Clinical trials: Surgery for Colorectal Cancer.
Mortality, Surgery
Mortality Score in Elderly Patients With Colon Cancer
CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a…
- Conditions
- Mortality, Surgery, Colon Cancer
- Trial name
- MECC (NCT04538404)
- Testing
- Colon Surgery
- Where
- 2 sites in Italy
- Volunteers
- 385 people
- Sponsor
- University of Bologna
Colorectal Cancer, Comprehensive Transitional Care Program
A Pilot Randomized Trial of a Comprehensive Transitional Care Program for Colorectal Cancer Patients
The primary hypothesis is that a comprehensive transitional care program based on the premise of a patient-centered medical home versus routine care reduces emergency room visits and hospital readmissions without increasing costs…
- Trial name
- NCT02202096
- Testing
- Patient education: One-on-one visit, Discharge planning: Assessment of barriers to discharge, Medication reconciliation: Patient medication review
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Rectal Cancer, for Bowel Dysfunction Following Surgery for Rectal Cancers
Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation
The purpose of this study is to evaluate whether a medical device/implant (InterStimTM) will help patients to have more normal bowel movements. The InterStimTM device is a neuromodulating device.
- Trial name
- NCT02163187
- Testing
- Implantation of the InterStimTM, MSK BFI questionnaires, The Low Anterior Resection Score (LARS) questionnaires
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Neoplasm, Colorectal Cancer
Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases
This is a multicentre, open-label, parallel-group, phase II-III, superiority study that randomises patients with isolated resectable colorectal peritoneal metastases in a 1:1 ratio to receive either perioperative systemic therapy…
- Conditions
- Colorectal Neoplasm, Colorectal Cancer, Colorectal Neoplasms Malignant, Colorectal Carcinoma
- Trial name
- CAIRO6 (NCT02758951)
- Testing
- Perioperative systemic therapy, Perioperative CAPOX-bevacizumab, Perioperative FOLFOX-bevacizumab
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 358 people
- Sponsor
- Koen Rovers
Nutrition Related Neoplasm/Cancer, Colorectal Cancer
Postoperative Diet With Hyperproteic Supplement Versus a Supplement With Imunonutrients, in Colorectal Cancer Surgery
The study is a randomized, multicentric, double-blind, controlled with active comparator, parallel groups trial, to demonstrate the non-inferiority in efficacy and therapeutic safety of the postoperative diet with…
- Conditions
- Nutrition Related Neoplasm/Cancer, Colorectal Cancer, Surgery--Complications, Site Infection
- Trial name
- NUTRICOLON (NCT04059731)
- Testing
- Nutrition supplement
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Colonic Neoplasms, Colon Cancer
Systemic and Peritoneal Inflammatory Response In Robotic-assisted And Laparoscopic Surgery for Colon Cancer
The current hypothesis is that robotic-assisted surgery results in a reduced systemic and peritoneal inflammatory response (SIRS) compared to laparoscopic surgery in the treatment of colon cancer.
- Conditions
- Colonic Neoplasms, Colon Cancer, Systemic Inflammatory Response Syndrome, Inflammation
- Trial name
- NCT04687384
- Testing
- Robotic-assisted colectomy, Conventional laparoscopic colectomy
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Southern Denmark
Colorectal Cancer
Natural Orifice Transluminal Endoscopic Surgery for Colorectal Cancer
The purpose of this study is to assess different hybrid natural orifice transluminal endoscopic surgery techniques in management of colorectal cancer as regard: feasibility of the technique, short term oncologic outcome and…
- Trial name
- NOTES (NCT02549456)
- Testing
- natural orifice specimen extraction, Laparoendoscopic resection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Colon Cancer
Personalizing Colorectal Cancer Medicine (ImmuCol2)
Colorectal cancers are the leading cancers for both sexes combined. They represent 15-20% of all cancers. This cancer has a severe prognosis, the survival rate at 5 years is around 55% and in France it is estimated, all…
- Trial name
- ImmuCol2 (NCT02274753)
- Where
- 9 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer, Robotic
The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer
Anastomotic complications are serious complications after anus preserving surgery for rectal cancer,the instrument anastomosis technology are one of the factors that influence the occurrence of anastomotic complications after…
- Conditions
- Rectal Cancer, Robotic, Anastomotic Leak, Laparoscopic
- Trial name
- NCT05667181
- Testing
- Surform
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Nanchang University
Colorectal Cancer
A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer
This 2 arm study will compare the efficacy and safety of intermittent oral Xeloda plus Eloxatin (oxaliplatin) with that of fluorouracil/leucovorin in patients who have had surgery for colon cancer and no previous chemotherapy.
- Trial name
- NCT00069121
- Testing
- Capecitabine, Oxaliplatin, Leucovorin (LV)
- Where
- 232 sites in United States, Australia and 27 more
- Volunteers
- 1,886 people
- Sponsor
- Hoffmann-La Roche
Laparoscopic Colorectal Surgery, Colorectal Cancer
Local Wound Infiltration With 0.5% Levobupivacaine for Postoperative Pain After Laparoscopic Colorectal Surgery.
The study design is a prospective randomized, double-blind, controlled trial of patients who are due to have elective laparoscopic colorectal surgery in Ramathibodhi Hospital.
- Trial name
- NCT03433014
- Testing
- 0.5% Levobupivacaine, Control
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Rectal Cancer
TNFerade™ Plus Chemo/Radiation/Surgery for Rectal Cancer
The purpose of this study is to determine if the addition of TNFerade™ to pre-operative chemoradiotherapy increases the number of pathologic complete responses when compared to pre-operative chemoradiotherapy alone as assessed…
- Trial name
- NCT00137878
- Testing
- TNFerade™
- Where
- United States
- Sponsor
- GenVec
Rectal Adenocarcinoma, Colon Adenocarcinoma
Audit of Surgery for Colorectal Cancer
The aim of this project is to audit the surgical care in patients treated for colorectal adenocarcinoma. This study focused on collecting data from all consecutive cases of colon and rectal adenocarcinoma operated at the National…
- Trial name
- AuditCR (NCT04349384)
- Testing
- Colorectal resection
- Where
- Morocco
- Volunteers
- 136 people
- Sponsor
- Institut National d'Oncologie, Morocco
Rectal Cancer
Side-to-end Anastomosis Versus Colon J Pouch for Reconstruction After Low Anterior Resection for Rectal Cancer (SAVE)
Primary hypothesis: Side-to-end anastomosis is non-inferior to colon J pouch for reconstruction after low anterior resection for rectal cancer in fecal incontinence (Wexner score).
- Trial name
- SAVE (NCT01006577)
- Testing
- side-to-end anastomosis, colon j pouch
- Where
- Germany
- Volunteers
- 306 people
- Sponsor
- Charite University, Berlin, Germany
Colon Cancer
PrehabPal: A Digital Tool to Help Older Adults Prepare for Cancer Surgery
This is a multi-center, randomized trial investigating the use of PrehabPal web app versus a written surgery prehabilitation instructions among individuals aged 65 years and older preparing for colon cancer surgery.
- Trial name
- NCT05520866
- Testing
- PrehabPal
- Where
- 3 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Francisco
Pancreatic Ductal Adenocarcinoma, Colorectal Adenocarcinoma
A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal Adenocarcinoma
The goal of this clinical trial is to learn whether the Ad5.F35-hGCC-PADRE vaccine is safe and can stimulate an immune response against gastrointestinal (GI) cancers in patients with pancreatic, colorectal, esophageal, gastric…
- Conditions
- Pancreatic Ductal Adenocarcinoma, Colorectal Adenocarcinoma, Gastric Adenocarcinoma, Clinical Stage II Gastric Cancer AJCC v8
- Trial name
- NCT04111172
- Testing
- Adenovirus 5/F35-Human Guanylyl Cyclase C-PADRE
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Colorectal Neoplasms, Neoplasms Malignant
Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer
In this study, the investigators will compare the clinical outcomes of the natural orifice specimen extraction surgery versus traditional robotic-assisted surgery in the treatment of colorectal cancer.
- Conditions
- Colorectal Neoplasms, Neoplasms Malignant, Complication of Surgical Procedure, Robotic Surgical Procedures
- Trial name
- NOTR (NCT04230772)
- Testing
- Natural Orifice Specimen Extraction Surgery, Traditional Robotic-assisted Surgery
- Where
- 7 sites in China
- Volunteers
- 550 people
- Sponsor
- Taiyuan Li
Colon Neoplasm
Effect Analysis of Neoadjuvant Chemoradiotherapy Combined With Surgery in Laparoscope for Advanced Colon Cancer
In this study, a randomized controlled trial was conducted on advanced colon cancer patients with preoperative tumor staging T1-4/N1-2/M0 or T4/N0/M0 to determine the effectiveness of preoperative short-term radiotherapy combined…
- Trial name
- NCT05279612
- Testing
- Short-term neoadjuvant chemoradiotherapy
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Tang-Du Hospital
Rectal Tumors, Erectile Dysfunction
Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer
Although the high prevalence of erectile dysfunction (ED) was detected among male patients after the treatment for colorectal cancer, published reports depicting the erectile dysfunction experience of patients with colorectal…
- Trial name
- NCT01912586
- Testing
- vacuum erection device
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Carcinoma (CRC)
Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma
The primary goal of the patient-led follow-up from home, is the improvement of quality of life and the reduction of stress in patients, while obtaining a more complete picture of their health status.
- Trial name
- PROMISE (NCT06613581)
- Testing
- Home-based follow-up
- Where
- 5 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center