic
Breast Reconstruction, Breast Cancer
Optimizing Postoperative Recovery After Breast Reconstruction With Autologous Tissue (BestDIEP)
Women who have their breast reconstructed with autologous tissue seem to be more satisfied with their breast. However, autologous breast reconstruction entails a bigger operation, and the usage of more health care resources, than…
- Trial name
- BestDIEP (NCT05363189)
- Testing
- Venous augmentation, Traditional ERAS (enhanced recovery after surgery) protocol, Sahlgrenska recovery protocol
- Where
- Sweden
- Volunteers
- 380 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer, Breast Reconstruction
Implant-based Breast Reconstruction in Post-bariatric Women - a Registry-based National Study
The goal of this national registry-based study is to investigate the prevalence of reconstructive breast surgery and risk factors for surgical complications in women who have had weight loss surgery previously.
- Conditions
- Breast Cancer, Breast Reconstruction, Bariatric Surgery, Breast Implant
- Trial name
- NCT07059104
- Testing
- Breast augmentation, Breast reconstruction after mastectomy
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Vastra Gotaland Region
Postoperative Delirium, Postoperative Cognitive Dysfunction
Bilateral Bispectral Index, Asymmetries and Post-operative Delirium
The primary objective of the study is to describe the value of interhemispheric asymmetry (ASYM), during the different intra- and peri-operative phases, in those patients who develop or do not develop post-operative delirium…
- Trial name
- DELBIS (NCT06761573)
- Testing
- Bilateral Bispetral Index Monitor will be applied on forehead of our patients, before surgery begins
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Anterior Cruciate Ligament Rupture With Ligamentoplasty
Evaluation of the Evolution of Proprioceptive Reweighting Abilities Following Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) injury is the most common knee injury among athletes who play contact sports involving pivoting.
- Trial name
- ReproEVO (NCT07389850)
- Testing
- ReproEVO intervention
- Where
- 3 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
Altered Passive Eruption
Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption
This prospective, single-group interventional study will evaluate the stability of periodontal tissues after esthetic periodontal surgery for the correction of altered passive eruption in individuals with excessive gingival…
- Trial name
- NCT07762482
- Testing
- Esthetic Crown-Lengthening Surgery
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Free Mucogingival Grafts, Gingival Recession
Free Mucogingival Graft for Isolated Root Coverage
The goal of this clinical trial is to to describe and evaluate an approach, free mucogingival graft (FMG), in periodontal plastic surgery for root coverage (RC) in lower incisor gingival recessions (GR) with mucogingival…
- Conditions
- Free Mucogingival Grafts, Gingival Recession, Root Coverage, Periodontal Plastic Surgery
- Trial name
- NCT05851248
- Testing
- Buccal muco-gingival tissue graft, Palatal connective tissue graft
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad de Murcia
Head and Neck Surgery, Plastic Surgery
Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty
Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements.
- Conditions
- Head and Neck Surgery, Plastic Surgery, Rhinoplasty, Pain
- Trial name
- PRISM (NCT07233538)
- Testing
- Maxillary block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Surgical Drain
Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications
The objective of this study is to evaluate whether surgical drain securement with a novel sutureless device (K-LOCKTM) will improve patient quality of life and reduce postoperative drain-related complications compared to drain…
- Trial name
- NCT06916286
- Testing
- K-Lock, Suture
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Wake Forest University Health Sciences
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine