Clinical trials: Surgery With General Anesthesia
Oropharyngeal Leak Pressure
The Effects of GMA-TULIP, I-gel, and BlockBuster Laryngeal Mask in Surgeries With Lateral Position Under General Anesthesia
To compare the efficacy and safety of traditional inflatable laryngeal mask, i-gel non-inflatable laryngeal mask and GMA-TULIP non-inflatable laryngeal mask in surgeries with lateral position under general anesthesia, so that…
- Trial name
- NCT06782841
- Testing
- GMA-TULIP Laryngeal Mask, i-gel Laryngeal Mask, BlockBuster Laryngeal Mask
- Where
- China
- Volunteers
- 102 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Surgery With General Anesthesia, Depression - Major Depressive Disorder
Perioperative Depression, an Observational Cohort Study
This observational cohort study studies two aspects of perioperative depression. First, it examines the postoperative morbidity and mortality among patients with preoperative depression.
- Trial name
- NCT06783842
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Karolinska Institutet
Rotator Cuff Tears, Rotator Cuff Injuries
Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries
This study is comparing total intravenous anesthesia with propofol with a regional nerve block against general anesthesia with a regional nerve block on the primary endpoint of time to meet discharge criteria.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury
- Trial name
- TIVA (NCT04793022)
- Testing
- TIVA with Propofol, Inhaled Anesthesia
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Transcervical Resection of Endometrium, Transcervical Resection of Fibroids
Comparing Two Types of Sedation to Gynaecological Patients
The primary endpoint is to investigate the difference in pain between patients who receive deep sedation with spontaneous breathing versus patients who receive general anesthesia.
- Conditions
- Transcervical Resection of Endometrium, Transcervical Resection of Fibroids, Transcervical Resection of Polyp
- Trial name
- NCT01412632
- Testing
- Remifentanil, propofol and citanest
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neuromuscular Blockade, Postoperative Complications
Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery
The investigators will conduct a prospective, randomized trial to assess the impact of neuromuscular blockade on early (<72 hours post-ICU admission) postoperative respiratory complications in cardiac surgical patients.
- Trial name
- NCT02635542
- Testing
- Succinylcholine, Cisatracurium
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Behavior Problem
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children
The goal of this clinical trial is to learn whether intranasal dexmedetomidine or esketamine given before anesthesia can reduce negative postoperative behavioral changes in children undergoing day surgery.
- Trial name
- PEDI-NPOBCs (NCT07570160)
- Testing
- Dexmedetomidine, Esketamine, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Nanjing Children's Hospital
Anesthesia, Fluid Responsiveness
Assessment Of Carotid Flow During General Anesthesia
Proper identification of patients who would benefit from fluid infusion (fluid responsiveness) is one of the most crucial challenges in anaesthesia and critical care.
- Trial name
- NCT03713008
- Testing
- Fluid bolus
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Medical University of Warsaw
Postoperative Pain, Upper Extremity Fracture
Ropivacaine Alone Versus Ropivacaine Plus Lidocaine With or Without Epinephrine for Supraclavicular Brachial Plexus Block in Upper Limb Orthopedic Surgery
This randomized controlled trial compared three local anesthetic solutions for ultrasound-guided supraclavicular brachial plexus block in adults aged 18 to 59 years undergoing upper limb orthopedic and trauma surgery at a general…
- Conditions
- Postoperative Pain, Upper Extremity Fracture, Anesthesia, Conduction
- Trial name
- NCT07907666
- Testing
- ropivacaine, lidocaine, lidocaine with epinephrine
- Where
- Mexico
- Volunteers
- 138 people
- Sponsor
- Instituto Mexicano del Seguro Social
Ankle Fracture in Need of Surgical Fixation
The Effect of Nerve Blockades in Addition to General Anesthesia in Surgical Fixation of Ankle Fractures.
This clinical, randomized, and controlled study will provide valuable scientific evidence regarding the effect of adding peripheral nerve blockades to general anaesthesia during ankle surgery.
- Trial name
- NCT01923623
- Testing
- Ropivacaine block
- Sponsor
- Herlev Hospital
General Anesthesia, Airway Management
I-gel Plus Supraglottic Airway Device for Surgical Procedures in Prone Position
I-gel Plus is a novel supraglottic airway device that has been evaluated in various studies with high success and low complication rates.
- Conditions
- General Anesthesia, Airway Management, Supraglottic Airway
- Trial name
- NCT06602817
- Testing
- Exposure: prone position, Exposure: Supine position
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
Pain, Postoperative
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
The purpose of this study is to investigate the effectiveness of various oral analgesic regimens in minimizing post-operative pain and discomfort in young children following dental rehabilitation under general anesthesia (DRGA).
- Trial name
- NCT06757075
- Testing
- Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
A Study on the Effect of Animation-based Nurse-Patient Interaction Model on Postoperative Pain in Children With Congenital Heart Disease
Application of Nurse-Patient Interaction Model Based on Animated Cartoons in Postoperative Analgesia for Preschool Children With Congenital Heart Disease.
I. Research Objective To verify the efficacy of an animated nurse-patient interaction model in alleviating postoperative pain in children with congenital heart disease, optimize non-pharmacological analgesic nursing processes for…
- Trial name
- CCU (NCT07319260)
- Testing
- Routine care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Beijing Children's Hospital
Fever, Scoliosis
Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis
Fever is a common clinical symptom in patients with postoperative scoliosis. However, there are rare reports of immediately fevers occurring following operative procedures.
- Conditions
- Fever, Scoliosis, Surgical Trauma, Hypothermia
- Trial name
- NCT06405659
- Testing
- correction for pedicle fixation
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Obesity, Obstructive Sleep Apnea
Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35
This study proposes to evaluate the clinical applicability of the ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA) in obese surgical patients undergoing general anesthesia.
- Trial name
- NCT01825278
- Testing
- ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Tufts Medical Center
Surgical Procedure, Unspecified
Thoracic Epidural Versus General Anaesthesia in Cholecystectomy
CONTEXT AND AIMS: The aim of the study is to compare patients satisfaction of thoracic epidural and general anesthesia procedures in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- EVGAC (NCT03107832)
- Testing
- thoracic epidural anesthesia procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Abant Izzet Baysal University
General Surgery
Sugammadex vs Placebo to Prevent Residual Neuromuscular Block
The study is designed to determine whether patients who receive sugammadex immediately after tracheal extubation will exhibit a decrease in the incidence of postoperative residual paralysis and an associated decrease in the…
- Trial name
- NCT02728726
- Testing
- Sugammadex
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Mayo Clinic
Anesthesia, Regional
Comparison of an Interscalene Nerve Block With or Without Stellate Ganglion Block for Shoulder Surgery
This study describes the difference of analgesic effect of levobupivacaine 0.5% administered through an interscalene nerve block with or without a stellate ganglion block.
- Trial name
- NCT02879916
- Testing
- Levobupivacaine, NaCl 0.9%
- Volunteers
- 30 people
- Sponsor
- University Hospital, Antwerp
Laryngoscopic Stress Response, Video Laryngoscopy
Effect of Video Laryngoscopy Versus Conventional Laryngoscopy Upon Hemodynamics
In general anestheisa airway is secured by passing a tube down the widpipe. This helps the patient to breath via ventilator during anesthesia.
- Conditions
- Laryngoscopic Stress Response, Video Laryngoscopy, Conventional Laryngoscopy
- Trial name
- NCT07300878
- Testing
- C MAC hyperangulated video laryngoscopy, Conventional macintosh laryngoscopy
- Where
- Pakistan
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences